PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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4WSB	Bat Influenza A polymerase with bound vRNA promoter 分子名称: Influenza A polymerase vRNA promoter 3' end, Influenza A polymerase vRNA promoter 5' end, PHOSPHATE ION, ... 著者 Cusack, S, Pflug, A, Guilligay, D, Reich, S. 登録日 2014-10-26 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
4WRT	Crystal structure of Influenza B polymerase with bound vRNA promoter (form FluB2) 分子名称: Influenza virus polymerase vRNA promoter 3' end, Influenza virus polymerase vRNA promoter 5' end, PA, ... 著者 Reich, S, Guilligay, D, Pflug, A, Cusack, S. 登録日 2014-10-25 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into cap-snatching and RNA synthesis by influenza polymerase. Nature, 516, 2014
5MSG	Influenza B polymerase bound to vRNA promoter and capped RNA primer 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Cusack, S, Guilligay, D. 登録日 2017-01-04 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase. Nucleic Acids Res., 45, 2017
8RN1	Influenza B polymerase, monomeric encapsidase with 5' cRNA hook bound 分子名称: 5' cRNA hook (1-12), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN3	Pseudo-symmetrical influenza B polymerase apo-dimer, encapsidase moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.78 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN4	Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(T) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RNB	Influenza B polymerase, encapsidase plus 627(R) / human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RNC	Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement) 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.52 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN5	Pseudo-symmetrical influenza B polymerase apo-dimer, ENDO(R) moiety (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN7	Pseudo-symmetrical influenza B polymerase apo-dimer, core-only moeity (from "Influenza B polymerase pseudo-symmetrical dimer" | Local refinement) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN8	Influenza B polymerase pseudo-symmetrical apo-dimer (FluPol(E)|FluPol(S)) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RMR	Influenza polymerase A/H7N9-4M replication complex, an asymmetric polymerase dimer bound to human ANP32A 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, MAGNESIUM ION, Polymerase acidic protein, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-08 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RMS	Influenza polymerase A/H7N9-4M replicase minus 627(R) (from "Influenza polymerase A/H7N9-4M replication complex" | Local refinement) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-08 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
9BZ0	Structure of an STK19-containing TC-NER complex 分子名称: DET1- and DDB1-associated protein 1, DNA (35-MER), DNA (49-MER), ... 著者 Mevissen, T.E.T, Kuemmecke, M, Farnung, L, Walter, J.C. 登録日 2024-05-24 公開日 2024-12-25 最終更新日 2025-01-15 実験手法 ELECTRON MICROSCOPY (1.9 Å) 主引用文献 STK19 positions TFIIH for cell-free transcription-coupled DNA repair. Cell, 187, 2024
6T0S	Bat Influenza A polymerase stuttering complex using 44-mer vRNA template with intact oligo(U) sequence 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Wandzik, J.M, Kouba, T, Cusack, S. 登録日 2019-10-03 公開日 2020-04-15 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
6SZU	Bat Influenza A polymerase pre-termination complex with pyrophosphate using 44-mer vRNA template with mutated oligo(U) sequence 分子名称: 5-oxidanyl-4-oxidanylidene-1-[(1-pyrrolo[2,3-b]pyridin-1-ylcyclopentyl)methyl]pyridine-3-carboxylic acid, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Wandzik, J.M, Kouba, T, Cusack, S. 登録日 2019-10-02 公開日 2020-04-15 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.41 Å) 主引用文献 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
8RMP	Influenza polymerase A/H7N9-4M (ENDO(R) | Core1) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-08 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.77 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RMQ	Influenza polymerase A/H7N9-4M (ENDO(R) | Core2) 分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-08 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
8RN0	Influenza polymerase A/H7N9-4M encapsidase plus 627(R) / human ANP32A (from "Influenza polymerase A/H7N9-4M replication complex" | Local refinement) 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
6GOV	Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX 分子名称: 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... 著者 Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. 登録日 2018-06-04 公開日 2019-02-13 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
6T0N	Bat Influenza A polymerase pre-initiation complex 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Wandzik, J.M, Kouba, T, Cusack, S. 登録日 2019-10-03 公開日 2020-04-15 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
4WTD	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH ADP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AUAAAUUU 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MANGANESE (II) ION, ... 著者 Edwards, T.E, Fox III, D, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTF	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH GS-639475, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU 分子名称: 2'-C-methyluridine 5'-(trihydrogen diphosphate), CHLORIDE ION, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C, Mcgrath, M.E. 登録日 2014-10-30 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTA	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH UDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-CAAAAUUU 分子名称: CHLORIDE ION, MANGANESE (II) ION, RNA PRIMER TEMPLATE CAAAAUUU, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015
4WTC	CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH S15G E86Q E87Q C223H V321I MUTATIONS AND DELTA8 BETA HAIRPIN LOOP DELETION IN COMPLEX WITH CDP, MN2+ AND SYMMETRICAL PRIMER TEMPLATE 5'-AGAAAUUU 分子名称: CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... 著者 Edwards, T.E, Appleby, T.C. 登録日 2014-10-29 公開日 2015-02-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for RNA replication by the hepatitis C virus polymerase. Science, 347, 2015

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