PDB: 8852 件ウェブページステータス検索Chemie searchBIRD

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5M9D	Solution structure of Rtt103 CTD-interacting domain bound to a Ser2Ser7 phosphorylated CTD peptide 分子名称: Regulator of Ty1 transposition protein 103, THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER-PRO-SEP-TYR-SEP-PRO-THR-SER 著者 Jasnovidova, O, Kubicek, K, Stefl, R. 登録日 2016-11-01 公開日 2017-10-11 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of the RNAPII CTDsome with Rtt103. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6MFN	Human Argonaute2-miR-27a bound to HSUR1 target RNA 分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-09-11 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MFR	Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3) 分子名称: PHENOL, PHOSPHATE ION, Protein argonaute-2, ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-09-12 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MDZ	Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2) 分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-09-05 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
3OTC	Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II 分子名称: tRNA(His) guanylyltransferase 著者 Hyde, S.J, Eckenroth, B.E, Doublie, S. 登録日 2010-09-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 tRNAHis guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases. Proc.Natl.Acad.Sci.USA, 107, 2010
7OM7	Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... 著者 Ferrero, D.S, Falqui, M, Verdaguer, N. 登録日 2021-05-21 公開日 2021-07-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
6K32	RdRp complex 分子名称: 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ... 著者 Li, X.W. 登録日 2019-05-16 公開日 2019-11-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis. J.Mol.Biol., 432, 2020
7QDY	RNA-bound human SKI complex 分子名称: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... 著者 Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. 登録日 2021-12-01 公開日 2022-02-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
4OI4	Protein complex of Clp1 bound to ATP and Mg2+ with Pcf11deltaN454deltaC563 of S. cerevisiae 分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. 登録日 2014-01-18 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
5OMQ	Ternary complex of 9N DNA polymerase in the replicative state with three metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA Primer, DNA Template, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
5OMV	Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ... 著者 Betz, K, Marx, A, Diederichs, K. 登録日 2017-08-01 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
4L87	Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution 分子名称: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Xu, X, Yang, X.-L. 登録日 2013-06-16 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.897 Å) 主引用文献 Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes. Structure, 21, 2013
2M23	NMR solution structure of the d3'-hairpin of the group II intron Sc.ai5gamma including EBS1 bound to IBS1 分子名称: RNA (29-MER), RNA_(5'-R(*CP*AP*GP*UP*GP*UP*C)-3')_ 著者 Kruschel, D, Skilandat, M, Sigel, R.K.O. 登録日 2012-12-12 公開日 2013-12-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition. Rna, 20, 2014
3JSB	Crystal structure of the N-terminal domain of the Lymphocytic Choriomeningitis Virus L protein 分子名称: RNA-directed RNA polymerase 著者 Morin, B, Jamal, S, Ferron, F.P, Coutard, B, Bricogne, G, Canard, B, Vonrhein, C, Marseilles Structural Genomics Program @ AFMB (MSGP) 登録日 2009-09-10 公開日 2010-09-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription Plos Pathog., 6, 2010
8PJJ	Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7UUC RNA 著者 Jagtap, P.K.A, Hennig, J. 登録日 2023-06-23 公開日 2023-11-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8PJB	Cryo-EM structure of MLE in complex with UUC RNA and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2023-06-23 公開日 2023-11-01 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
3LLM	Crystal Structure Analysis of a RNA Helicase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, CACODYLATE ION, ... 著者 Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) 登録日 2010-01-29 公開日 2010-05-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein. J.Mol.Biol., 400, 2010
4PTF	Ternary crystal structure of yeast DNA polymerase epsilon with template G 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', ... 著者 Jain, R, Rajashankar, K.R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. 登録日 2014-03-10 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.809 Å) 主引用文献 Crystal Structure of Yeast DNA Polymerase epsilon Catalytic Domain. Plos One, 9, 2014
3MF5	Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor 分子名称: 3-[2-(trans-4-methylcyclohexyl)phenyl]-5-phenylthiophene-2-carboxylic acid, GLYCEROL, RNA-directed RNA polymerase 著者 Harris, S.F, Tavares, G, Ghate, M. 登録日 2010-04-01 公開日 2010-07-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cyclic amide bioisosterism: Strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
4AWM	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with (-)-epigallocatechin gallate from green tea 分子名称: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, MANGANESE (II) ION, POLYMERASE PA 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-06-04 公開日 2012-08-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
4AWK	Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 1 分子名称: (2Z)-4-[(3S)-1-(benzylsulfonyl)-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA 著者 Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. 登録日 2012-06-04 公開日 2012-08-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
7CKL	Structure of Lassa virus polymerase bound to Z matrix protein 分子名称: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... 著者 Xu, X, Peng, R, Peng, Q, Shi, Y. 登録日 2020-07-17 公開日 2021-05-05 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals Nat Microbiol, 6, 2021
7CKM	Structure of Machupo virus polymerase bound to Z matrix protein (monomeric complex) 分子名称: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... 著者 Xu, X, Peng, R, Peng, Q, Shi, Y. 登録日 2020-07-17 公開日 2021-05-05 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals Nat Microbiol, 6, 2021
6X43	Mfd-bound E.coli RNA polymerase elongation complex - II state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. 登録日 2020-05-22 公開日 2021-02-03 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
7ML8	The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with SJ001023038 分子名称: 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-phenyl-1,6-dihydropyrimidine-4-carboxamide, GLUTAMIC ACID, Hexa Vinylpyrrolidone K15, ... 著者 Cuypers, M.G, Slavish, P.J, Yun, M.K, Dubois, R, Rankovic, Z, White, S.W. 登録日 2021-04-27 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with St Jude compound AC067-19 To Be Published

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