PDB: 1682 件ウェブページステータス検索Chemie searchBIRD

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2FJE	adenosine-5-phosphosulfate reductase oxidized state 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, adenylylsulfate reductase, ... 著者 Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. 登録日 2006-01-02 公開日 2006-03-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
5C0N	Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease 分子名称: Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ... 著者 Doyle, C. 登録日 2015-06-12 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015
2FJD	adenosine-5-phosphosulfate reductase in complex with sulfite (covalent adduct) 分子名称: (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, IRON/SULFUR CLUSTER, adenylylsulfate reductase, ... 著者 Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. 登録日 2006-01-02 公開日 2006-03-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006
7NV1	Human Pol Kappa holoenzyme with Ub-PCNA 分子名称: DNA Primer, DNA Template, DNA polymerase kappa, ... 著者 Lancey, C, De Biasio, A, Hamdan, S.M. 登録日 2021-03-15 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
7NV0	Human Pol Kappa holoenzyme with wt PCNA 分子名称: DNA Primer, DNA Template, DNA polymerase kappa, ... 著者 Lancey, C, De Biasio, A, Hamdan, S.M. 登録日 2021-03-15 公開日 2021-11-10 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure of human Pol kappa bound to DNA and mono-ubiquitylated PCNA. Nat Commun, 12, 2021
2GPL	TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors 分子名称: BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ... 著者 Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M. 登録日 2006-04-18 公開日 2006-07-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome. Chem.Biol., 13, 2006
2HPM	Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III 分子名称: CHLORIDE ION, DNA Polymerase III alpha subunit, MAGNESIUM ION, ... 著者 Bailey, S, Wing, R.A, Steitz, T.A. 登録日 2006-07-17 公開日 2006-09-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases. Cell(Cambridge,Mass.), 126, 2006
2HQA	Crystal structure of the catalytic alpha subunit of E. Coli replicative DNA polymerase III 分子名称: DNA polymerase III alpha subunit, PHOSPHATE ION 著者 Lamers, M.H, Georgescu, R.E, Lee, S.G, O'Donnell, M, Kuriyan, J. 登録日 2006-07-18 公開日 2006-09-19 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III. Cell(Cambridge,Mass.), 126, 2006
5UJM	Structure of the active form of human Origin Recognition Complex and its ATPase motor module 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... 著者 Tocilj, A, On, K, Yuan, Z, Sun, J, Elkayam, E, Li, H, Stillman, B, Joshua-Tor, L. 登録日 2017-01-18 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (18 Å) 主引用文献 Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
5CDH	Structure of Legionella pneumophila Histidine Acid Phosphatase complexed with L(+)-tartrate 分子名称: L(+)-TARTARIC ACID, Major acid phosphatase, PENTAETHYLENE GLYCOL 著者 Tanner, J.J. 登録日 2015-07-04 公開日 2016-01-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Crystal structure and tartrate inhibition of Legionella pneumophila histidine acid phosphatase. Arch.Biochem.Biophys., 585, 2015
2GTT	Crystal structure of the rabies virus nucleoprotein-RNA complex 分子名称: Nucleoprotein, PHOSPHATE ION, RNA (99-MER) 著者 Albertini, A.A.V, Wernimont, A.K, Muziol, T, Ravelli, R.B.G, Weissenhorn, W, Ruigrok, R.W.H. 登録日 2006-04-28 公開日 2006-09-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex Science, 313, 2006
5UJ7	Structure of the active form of human Origin Recognition Complex ATPase motor module, complex subunitS 1, 4, 5 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ... 著者 Tocilj, A, Elkayam, E, On, K.F, Joshua-Tor, L. 登録日 2017-01-17 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.394 Å) 主引用文献 Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
5V7L	PCNA mutant R61A/D63A Protein Defective in Gene Silencing 分子名称: Proliferating cell nuclear antigen 著者 Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M. 登録日 2017-03-20 公開日 2018-03-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring. PLoS ONE, 13, 2018
2HNH	Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III 分子名称: DNA polymerase III alpha subunit, PHOSPHATE ION 著者 Meindert, M.H, Georgescu, R.E, Lee, S, O'Donnell, M, Kuriyan, J. 登録日 2006-07-12 公開日 2006-09-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the Catalytic alpha Subunit of E. coli Replicative DNA Polymerase III. Cell(Cambridge,Mass.), 126, 2006
2HPI	Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III 分子名称: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ... 著者 Bailey, S, Wing, R.A, Steitz, T.A. 登録日 2006-07-17 公開日 2006-09-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases. Cell(Cambridge,Mass.), 126, 2006
7OZN	RNA Polymerase II dimer (Class 1) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Dienemann, C, Cramer, P. 登録日 2021-06-28 公開日 2021-10-06 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
7OZP	RNA Polymerase II dimer (Class 3) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Dienemann, C, Cramer, P. 登録日 2021-06-28 公開日 2021-10-06 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
7OOP	Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) 分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-28 公開日 2021-10-06 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OZO	RNA Polymerase II dimer (Class 2) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Aibara, S, Dienemann, C, Cramer, P. 登録日 2021-06-28 公開日 2021-10-06 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of an inactive RNA polymerase II dimer. Nucleic Acids Res., 49, 2021
7OO3	Pol II-CSB-CSA-DDB1-UVSSA (Structure1) 分子名称: CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-26 公開日 2021-10-06 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OPD	Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) 分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-31 公開日 2021-10-06 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OOB	Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-27 公開日 2021-10-13 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OPC	Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) 分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ... 著者 Kokic, G, Cramer, P. 登録日 2021-05-31 公開日 2021-10-13 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of human transcription-DNA repair coupling. Nature, 598, 2021
7OTO	The structure of MutS bound to two molecules of AMPPNP 分子名称: DNA mismatch repair protein MutS, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. 登録日 2021-06-10 公開日 2022-01-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022
7OU4	The structure of MutS bound to one molecule of ATP and one molecule of ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein MutS, ... 著者 Lamers, M.H, Borsellini, A, Friedhoff, P, Kunetsky, V. 登録日 2021-06-11 公開日 2022-01-12 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryogenic electron microscopy structures reveal how ATP and DNA binding in MutS coordinates sequential steps of DNA mismatch repair. Nat.Struct.Mol.Biol., 29, 2022

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