PDB: 81877 件ウェブページステータス検索Chemie searchBIRD

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1M6R	Crystal structure of rGd(CGCGCG) forming hexamer Z-DNA duplex with 5'-(rG) overhang 分子名称: 5'-R(*G)D(*CP*GP*CP*GP*CP*G)-3' 著者 Pan, B, Sundaralingam, M. 登録日 2002-07-17 公開日 2003-02-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal structure of rGd(CGCGCG): a Z-DNA hexamer duplex with a 5'-(rG) overhang. Acta Crystallogr.,Sect.D, 59, 2003
2O2C	Crystal structure of phosphoglucose isomerase from T. brucei containing glucose-6-phosphate in the active site 分子名称: GLUCOSE-6-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase, ... 著者 Arsenieva, D, Mazock, G.H, Appavu, B.L, Jeffery, C.J. 登録日 2006-11-29 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal structure of phosphoglucose isomerase from Trypanosoma brucei complexed with glucose-6-phosphate at 1.6 A resolution Proteins, 74, 2008
6J9Q	Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP. 分子名称: GLYCEROL, Glycerol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. 登録日 2019-01-24 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Reaction mechanism of the reverse reaction of African human trypanosomes glycerol kinase. To Be Published
6JAF	Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with PPi (pyrophosphatase reaction) 分子名称: GLYCEROL, Glycerol kinase, PYROPHOSPHATE 2- 著者 Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, Bringaud, F, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. 登録日 2019-01-24 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Glycerol Kinase of African Human Trypanosomes Possesses a Pyrophosphatase Activity. To Be Published
6J9X	Crystal structure of Trypanosoma brucei gambiense glycerol kinase phosphorylated at Thr12(pyrophosphatase reaction) 分子名称: GLYCEROL, Glycerol kinase 著者 Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, Bringaud, F, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. 登録日 2019-01-24 公開日 2020-01-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Glycerol Kinase of African Human Trypanosomes Possesses a Pyrophosphatase Activity. To Be Published
6HE9	PAN-proteasome in state 2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.35 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6HEA	PAN-proteasome in state 3 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.04 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6HEC	PAN-proteasome in state 4 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.95 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6HED	PAN-proteasome in state 5 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.95 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6HE8	PAN-proteasome in state 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Majumder, P, Rudack, T, Beck, F, Baumeister, W. 登録日 2018-08-20 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.86 Å) 主引用文献 Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6SJQ	1.7-A resolution crystal structure of the N-terminal domain of T. brucei BILBO1 分子名称: Flagellar pocket-related cytoskeletal protein, GLYCEROL 著者 Vidilaseris, K, Dong, G. 登録日 2019-08-13 公開日 2020-01-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.604 Å) 主引用文献 Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding. J.Biol.Chem., 295, 2020
7AVM	Crystal Structure of Pro-Rhodesain C150A 分子名称: Cysteine protease, GLYCEROL 著者 Johe, P, Jaenicke, E, Neuweiler, H, Schirmeister, T, Kersten, C, Hellmich, U. 登録日 2020-11-05 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes. J.Biol.Chem., 296, 2021
6WDP	Interleukin 12 receptor subunit beta-1 分子名称: GLYCEROL, Interleukin-12 receptor subunit beta-1, SULFATE ION 著者 Spangler, J.B, Thomas, C, Jude, K.M, Garcia, K.C. 登録日 2020-04-01 公開日 2021-02-24 最終更新日 2021-12-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells. Cell, 184, 2021
4RHK	Crystal structure of T. brucei arginase-like protein in an oxidized form 分子名称: Arginase, GLYCEROL 著者 Hai, Y, Barrett, M.P, Christianson, D.W. 登録日 2014-10-02 公開日 2014-12-31 最終更新日 2015-02-04 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
7A1I	Crystal structure of the BILBO2/FPC4 complex 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BILBO1_N domain-containing protein, ... 著者 Dong, G. 登録日 2020-08-13 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar. Plos Pathog., 17, 2021
6ZPK	Crystal structure of the unconventional kinetochore protein Trypanosoma brucei KKT4 BRCT domain 分子名称: GLYCEROL, SULFATE ION, Trypanosoma brucei KKT4 463-645 著者 Ludzia, P, Lowe, E.D, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B. 登録日 2020-07-08 公開日 2020-10-21 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein. Structure, 29, 2021
2Q0X	Alpha/Beta hydrolase fold protein of unknown function 分子名称: GLYCEROL, Uncharacterized protein 著者 Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2007-05-22 公開日 2007-06-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function. Acta Crystallogr.,Sect.F, 64, 2008
6T97	Trypanothione Reductase from Leismania infantum in complex with TRL190 分子名称: 4-[1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-4-yl]butan-1-amine, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Carriles, A, Hermoso, J.A. 登録日 2019-10-26 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Scaffold hopping identifies new triazole-and triazolium-based inhibitors of Leishmania infantum Trypanothione Reductase with potent and selective antileishmanial activity To Be Published
4RHI	Crystal structure of SeMet-labeled wild-type T. brucei arginase-like protein in P321 space group 分子名称: Arginase, GLYCEROL 著者 Hai, Y, Barrett, M.P, Christianson, D.W. 登録日 2014-10-02 公開日 2014-12-31 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHL	Crystal structure of T. brucei arginase-like protein triple mutant S149D/R151H/S226D bound with Mn2+ 分子名称: Arginase, GLYCEROL, MANGANESE (II) ION 著者 Hai, Y, Barrett, M.P, Christianson, D.W. 登録日 2014-10-02 公開日 2014-12-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHQ	Crystal structure of T. brucei arginase-like protein double mutant S149D/S153D 分子名称: 1,2-ETHANEDIOL, Arginase, GLYCEROL 著者 Hai, Y, Barrett, M.P, Christianson, D.W. 登録日 2014-10-02 公開日 2014-12-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHM	Crystal structure of T. brucei arginase-like protein quadruple mutant S149D/R151H/S153D/S226D 分子名称: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... 著者 Hai, Y, Barrett, M.P, Christianson, D.W. 登録日 2014-10-02 公開日 2014-12-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
5G57	Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-001 分子名称: (4~{a}~{S},8~{a}~{R})-2-cycloheptyl-4-[4-methoxy-3-[4-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenoxy]butoxy]phenyl]-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-one, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... 著者 Singh, A.K, Brown, D.G. 登録日 2016-05-22 公開日 2017-11-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
7Q1E	CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX 分子名称: Centromere protein J, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Campanacci, V, Gigant, b. 登録日 2021-10-19 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors. Proc.Natl.Acad.Sci.USA, 119, 2022
8D1R	Crystal structure of acetyltransferase Eis from Mycobacterium tuberculosis in complex with inhibitor SGT520 分子名称: 1-{3-[(4-chlorophenyl)methoxy]phenyl}methanamine, GLYCEROL, N-acetyltransferase Eis 著者 Pang, A.H, Punetha, A, Garneau-Tsodikova, S, Tsodikov, O.V. 登録日 2022-05-27 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. Eur.J.Med.Chem., 242, 2022

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