6G04
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![BU of 6g04 by Molmil](/molmil-images/mine/6g04) | NMR Solution Structure of Yeast TSR2(1-152) in Complex with S26A(100-119) | 分子名称: | 40S ribosomal protein S26-A, Pre-rRNA-processing protein TSR2 | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | 登録日 | 2018-03-16 | 公開日 | 2018-09-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun, 9, 2018
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6G7I
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![BU of 6g7i by Molmil](/molmil-images/mine/6g7i) | Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: 49-406 fs state structure | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, ... | 著者 | Nogly, P, Weinert, T, James, D, Cabajo, S, Ozerov, D, Furrer, A, Gashi, D, Borin, V, Skopintsev, P, Jaeger, K, Nass, K, Bath, P, Bosman, R, Koglin, J, Seaberg, M, Lane, T, Kekilli, D, Bruenle, S, Tanaka, T, Wu, W, Milne, C, White, T, Barty, A, Weierstall, U, Panneels, V, Nango, E, Iwata, S, Hunter, M, Schapiro, I, Schertler, G, Neutze, R, Standfuss, J. | 登録日 | 2018-04-06 | 公開日 | 2018-06-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science, 361, 2018
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6FMY
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![BU of 6fmy by Molmil](/molmil-images/mine/6fmy) | IMISX-EP of S-PepTSt | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Di-or tripeptide:H+ symporter, ... | 著者 | Huang, C.-Y, Olieric, V, Howe, N, Warshamanage, R, Weinert, T, Panepucci, E, Vogeley, L, Basu, S, Diederichs, K, Caffrey, M, Wang, M. | 登録日 | 2018-02-02 | 公開日 | 2018-09-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | In situ serial crystallography for rapid de novo membrane protein structure determination. Commun Biol, 1, 2018
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4MF0
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![BU of 4mf0 by Molmil](/molmil-images/mine/4mf0) | ITK kinase domain in complex with benzothiazole inhibitor compound 12a (1S,2S)-2-{4-[(DIMETHYLAMINO)METHYL]PHENYL}-N-[6-(PYRIDIN-3-YL)-1,3-BENZOTHIAZOL-2-YL]CYCLOPROPANECARBOXAMIDE (12a) | 分子名称: | (1S,2S)-2-{4-[(dimethylamino)methyl]phenyl}-N-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide, Tyrosine-protein kinase ITK/TSK | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2013-08-27 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK). Bioorg.Med.Chem.Lett., 23, 2013
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4MF1
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![BU of 4mf1 by Molmil](/molmil-images/mine/4mf1) | ITK kinase domain in complex with benzothiazole inhibitor 12b (1S,2S)-2-{4-[(DIMETHYLAMINO)METHYL]PHENYL}-N-[6-(1H-PYRAZOL-4-YL)-1,3-BENZOTHIAZOL-2-YL]CYCLOPROPANECARBOXAMIDE | 分子名称: | (1S,2S)-2-{4-[(dimethylamino)methyl]phenyl}-N-[6-(1H-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide, Tyrosine-protein kinase ITK/TSK | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2013-08-27 | 公開日 | 2013-11-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.113 Å) | 主引用文献 | Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK). Bioorg.Med.Chem.Lett., 23, 2013
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6G03
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![BU of 6g03 by Molmil](/molmil-images/mine/6g03) | NMR Solution Structure of yeast TSR2(1-152) | 分子名称: | Pre-rRNA-processing protein TSR2 | 著者 | Michel, E, Schuetz, S, Damberger, F.F, Allain, F.H.-T, Panse, V.G. | 登録日 | 2018-03-16 | 公開日 | 2018-09-19 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2. Nat Commun, 9, 2018
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5LII
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![BU of 5lii by Molmil](/molmil-images/mine/5lii) | bacteriophage phi812K1-420 major capsid protein | 分子名称: | Major capsid protein | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5LLJ
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6GO9
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![BU of 6go9 by Molmil](/molmil-images/mine/6go9) | Structure of GFPmut2 crystallized at pH 6 and transferred to pH 7 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Green fluorescent protein | 著者 | Lolli, G, Raboni, S, Pasqualetto, E, Campanini, B, Mozzarelli, A, Bettati, S, Battistutta, R. | 登録日 | 2018-06-01 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.672 Å) | 主引用文献 | Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography. J.Phys.Chem.B, 122, 2018
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4OKW
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![BU of 4okw by Molmil](/molmil-images/mine/4okw) | Crystal structure of W741L-AR-LBD bound with co-regulator peptide | 分子名称: | Androgen receptor, R-BICALUTAMIDE, co-regulator peptide | 著者 | Liu, J.S, Hsu, C.L, Wu, W.G. | 登録日 | 2014-01-23 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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4OTI
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![BU of 4oti by Molmil](/molmil-images/mine/4oti) | Crystal Structure of PRK1 Catalytic Domain in Complex with Tofacitinib | 分子名称: | 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Serine/threonine-protein kinase N1 | 著者 | Chamberlain, P.P, Delker, S, Pagarigan, B, Mahmoudi, A, Jackson, P, Abbassian, M, Muir, J, Raheja, N, Cathers, B. | 登録日 | 2014-02-13 | 公開日 | 2014-08-27 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal Structures of PRK1 in Complex with the Clinical Compounds Lestaurtinib and Tofacitinib Reveal Ligand Induced Conformational Changes. Plos One, 9, 2014
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6H2I
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2ROX
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![BU of 2rox by Molmil](/molmil-images/mine/2rox) | TRANSTHYRETIN (ALSO CALLED PREALBUMIN) COMPLEX WITH THYROXINE (T4) | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, SULFATE ION, TRANSTHYRETIN | 著者 | Wojtczak, A, Cody, V, Luft, J.R, Pangborn, W. | 登録日 | 1996-10-23 | 公開日 | 1997-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution. Acta Crystallogr.,Sect.D, 52, 1996
