PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

---

2JC0	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264 分子名称: (2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOROMETHYL)BENZOYL]PYRROLIDINE-2,4-DICARBOXYLIC ACID, RNA-DEPENDENT RNA-POLYMERASE 著者 Wonacott, A, Skarzynski, T, Singh, O.M. 登録日 2006-12-18 公開日 2007-02-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. J.Med.Chem., 50, 2007
2JC1	CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223 分子名称: (2S,4S,5R)-1-(4-TERT-BUTYLBENZOYL)-2-ISOBUTYL-5-(1,3-THIAZOL-2-YL)PYRROLIDINE-2,4-DICARBOXYLIC ACID, RNA-DEPENDENT RNA-POLYMERASE 著者 Wonacott, A, Skarzynski, T, Singh, O.M. 登録日 2006-12-18 公開日 2007-02-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. J.Med.Chem., 50, 2007
4GWP	Structure of the Mediator Head Module from S. cerevisiae 分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... 著者 Robinson, P.J.J, Bushnell, D.A, Trnka, M.J, Burlingame, A.L, Kornberg, R.D. 登録日 2012-09-03 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II. Proc.Natl.Acad.Sci.USA, 109, 2012
3NAI	Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase 分子名称: 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... 著者 Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. 登録日 2010-06-02 公開日 2011-06-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
3FRZ	Crystal Structure of HCV NS5B RNA polymerase in complex with PF868554 分子名称: (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, BETA-MERCAPTOETHANOL, N-[(benzyloxy)carbonyl]-L-alpha-glutamyl-N-[(1S)-4-oxo-4-phenyl-1-propylbut-2-en-1-yl]-L-phenylalaninamide, ... 著者 Parge, H.E. 登録日 2009-01-08 公開日 2009-03-10 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. J.Med.Chem., 52, 2009
7B3B	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -3 (structure 1) 分子名称: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*G)-D(P*(RMP))-R(P*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... 著者 Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. 登録日 2020-11-30 公開日 2020-12-23 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
7B3C	Structure of elongating SARS-CoV-2 RNA-dependent RNA polymerase with Remdesivir at position -4 (structure 2) 分子名称: DNA/RNA (5'-R(P*CP*UP*AP*CP*GP*CP*A)-D(P*(RMP))-R(P*GP*UP*G)-3'), Non-structural protein 7, Non-structural protein 8, ... 著者 Kokic, G, Hillen, H.S, Tegunov, D, Dienemann, C, Seitz, F, Schmitzova, J, Farnung, L, Siewert, A, Hoebartner, C, Cramer, P. 登録日 2020-11-30 公開日 2020-12-23 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanism of SARS-CoV-2 polymerase stalling by remdesivir. Nat Commun, 12, 2021
2XUB	Human RPC62 subunit structure 分子名称: DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 著者 Lefevre, S, Legrand, P, Fribourg, S. 登録日 2010-10-18 公開日 2011-03-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription Nat.Struct.Mol.Biol., 18, 2011
2XV4	Structure of Human RPC62 (partial) 分子名称: DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3, PHOSPHATE ION 著者 Lefevre, S, Legrand, P, Fribourg, S. 登録日 2010-10-22 公開日 2011-03-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure-Function Analysis of Hrpc62 Provides Insights Into RNA Polymerase III Transcription Nat.Struct.Mol.Biol., 18, 2011
3OMW	Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II 分子名称: CG14216 著者 Zhang, Y, Zhang, M, Zhang, Y. 登録日 2010-08-27 公開日 2011-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8701 Å) 主引用文献 Crystal structure of Ssu72, an essential eukaryotic phosphatase specific for the C-terminal domain of RNA polymerase II, in complex with a transition state analogue. Biochem.J., 434, 2011
4MIW	High-resolution structure of the N-terminal endonuclease domain of the Lassa virus L polymerase 分子名称: MAGNESIUM ION, RNA-directed RNA polymerase L 著者 Wallat, G.D, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C. 登録日 2013-09-02 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 High-resolution structure of the N-terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions. Plos One, 9, 2014
1YNE	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: APOLIPOPROTEIN B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-24 公開日 2005-02-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
1YNG	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: apolipoprotein B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-24 公開日 2005-02-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
