6AVD
| |
6ATN
| |
4LFQ
| High resolution x-ray crystal structure of L-ShK toxin | 分子名称: | Potassium channel toxin ShK | 著者 | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | 登録日 | 2013-06-27 | 公開日 | 2013-08-14 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.059 Å) | 主引用文献 | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
|
|
2L4R
| NMR solution structure of the N-terminal PAS domain of hERG | 分子名称: | Potassium voltage-gated channel subfamily H member 2 | 著者 | Gayen, N, Li, Q, Chen, A.S, Huang, Q, Raida, M, Kang, C. | 登録日 | 2010-10-13 | 公開日 | 2010-12-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of the N-terminal domain of hERG and its interaction with the S4-S5 linker. Biochem.Biophys.Res.Commun., 403, 2010
|
|
2P7T
| Crystal Structure of KcsA mutant | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB-A, FAB-B, ... | 著者 | Cordero-Morales, J.F, Vishwanath, J, Lewis, A, Valeria, V.R, Cortes, D.M, Roux, B, Perozo, E. | 登録日 | 2007-03-20 | 公開日 | 2007-10-09 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal Structure of KcsA mutant To be Published
|
|
9BC6
| HCN1 M305L with propofol | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,6-BIS(1-METHYLETHYL)PHENOL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | 著者 | Kim, E.D, Nimigean, C.M. | 登録日 | 2024-04-07 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature, 632, 2024
|
|
9BC7
| HCN1 M305L holo | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | 著者 | Kim, E.D, Nimigean, C.M. | 登録日 | 2024-04-08 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants. Nature, 632, 2024
|
|
4X8A
| NavMS pore and C-terminal domain grown from protein purified in LiCl | 分子名称: | HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
|
|
4X88
| E178D Selectivity filter mutant of NavMS voltage-gated pore | 分子名称: | HEGA-10, Ion transport protein, PENTAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-02-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
|
|
7UW5
| |
7UX1
| EcMscK in an Open Conformation | 分子名称: | Mechanosensitive channel MscK | 著者 | Mount, J.W, Yuan, P. | 登録日 | 2022-05-04 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel. Nat Commun, 13, 2022
|
|
1KXM
| Crystal structure of Cytochrome c Peroxidase with a Proposed Electron Transfer Pathway Excised to Form a Ligand Binding Channel. | 分子名称: | BENZIMIDAZOLE, Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Rosenfeld, R.J, Hayes, A.M.A, Musah, R.A, Goodin, D.B. | 登録日 | 2002-02-01 | 公開日 | 2002-03-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Excision of a proposed electron transfer pathway in cytochrome c peroxidase and its replacement by a ligand-binding channel. Protein Sci., 11, 2002
|
|
7BYM
| Cryo-EM structure of human KCNQ4 with retigabine | 分子名称: | Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, POTASSIUM ION, ... | 著者 | Shen, H, Li, T, Yue, Z. | 登録日 | 2020-04-23 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Mol.Cell, 81, 2021
|
|
7BYL
| Cryo-EM structure of human KCNQ4 | 分子名称: | Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, POTASSIUM ION, ... | 著者 | Shen, H, Li, T, Yue, Z. | 登録日 | 2020-04-23 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Mol.Cell, 81, 2021
|
|
7BYN
| Cryo-EM structure of human KCNQ4 with linopirdine | 分子名称: | 1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one, Calmodulin-3, Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, ... | 著者 | Shen, H, Li, T, Yue, Z. | 登録日 | 2020-04-23 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Mol.Cell, 81, 2021
|
|
6EIG
| Crystal structure of N24Q/C128T mutant of Channelrhodopsin 2 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, EICOSANE, ... | 著者 | Kovalev, K, Borshchevskiy, V, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. | 登録日 | 2017-09-19 | 公開日 | 2017-12-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
|
|
3EYW
| Crystal structure of the C-terminal domain of E. coli KefC in complex with KefF | 分子名称: | C-terminal domain of Glutathione-regulated potassium-efflux system protein kefC fused to full length Glutathione-regulated potassium-efflux system ancillary protein kefF, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | 著者 | Roosild, T.P. | 登録日 | 2008-10-22 | 公開日 | 2009-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | KTN (RCK) Domains Regulate K(+) Channels and Transporters by Controlling the Dimer-Hinge Conformation. Structure, 17, 2009
|
|
8H86
| Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 in lipid nanodisc | 分子名称: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR1, PALMITIC ACID, ... | 著者 | Tajima, S, Kim, Y, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E. | 登録日 | 2022-10-21 | 公開日 | 2023-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell, 186, 2023
|
|
8H87
| Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR2 in lipid nanodisc | 分子名称: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR2, PALMITIC ACID, ... | 著者 | Tajima, S, Kim, Y, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E. | 登録日 | 2022-10-21 | 公開日 | 2023-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell, 186, 2023
|
|
8IU0
| Cryo-EM structure of the potassium-selective channelrhodopsin HcKCR1 H225F mutant in lipid nanodisc | 分子名称: | (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, HcKCR1, PALMITIC ACID, ... | 著者 | Tajima, S, Kim, Y, Nakamura, S, Yamashita, K, Fukuda, M, Deisseroth, K, Kato, H.E. | 登録日 | 2023-03-23 | 公開日 | 2023-09-06 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.66 Å) | 主引用文献 | Structural basis for ion selectivity in potassium-selective channelrhodopsins. Cell, 186, 2023
|
|
6EID
| Crystal structure of wild-type Channelrhodopsin 2 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Archaeal-type opsin 2, PHOSPHATE ION, ... | 著者 | Borshchevskiy, V, Kovalev, K, Volkov, O, Polovinkin, V, Marin, E, Balandin, T, Astashkin, R, Bamann, C, Bueldt, G, Willlbold, D, Popov, A, Bamberg, E, Gordeliy, V. | 登録日 | 2017-09-19 | 公開日 | 2017-12-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural insights into ion conduction by channelrhodopsin 2. Science, 358, 2017
|
|
7BGY
| Cryo-EM Structure of KdpFABC in E2Pi state with MgF4 | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, MAGNESIUM ION, ... | 著者 | Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L. | 登録日 | 2021-01-09 | 公開日 | 2021-01-27 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for potassium transport in prokaryotes by KdpFABC. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
2I2R
| Crystal structure of the KChIP1/Kv4.3 T1 complex | 分子名称: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | 著者 | Findeisen, F, Pioletti, M, Minor Jr, D.L. | 登録日 | 2006-08-16 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer Nat.Struct.Mol.Biol., 13, 2006
|
|
5VMS
| CryoEM structure of Xenopus KCNQ1 channel | 分子名称: | CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 1 | 著者 | Mackinnon, R, Sun, J. | 登録日 | 2017-04-28 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome. Cell, 169, 2017
|
|
7Y1J
| Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
|
|