PDB: 2225 件ウェブページステータス検索Chemie searchBIRD

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3EKE	Crystal structure of IBV X-domain at pH 5.6 分子名称: L(+)-TARTARIC ACID, Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-19 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
7R3N	mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 3 分子名称: Interleukin-12 subunit beta, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Bloch, Y, Savvides, S.N. 登録日 2022-02-07 公開日 2022-05-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Around she goes: the structure of mouse Interleukin-12 p80 To Be Published
6W4Q	Crystal structure of full-length tailspike protein 2 (TSP2, ORF211) ) from Escherichia coli O157:H7 bacteriophage CAB120 分子名称: 1,2-ETHANEDIOL, CARBONATE ION, CHLORIDE ION, ... 著者 Greenfield, J, Herzberg, O. 登録日 2020-03-11 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7. Sci Rep, 10, 2020
5DRV	Crystal structure of the G3BP2 NTF2-like domain in complex with a peptide 分子名称: Non-structural protein 3, Ras GTPase-activating protein-binding protein 2 著者 Kristensen, O. 登録日 2015-09-16 公開日 2015-10-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide. Biochem.Biophys.Res.Commun., 467, 2015
5MQX	NMR solution structure of macro domain from Venezuelan equine encephalitis virus(VEEV) in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein3 著者 Makrynitsa, G.I, Ntonti, D, Marousis, K.D, Matsoukas, M.T, Papageorgiou, N, Coutard, B, Bentrop, D, Spyroulias, G.A. 登録日 2016-12-21 公開日 2018-07-04 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose. J.Struct.Biol., 206, 2019
1H4J	Methylobacterium extorquens methanol dehydrogenase D303E mutant 分子名称: CALCIUM ION, Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, ... 著者 Mohammed, F, Gill, R, Thompson, D, Cooper, J.B, Wood, S.P, Afolabi, P.R, Anthony, C. 登録日 2001-05-11 公開日 2001-08-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,) Biochemistry, 40, 2001
7PUR	mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 2 分子名称: Interleukin-12 subunit beta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bloch, Y, Savvides, S.N. 登録日 2021-09-30 公開日 2021-11-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Around she goes: the structure of mouse Interleukin-12 p80 To Be Published
6S7J	Native crystal structure of ergothioneine degrading enzyme Ergothionase from Treponema denticola 分子名称: Uncharacterized protein 著者 Leisinger, F, Seebeck, F.P. 登録日 2019-07-05 公開日 2019-07-17 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Mechanism of Ergothionase from Treponema denticola. Chemistry, 25, 2019
6E78	Structure of Human Transthyretin Asp38Ala Mutant in Complex with Diflunisal 分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin 著者 Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2018-07-25 公開日 2019-07-31 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.499 Å) 主引用文献 Structural Variants of Transthyretin To Be Published
1EYU	HIGH RESOLUTION STRUCTURE OF THE PVUII ENDONCULEASE/COGNATE DNA COMPLEX AT PH 4.6 分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), TYPE II RESTRICTION ENZYME PVUII 著者 Horton, J.R, Cheng, X. 登録日 2000-05-09 公開日 2000-07-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 PvuII endonuclease contains two calcium ions in active sites. J.Mol.Biol., 300, 2000
1F0O	PVUII ENDONUCLEASE/COGNATE DNA COMPLEX (GLUTARALDEHYDE-CROSSLINKED CRYSTAL) AT PH 7.5 WITH TWO CALCIUM IONS AT EACH ACTIVE SITE 分子名称: (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C-3'), CALCIUM ION, TYPE II RESTRICTION ENZYME PVUII 著者 Horton, J.R, Cheng, X. 登録日 2000-05-16 公開日 2000-11-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 PvuII endonuclease contains two calcium ions in active sites. J.Mol.Biol., 300, 2000
6E76	Structure of Human Transthyretin Asp38Ala/Thr119Met Mutant 分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ... 著者 Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2018-07-25 公開日 2019-07-31 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Variants of Transthyretin To Be Published
6E75	Structure of Human Transthyretin Asp38Ala Mutant 分子名称: ACETATE ION, Transthyretin 著者 Chung, K, Saelices, L, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2018-07-25 公開日 2019-07-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Variants of Transthyretin To Be Published
6E77	Structure of Human Transthyretin Asp38Ala Mutant in Complex with Tafamidis 分子名称: 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin 著者 Saelices, L, Chung, K, Sawaya, M.R, Cascio, D, Eisenberg, D. 登録日 2018-07-25 公開日 2019-07-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Variants of Transthyretin To Be Published
8K9U	Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 2 (ADKI2) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... 著者 Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. 登録日 2023-08-01 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors Commun Biol, 7, 2024
8K9W	Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 4 (ADKI4) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase, ~{N}2-(2-methoxyphenyl)-~{N}4-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine 著者 Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. 登録日 2023-08-01 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors Commun Biol, 7, 2024
8K9S	Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 1 (ADKI1) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... 著者 Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. 登録日 2023-08-01 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors Commun Biol, 7, 2024
8K9V	Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 3 (ADKI3) 分子名称: GLYCEROL, LYSINE, Lysine--tRNA ligase, ... 著者 Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. 登録日 2023-08-01 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors Commun Biol, 7, 2024
8K9X	Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 5 (ADKI5) 分子名称: (2~{S})-2,6-bis(azanyl)-~{N}-[3-[2-[[4-[(2,5-dimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]phenyl]sulfonylpropyl]hexanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase 著者 Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. 登録日 2023-08-01 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors Commun Biol, 7, 2024
6WX4	Crystal structure of the SARS CoV-2 Papain-like protease in complex with peptide inhibitor VIR251 分子名称: Non-structural protein 3, VIR251, ZINC ION 著者 Lv, Z, Olsen, S.K. 登録日 2020-05-09 公開日 2020-05-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.655 Å) 主引用文献 Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design. Sci Adv, 6, 2020
2QCL	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCM	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP 分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
6XA9	SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide 分子名称: GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
6XAA	SARS CoV-2 PLpro in complex with ubiquitin propargylamide 分子名称: Non-structural protein 3, Ubiquitin-propargylamide, ZINC ION 著者 Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. 登録日 2020-06-04 公開日 2020-06-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2. Embo J., 39, 2020
2QCF	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP 分子名称: 5-FLUORO-URIDINE-5'-MONOPHOSPHATE, GLYCEROL, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008

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