1YNC	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: apolipoprotein B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-24 公開日 2005-02-08 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
1YLG	NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor 分子名称: apolipoprotein B mRNA 著者 Maris, C, Masse, J, Allain, F.H, Chester, A, Navaratnam, N. 登録日 2005-01-19 公開日 2005-02-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the apoB mRNA stem-loop and its interaction with the C to U editing APOBEC1 complementary factor. Rna, 11, 2005
8T9D	CryoEM structure of TR-TRAP 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Asturias, F. 登録日 2023-06-23 公開日 2024-07-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.66 Å) 主引用文献 An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II. Mol.Cell, 2024
4NOI	2.17 Angstrom Crystal Structure of DNA-directed RNA Polymerase Subunit Alpha from Campylobacter jejuni. 分子名称: CHLORIDE ION, DNA-directed RNA polymerase subunit alpha, IODIDE ION, ... 著者 Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2013-11-19 公開日 2013-12-04 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 2.17 Angstrom Crystal Structure of DNA-directed RNA Polymerase Subunit Alpha from Campylobacter jejuni. TO BE PUBLISHED
3FMV	Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. 分子名称: Serine phosphatase of RNA polymerase II CTD 著者 Kuzin, A.P, Chen, Y, Seetharaman, J, Forouhar, F, Chinag, Y, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2008-12-22 公開日 2009-01-06 最終更新日 2017-11-01 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Crystal structure of the serine phosphatase of RNA polymerase II CTD (SSU72 superfamily) from Drosophila melanogaster. Monoclinic crystal form. Northeast Structural Genomics Consortium target FR253. To be Published
2DK5	Solution structure of Winged-Helix domain in RNA polymerase III 39KDa polypeptide 分子名称: DNA-directed RNA polymerase III 39 kDa polypeptide 著者 He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-06 公開日 2006-10-06 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of Winged-Helix domain in RNA polymerase III 39KDa polypeptide To be Published
1F78	SOLUTION STRUCTURE OF RNASE P RNA (M1 RNA) P4 STEM OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT (III) HEXAMINE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-26 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1F79	SOLUTION STRUCTURE OF RNASE P RNA (M1 RNA) P4 STEM C70U MUTANT OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT(III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN MUTANT 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-23 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1F7H	SOLUTION STRUCTURE OF THE RNASE P RNA (M1 RNA) P4 STEM OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT (III) HEXAMINE, NMR, ENSEMBLE OF 11 STRUCTURES 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-27 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1F7I	SOLUTION STRUCTURE OF THE RNASE P RNA (M1 RNA) P4 STEM C70U MUTANT OLIGORIBONUCLEOTIDE COMPLEXED WITH COBALT (III) HEXAMINE ,NMR, ENSEMBLE OF 12 STRUCTURES 分子名称: COBALT HEXAMMINE(III), RNASE P RNA RIBOZYME, P4 DOMAIN 著者 Schmitz, M, Tinoco Jr, I. 登録日 2000-06-27 公開日 2000-10-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA. RNA, 6, 2000
1SKP	NMR STRUCTURE OF D(GCATATGATAG)(DOT)D(CTATCATATGC): A CONSENSUS SEQUENCE FOR PROMOTERS RECOGNIZED BY SIGMA-K RNA POLYMERASE, 4 STRUCTURES 分子名称: SIGMA-K RNA POLYMERASE CONSENSUS SEQUENCE 著者 Tonelli, M, Ragg, E, Bianucci, A.M, Lesiak, K, James, T.L. 登録日 1998-05-20 公開日 1999-01-13 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance structure of d(GCATATGATAG). d(CTATCATATGC): a consensus sequence for promoters recognized by sigma K RNA polymerase. Biochemistry, 37, 1998
4C11	Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region 分子名称: DENGUE VIRUS TYPE 3 RNA DEPENDENT RNA POLYMERASE, ZINC ION 著者 Lim, S.P, Lescar, J. 登録日 2013-08-09 公開日 2013-08-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A Crystal Structure of the Dengue Virus Ns5 Polymerase Delineates Inter-Domain Amino Acids Residues that Enhance its Thermostability and De Novo Initiation Activities. J.Biol.Chem., 288, 2013

<37383940414243444546474849505152>