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6QE4
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Re-refinement of 5OLI human IBA57-I3C
分子名称: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Putative transferase CAF17, mitochondrial
著者Calderone, V, Ciofi-Baffoni, S, Gourdoupis, S, Banci, L, Nasta, V.
登録日2019-01-04
公開日2019-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献In-house high-energy-remote SAD phasing using the magic triangle: how to tackle the P1 low symmetry using multiple orientations of the same crystal of human IBA57 to increase the multiplicity.
Acta Crystallogr D Struct Biol, 75, 2019
7TC1
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BU of 7tc1 by Molmil
Crystal structure of D179N KPC-2 beta-lactamase in complex with vaborbactam
分子名称: Carbapenem-hydrolyzing beta-lactamase KPC, PHOSPHATE ION, Vaborbactam
著者van den Akker, F, Alsenani, T.
登録日2021-12-22
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural Characterization of the D179N and D179Y Variants of KPC-2 beta-Lactamase: Omega-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam.
Antimicrob.Agents Chemother., 66, 2022
6QBQ
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BU of 6qbq by Molmil
structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S200A S203A
分子名称: Cell wall assembly regulator SMI1
著者Guillien, M, Batista, M, Francois, J.M, Mourey, L, Maveyraud, L, Zerbib, D.
登録日2018-12-21
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献structure of the core domaine of Knr4, an intrinsically disordered protein from Saccharomyces cerevisiae - mutant S200A S203A
To Be Published
7TET
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BU of 7tet by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.45 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7SWY
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2.6 A structure of a 40-601[TA-rich+1]-40 nucleosome
分子名称: DNA Guide Strand, DNA Tracking Strand, Histone H2A, ...
著者Nodelman, I.M, Bowman, G.D, Armache, J.-P.
登録日2021-11-21
公開日2022-03-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
6QC3
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Ovine respiratory supercomplex I+III2 open class 1
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein, ...
著者Letts, J.A, Sazanov, L.A.
登録日2018-12-26
公開日2019-08-21
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structures of Respiratory Supercomplex I+III2Reveal Functional and Conformational Crosstalk.
Mol.Cell, 75, 2019
6QEK
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BU of 6qek by Molmil
Putative membrane tansporter, magnetosome protein MamM CTD [Desulfamplus magnetovallimortis BW-1]
分子名称: Magnetosome protein
著者Keren, N.K, Zarivach, R.Z.
登録日2019-01-08
公開日2019-01-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Putative membrane tansporter, magnetosome protein MamM CTD [Desulfamplus magnetovallimortis BW-1]
To Be Published
7SZT
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BU of 7szt by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in low pH (protonated state)
分子名称: Dodecyldimethylphosphine oxide, L10 monobody, Multidrug resistance protein, ...
著者Kermani, A.A, Stockbridge, R.B, Burata, O.E.
登録日2021-11-29
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates.
Elife, 11, 2022
7TEQ
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BU of 7teq by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (7.51 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
6QEN
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BU of 6qen by Molmil
Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the 3-Oxo-beta-Sultam inhibitor LMC240
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-[[1-[(4-bromophenyl)methyl]-1,2,3-triazol-4-yl]methylamino]-2-methyl-1-oxidanylidene-propane-2-sulfonic acid, Chymotrypsin-like elastase family member 1, ...
著者Brito, J.A, Almeida, V.T, Carvalho, L.M, Moreira, R, Archer, M.
登録日2019-01-08
公開日2020-03-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.195 Å)
主引用文献3-Oxo-beta-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling.
Acs Chem.Biol., 15, 2020
7SSU
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BU of 7ssu by Molmil
Structure of EmrE-D3 mutant in complex with monobody L10 and methyltriphenylphosphonium
分子名称: L10 monobody, Multidrug transporter EmrE, methyltriphenylphosphonium
著者Kermani, A.A, Stockbridge, R.B.
登録日2021-11-11
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates.
Elife, 11, 2022
6QEX
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BU of 6qex by Molmil
Nanodisc reconstituted human ABCB1 in complex with UIC2 fab and taxol
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Alam, A, Locher, K.P.
登録日2019-01-08
公開日2019-02-27
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.
Science, 363, 2019
7SMM
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BU of 7smm by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in apo form
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
登録日2021-10-26
公開日2022-03-09
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7TDJ
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BU of 7tdj by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
6QFP
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BU of 6qfp by Molmil
Solution NMR ensemble for MlbQ at 298K compiled using the CoMAND method
分子名称: Putative lipoprotein
著者ElGamacy, M, Truffault, V, Zhu, H, Coles, M.
