4UZD
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![BU of 4uzd by Molmil](/molmil-images/mine/4uzd) | SAR156497 an exquisitely selective inhibitor of Aurora kinases | 分子名称: | AURORA KINASE A, ethyl (9S)-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | 著者 | Pouzieux, S, Delarbre, L, Crenne, J.Y. | 登録日 | 2014-09-05 | 公開日 | 2014-11-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases. J.Med.Chem., 58, 2015
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4USD
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![BU of 4usd by Molmil](/molmil-images/mine/4usd) | Human STK10 (LOK) with SB-633825 | 分子名称: | 4-{5-(6-methoxynaphthalen-2-yl)-1-methyl-2-[2-methyl-4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl}pyridine, SERINE/THREONINE-PROTEIN KINASE 10 | 著者 | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Canning, P, Raynor, J, Bountra, C, Edwards, A.M, Knapp, S. | 登録日 | 2014-07-07 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016
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4UZH
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![BU of 4uzh by Molmil](/molmil-images/mine/4uzh) | SAR156497 an exquisitely selective inhibitor of Aurora kinases | 分子名称: | (4S)-4-(2-fluorophenyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b][1,7]naphthyridin-5-one, AURORA 2 KINASE DOMAIN | 著者 | Pouzieux, S, Maignan, S, Crenne, J.Y. | 登録日 | 2014-09-05 | 公開日 | 2014-11-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases. J.Med.Chem., 58, 2015
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4USF
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![BU of 4usf by Molmil](/molmil-images/mine/4usf) | Human SLK with SB-440719 | 分子名称: | 4-[4-(6-methoxynaphthalen-2-yl)-1H-imidazol-5-yl]pyridine, STE20-LIKE SERINE/THREONINE-PROTEIN KINASE | 著者 | Elkins, J.M, Salah, E, Szklarz, M, von Delft, F, Bountra, C, Edwards, A.M, Knapp, S. | 登録日 | 2014-07-07 | 公開日 | 2015-07-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Comprehensive Characterization of the Published Kinase Inhibitor Set. Nat.Biotechnol., 34, 2016
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4WHZ
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![BU of 4whz by Molmil](/molmil-images/mine/4whz) | |
4WG7
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![BU of 4wg7 by Molmil](/molmil-images/mine/4wg7) | Room-temperature crystal structure of lysozyme determined by serial synchrotron crystallography using a nano focused beam. | 分子名称: | CHLORIDE ION, Lysozyme C | 著者 | Coquelle, N, Brewster, A.S, Kappe, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P. | 登録日 | 2014-09-18 | 公開日 | 2015-05-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams. Acta Crystallogr.,Sect.D, 71, 2015
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4WLT
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![BU of 4wlt by Molmil](/molmil-images/mine/4wlt) | High pressure protein crystallography of hen egg white lysozyme at 190 MPa | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Yamada, H, Nagae, T, Watanabe, N. | 登録日 | 2014-10-08 | 公開日 | 2015-04-08 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WFU
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4WIH
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![BU of 4wih by Molmil](/molmil-images/mine/4wih) | Crystal structure of cAMP-dependent Protein Kinase A from Cricetulus griseus | 分子名称: | cAMP Dependent Protein Kinase Inhibitor PKI-tide, cAMP-dependent protein kinase catalytic subunit alpha | 著者 | Kudlinzki, D, Linhard, V.L, Saxena, K, Dreyer, M, Schwalbe, H. | 登録日 | 2014-09-25 | 公開日 | 2014-10-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.139 Å) | 主引用文献 | High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus. Acta Crystallogr.,Sect.F, 71, 2015
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4WM6
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4WG1
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![BU of 4wg1 by Molmil](/molmil-images/mine/4wg1) | Room temperature crystal structure of lysozyme determined by serial synchrotron crystallography (micro focused beam - crystFEL) | 分子名称: | CHLORIDE ION, Lysozyme C | 著者 | Coquelle, N, Brewster, A.S, Kapp, U, Shilova, A, Weimhausen, B, Sauter, N.K, Burghammer, M, Colletier, J.P. | 登録日 | 2014-09-17 | 公開日 | 2015-05-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams. Acta Crystallogr.,Sect.D, 71, 2015
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4WPZ
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![BU of 4wpz by Molmil](/molmil-images/mine/4wpz) | Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis | 分子名称: | Cytochrome P450, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H. | 登録日 | 2014-10-21 | 公開日 | 2015-04-22 | 最終更新日 | 2015-04-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch.Biochem.Biophys., 575, 2015
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4WM2
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![BU of 4wm2 by Molmil](/molmil-images/mine/4wm2) | High pressure protein crystallography of hen egg white lysozyme at 600 MPa | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Yamada, H, Nagae, T, Watanabe, N. | 登録日 | 2014-10-08 | 公開日 | 2015-04-08 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WNT