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5LU7
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![BU of 5lu7 by Molmil](/molmil-images/mine/5lu7) | Heptose isomerase GmhA mutant - D61A | 分子名称: | 1,2-ETHANEDIOL, 7-O-phosphono-D-glycero-alpha-D-manno-heptopyranose, Phosphoheptose isomerase, ... | 著者 | Vivoli, M, Harmer, N.J, Pang, J. | 登録日 | 2016-09-08 | 公開日 | 2017-12-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A half-site multimeric enzyme achieves its cooperativity without conformational changes. Sci Rep, 7, 2017
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6FHT
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![BU of 6fht by Molmil](/molmil-images/mine/6fht) | Crystal structure of an artificial phytochrome regulated adenylate/guanylate cyclase in its dark adapted Pr form | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Adenylate cyclase, DODECAETHYLENE GLYCOL, ... | 著者 | Etzl, S, Winkler, A. | 登録日 | 2018-01-15 | 公開日 | 2018-04-18 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications. J. Biol. Chem., 293, 2018
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6FH8
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![BU of 6fh8 by Molmil](/molmil-images/mine/6fh8) | E. coli surface display of streptavidin for directed evolution of an allylic deallocase | 分子名称: | Streptavidin, biotinylated ruthenium cyclopentadienide | 著者 | Heinisch, T, Schwizer, F, Garabedian, B, Csibra, E, Jeschek, M, Pinheiro Bernhardes, V, Marliere, P, Panke, S, Ward, T.R. | 登録日 | 2018-01-12 | 公開日 | 2018-08-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | E. colisurface display of streptavidin for directed evolution of an allylic deallylase. Chem Sci, 9, 2018
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5NJ2
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![BU of 5nj2 by Molmil](/molmil-images/mine/5nj2) | Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate | 分子名称: | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, ACETATE ION, ... | 著者 | Tassoni, R, Pannu, N.S, Ubbink, M. | 登録日 | 2017-03-27 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Phosphate Promotes the Recovery of Mycobacterium tuberculosis beta-Lactamase from Clavulanic Acid Inhibition. Biochemistry, 56, 2017
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5GTG
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![BU of 5gtg by Molmil](/molmil-images/mine/5gtg) | Crystal structure of onion lachrymatory factor synthase (LFS) containing 1,2-propanediol | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lachrymatory-factor synthase, S-1,2-PROPANEDIOL, ... | 著者 | Arakawa, T, Sato, Y, Takabe, J, Masamura, N, Tsuge, N, Imai, S, Fushinobu, S. | 登録日 | 2016-08-20 | 公開日 | 2017-08-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Dissecting the Stereocontrolled Conversion of Short-Lived Sulfenic Acid by Lachrymatory Factor Synthase Acs Catalysis, 10, 2020
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4MT4
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6G7J
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![BU of 6g7j by Molmil](/molmil-images/mine/6g7j) | Retinal isomerization in bacteriorhodopsin revealed by a femtosecond X-ray laser: 457-646 fs state structure | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, ... | 著者 | Nogly, P, Weinert, T, James, D, Cabajo, S, Ozerov, D, Furrer, A, Gashi, D, Borin, V, Skopintsev, P, Jaeger, K, Nass, K, Bath, P, Bosman, R, Koglin, J, Seaberg, M, Lane, T, Kekilli, D, Bruenle, S, Tanaka, T, Wu, W, Milne, C, White, T, Barty, A, Weierstall, U, Panneels, V, Nango, E, Iwata, S, Hunter, M, Schapiro, I, Schertler, G, Neutze, R, Standfuss, J. | 登録日 | 2018-04-06 | 公開日 | 2018-06-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science, 361, 2018
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6FMS
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![BU of 6fms by Molmil](/molmil-images/mine/6fms) | IMISX-EP of Se-LspA | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Globomycin, Lipoprotein signal peptidase | 著者 | Huang, C.-Y, Olieric, V, Howe, N, Warshamanage, R, Weinert, T, Panepucci, E, Vogeley, L, Basu, S, Diederichs, K, Caffrey, M, Wang, M. | 登録日 | 2018-02-02 | 公開日 | 2018-08-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | In situ serial crystallography for rapid de novo membrane protein structure determination. Commun Biol, 1, 2018
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5NIY
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![BU of 5niy by Molmil](/molmil-images/mine/5niy) | Signal recognition particle-docking protein FtsY | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Signal recognition particle-docking protein FtsY | 著者 | Kempf, G, Stjepanovic, G, Lapouge, K, Sinning, I. | 登録日 | 2017-03-27 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Escherichia coli SRP Receptor Forms a Homodimer at the Membrane. Structure, 26, 2018
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6FUU
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4OK1
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![BU of 4ok1 by Molmil](/molmil-images/mine/4ok1) | Crystal structure of W741L-AR-LBD bound with co-regulator peptide | 分子名称: | Androgen receptor, R-BICALUTAMIDE, co-regulator peptide | 著者 | Liu, J.S, Hsu, C.L, Wu, W.G. | 登録日 | 2014-01-21 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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5LIJ
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![BU of 5lij by Molmil](/molmil-images/mine/5lij) | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | 分子名称: | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | 登録日 | 2016-07-14 | 公開日 | 2017-07-26 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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