登録日2019-01-10
公開日2019-04-10
最終更新日2019-05-15
実験手法SOLUTION NMR
主引用文献Mapping Local Conformational Landscapes of Proteins in Solution.
Structure, 27, 2019
7SP3
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BU of 7sp3 by Molmil
E. coli RppH bound to Ap4A
分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CHLORIDE ION, FLUORIDE ION, ...
著者Serganov, A.A, Vasilyev, N, Nuthanakanti, A.
登録日2021-11-02
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A distinct RNA recognition mechanism governs Np 4 decapping by RppH.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QG3
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BU of 6qg3 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B)
分子名称: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
著者Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
登録日2019-01-10
公開日2019-06-26
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QGT
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BU of 6qgt by Molmil
The carbon monoxide inhibition of F420-reducing [NiFe] hydrogenase complex from Methanosarcina barkeri
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, Coenzyme F420 hydrogenase subunit beta, ...
著者Ilina, Y, Lorent, C, Katz, S, Jeoung, J.H, Shima, S, Horch, M, Zebger, I, Dobbek, H.
登録日2019-01-12
公開日2019-10-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.988 Å)
主引用文献X-ray Crystallography and Vibrational Spectroscopy Reveal the Key Determinants of Biocatalytic Dihydrogen Cycling by [NiFe] Hydrogenases.
Angew.Chem.Int.Ed.Engl., 58, 2019
7SV6
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BU of 7sv6 by Molmil
Crystal structure of SpaA-SLH/G46A/G109A in complex with 4,6-Pyr-beta-D-ManNAc-(1->4)-beta-D-GlcNAcOMe
分子名称: Surface (S-) layer glycoprotein, methyl 2-acetamido-4-O-{2-acetamido-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranoside
著者Legg, M.S.G, Evans, S.V.
登録日2021-11-18
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The S-layer homology domains of Paenibacillus alvei surface protein SpaA bind to cell wall polysaccharide through the terminal monosaccharide residue.
J.Biol.Chem., 298, 2022
7SMR
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BU of 7smr by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
登録日2021-10-26
公開日2022-03-09
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
6QHY
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BU of 6qhy by Molmil
Time resolved structural analysis of the full turnover of an enzyme - 100 ms
分子名称: Fluoroacetate dehalogenase, fluoroacetic acid
著者Schulz, E.C, Mehrabi, P, Pai, E.F, Miller, D.
登録日2019-01-17
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Time-resolved crystallography reveals allosteric communication aligned with molecular breathing.
Science, 365, 2019
6QI8
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BU of 6qi8 by Molmil
Truncated human R2TP complex, structure 3 (ADP-filled)
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
登録日2019-01-18
公開日2019-04-10
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
6QD9
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Leishmania major N-myristoyltransferase in complex with thienopyrimidine inhibitor IMP-0000065
分子名称: 3-[[2-[3-(dimethylamino)propyl-methyl-amino]thieno[3,2-d]pyrimidin-4-yl]-methyl-amino]propanenitrile, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ...
著者Brannigan, J.A.
登録日2019-01-01
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.
J.Med.Chem., 63, 2020
6QDH
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BU of 6qdh by Molmil
Leishmania major N-myristoyltransferase in complex with quinazoline inhibitor IMP-0000906
分子名称: 4-[ethyl(methyl)amino]-2-[methyl-(1-methylpiperidin-4-yl)amino]-~{N}-(1,3,5-trimethylpyrazol-4-yl)quinazoline-6-sulfonamide, Glycylpeptide N-tetradecanoyltransferase, MAGNESIUM ION, ...
著者Brannigan, J.A.
登録日2019-01-01
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Novel Thienopyrimidine Inhibitors of Leishmania N -Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.
J.Med.Chem., 63, 2020
6QJA
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Organizational principles of the NuMA-Dynein interaction interface and implications for mitotic spindle functions
分子名称: CHLORIDE ION, MAGNESIUM ION, Nuclear mitotic apparatus protein 1
著者Renna, C, Rizzelli, F, Carminati, M, Gaddoni, C, Pirovano, L, Cecatiello, V, Pasqualato, S, Mapelli, M.
登録日2019-01-23
公開日2020-02-05
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Organizational Principles of the NuMA-Dynein Interaction Interface and Implications for Mitotic Spindle Functions.
Structure, 28, 2020

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