4UZD
 
 | | SAR156497 an exquisitely selective inhibitor of Aurora kinases | | 分子名称: | AURORA KINASE A, ethyl (9S)-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | | 著者 | Pouzieux, S, Delarbre, L, Crenne, J.Y. | | 登録日 | 2014-09-05 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
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4USD
 | | Human STK10 (LOK) with SB-633825 | | 分子名称: | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine, SERINE/THREONINE-PROTEIN KINASE 10 | | 著者 | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Canning, P, Raynor, J, Bountra, C, Edwards, A.M, Knapp, S. | | 登録日 | 2014-07-07 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Comprehensive Characterization of the Published Kinase Inhibitor Set.
Nat.Biotechnol., 34, 2016
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4UZH
 | | SAR156497 an exquisitely selective inhibitor of Aurora kinases | | 分子名称: | (4S)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b][1,7]naphthyridin-5-one, AURORA 2 KINASE DOMAIN | | 著者 | Pouzieux, S, Maignan, S, Crenne, J.Y. | | 登録日 | 2014-09-05 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
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4USF
 | | Human SLK with SB-440719 | | 分子名称: | 4-[4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl]pyridine, STE20-LIKE SERINE/THREONINE-PROTEIN KINASE | | 著者 | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Bountra, C, Edwards, A.M, Knapp, S. | | 登録日 | 2014-07-07 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Comprehensive Characterization of the Published Kinase Inhibitor Set.
Nat.Biotechnol., 34, 2016
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4WHZ
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4WG7
 | | Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a nano focused beam. | | 分子名称: | CHLORIDE ION, Lysozyme C | | 著者 | Coquelle, N, Brewster, A.S, Kappe, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P. | | 登録日 | 2014-09-18 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams.
Acta Crystallogr.,Sect.D, 71, 2015
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4WLT
 | | High pressure protein crystallography of hen egg white lysozyme at 190 MPa | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Yamada, H, Nagae, T, Watanabe, N. | | 登録日 | 2014-10-08 | | 公開日 | 2015-04-08 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
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4WFU
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4WIH
 | | Crystal structure of cAMP-dependent Protein Kinase A from Cricetulus griseus | | 分子名称: | cAMP Dependent Protein Kinase Inhibitor PKI-tide, cAMP-dependent protein kinase catalytic subunit alpha | | 著者 | Kudlinzki, D, Linhard, V.L, Saxena, K, Dreyer, M, Schwalbe, H. | | 登録日 | 2014-09-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.139 Å) | | 主引用文献 | High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.
Acta Crystallogr.,Sect.F, 71, 2015
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4WM6
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4WG1
 | | Room temperature crystal structure of lysozyme determined by serial synchrotron crystallography (micro focused beam - crystFEL) | | 分子名称: | CHLORIDE ION, Lysozyme C | | 著者 | Coquelle, N, Brewster, A.S, Kapp, U, Shilova, A, Weimhausen, B, Sauter, N.K, Burghammer, M, Colletier, J.P. | | 登録日 | 2014-09-17 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams.
Acta Crystallogr.,Sect.D, 71, 2015
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4WPZ
 | | Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis | | 分子名称: | Cytochrome P450, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H. | | 登録日 | 2014-10-21 | | 公開日 | 2015-04-22 | | 最終更新日 | 2015-04-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A.
Arch.Biochem.Biophys., 575, 2015
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4WM2
 | | High pressure protein crystallography of hen egg white lysozyme at 600 MPa | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Yamada, H, Nagae, T, Watanabe, N. | | 登録日 | 2014-10-08 | | 公開日 | 2015-04-08 | | 最終更新日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
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4WNT
 | | Human Cytochrome P450 2D6 Ajmalicine Complex | | 分子名称: | Ajmalicine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Wang, A, Stout, C.D, Johnson, E.F. | | 登録日 | 2014-10-14 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding.
J.Biol.Chem., 290, 2015
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4WOC
 | | Proteinase-K Post-Surface Acoustic Waves | | 分子名称: | Proteinase K, SULFATE ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WW3
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4WM1
 | | High pressure protein crystallography of hen egg white lysozyme at 500 MPa | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Yamada, H, Nagae, T, Watanabe, N. | | 登録日 | 2014-10-08 | | 公開日 | 2015-04-08 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme
Acta Crystallogr.,Sect.D, 71, 2015
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4WO9
 | | Lysozyme Post-Surface Acoustic Waves | | 分子名称: | Lysozyme C, SODIUM ION | | 著者 | French, J.B. | | 登録日 | 2014-10-15 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves.
Small, 11, 2015
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4WNP
 | | Structure of ULK1 bound to a potent inhibitor | | 分子名称: | GLYCEROL, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1 | | 著者 | Lazarus, M.B, Novotny, C.J, Shokat, K.M. | | 登録日 | 2014-10-14 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors.
Acs Chem.Biol., 10, 2015
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4WQQ
 | | Structure of EPNH mutant of CEL-I | | 分子名称: | CALCIUM ION, Lectin CEL-I, N-acetyl-D-galactosamine-specific C-type, ... | | 著者 | Unno, H, Hatakeyama, T. | | 登録日 | 2014-10-22 | | 公開日 | 2015-04-29 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mannose-recognition mutant of the galactose/N-acetylgalactosamine-specific C-type lectin CEL-I engineered by site-directed mutagenesis.
Biochim.Biophys.Acta, 1850, 2015
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4WTU
 | | Crystal structure of BACE1 in complex with 2-aminooxazoline 3-aza-4-fluoro-xanthene inhibitor 22 | | 分子名称: | (5S)-3-(5,6-dihydro-2H-pyran-3-yl)-1-fluoro-7-(2-fluoropyridin-3-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... | | 著者 | Whittington, D.A, Long, A.M. | | 登録日 | 2014-10-30 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | An Orally Available BACE1 Inhibitor That Affords Robust CNS A beta Reduction without Cardiovascular Liabilities.
Acs Med.Chem.Lett., 6, 2015
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4WFV
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4WFT
 | | Crystal structure of tRNA-dihydrouridine(20) synthase dsRBD domain | | 分子名称: | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | | 著者 | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | | 登録日 | 2014-09-17 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res., 43, 2015
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4WG2
 | | P411BM3-CIS T438S I263F regioselective C-H amination catalyst | | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Hyster, T.K, Farwell, C.C, Buller, A.R, McIntosh, J.A, Arnold, F.H. | | 登録日 | 2014-09-17 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-h amination.
J.Am.Chem.Soc., 136, 2014
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4WL6
 | | Raster-scanning protein crystallography using micro and nano-focused synchrotron beams | | 分子名称: | CHLORIDE ION, Lysozyme C | | 著者 | Coquelle, N, Kapp, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P. | | 登録日 | 2014-10-06 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams.
Acta Crystallogr.,Sect.D, 71, 2015
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