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![BU of 4wnt by Molmil](/molmil-images/mine/4wnt) | Human Cytochrome P450 2D6 Ajmalicine Complex | 分子名称: | Ajmalicine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Wang, A, Stout, C.D, Johnson, E.F. | 登録日 | 2014-10-14 | 公開日 | 2015-01-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
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4WOC
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![BU of 4woc by Molmil](/molmil-images/mine/4woc) | Proteinase-K Post-Surface Acoustic Waves | 分子名称: | Proteinase K, SULFATE ION | 著者 | French, J.B. | 登録日 | 2014-10-15 | 公開日 | 2015-02-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. Small, 11, 2015
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4WW3
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4WM1
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![BU of 4wm1 by Molmil](/molmil-images/mine/4wm1) | High pressure protein crystallography of hen egg white lysozyme at 500 MPa | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Yamada, H, Nagae, T, Watanabe, N. | 登録日 | 2014-10-08 | 公開日 | 2015-04-08 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
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4WO9
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![BU of 4wo9 by Molmil](/molmil-images/mine/4wo9) | Lysozyme Post-Surface Acoustic Waves | 分子名称: | Lysozyme C, SODIUM ION | 著者 | French, J.B. | 登録日 | 2014-10-15 | 公開日 | 2015-02-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves. Small, 11, 2015
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4WNP
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![BU of 4wnp by Molmil](/molmil-images/mine/4wnp) | Structure of ULK1 bound to a potent inhibitor | 分子名称: | GLYCEROL, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1 | 著者 | Lazarus, M.B, Novotny, C.J, Shokat, K.M. | 登録日 | 2014-10-14 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors. Acs Chem.Biol., 10, 2015
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4WQQ
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![BU of 4wqq by Molmil](/molmil-images/mine/4wqq) | Structure of EPNH mutant of CEL-I | 分子名称: | CALCIUM ION, Lectin CEL-I, N-acetyl-D-galactosamine-specific C-type, ... | 著者 | Unno, H, Hatakeyama, T. | 登録日 | 2014-10-22 | 公開日 | 2015-04-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mannose-recognition mutant of the galactose/N-acetylgalactosamine-specific C-type lectin CEL-I engineered by site-directed mutagenesis. Biochim.Biophys.Acta, 1850, 2015
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4WTU
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![BU of 4wtu by Molmil](/molmil-images/mine/4wtu) | Crystal structure of BACE1 in complex with 2-aminooxazoline 3-aza-4-fluoro-xanthene inhibitor 22 | 分子名称: | (5S)-3-(5,6-dihydro-2H-pyran-3-yl)-1-fluoro-7-(2-fluoropyridin-3-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... | 著者 | Whittington, D.A, Long, A.M. | 登録日 | 2014-10-30 | 公開日 | 2015-03-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An Orally Available BACE1 Inhibitor That Affords Robust CNS A beta Reduction without Cardiovascular Liabilities. Acs Med.Chem.Lett., 6, 2015
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4WFV
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4WFT
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![BU of 4wft by Molmil](/molmil-images/mine/4wft) | Crystal structure of tRNA-dihydrouridine(20) synthase dsRBD domain | 分子名称: | tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | 著者 | Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D. | 登録日 | 2014-09-17 | 公開日 | 2015-10-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | An extended dsRBD is required for post-transcriptional modification in human tRNAs. Nucleic Acids Res., 43, 2015
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4WG2
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![BU of 4wg2 by Molmil](/molmil-images/mine/4wg2) | P411BM3-CIS T438S I263F regioselective C-H amination catalyst | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Hyster, T.K, Farwell, C.C, Buller, A.R, McIntosh, J.A, Arnold, F.H. | 登録日 | 2014-09-17 | 公開日 | 2014-11-05 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Enzyme-controlled nitrogen-atom transfer enables regiodivergent C-h amination. J.Am.Chem.Soc., 136, 2014
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4WL6
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![BU of 4wl6 by Molmil](/molmil-images/mine/4wl6) | Raster-scanning protein crystallography using micro and nano-focused synchrotron beams | 分子名称: | CHLORIDE ION, Lysozyme C | 著者 | Coquelle, N, Kapp, U, Shilova, A, Weinhausen, B, Burghammer, M, Colletier, J.P. | 登録日 | 2014-10-06 | 公開日 | 2015-05-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Raster-scanning serial protein crystallography using micro- and nano-focused synchrotron beams. Acta Crystallogr.,Sect.D, 71, 2015
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