2JXB
| Structure of CD3epsilon-Nck2 first SH3 domain complex | 分子名称: | T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2 | 著者 | Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G. | 登録日 | 2007-11-09 | 公開日 | 2008-09-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity. J.Mol.Biol., 380, 2008
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2N8G
| NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens | 分子名称: | Homeobox protein GBX-1 | 著者 | Proudfoot, A.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) | 登録日 | 2015-10-15 | 公開日 | 2015-10-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of the homeodomain transcription factor Gbx1[E23R,R58E] from Homo sapiens To be Published
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2K1W
| NMR solution structure of M-crystallin in calcium loaded form(holo). | 分子名称: | Beta/gama crystallin family protein, CALCIUM ION | 著者 | Barnwal, R, Jobby, M, Devi, K, Sharma, Y, Chary, K. | 登録日 | 2008-03-17 | 公開日 | 2009-01-27 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and calcium-binding properties of M-crystallin, a primordial betagamma-crystallin from archaea. J.Mol.Biol., 386, 2009
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2JDF
| Human gamma-B crystallin | 分子名称: | GAMMA CRYSTALLIN B | 著者 | Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U. | 登録日 | 2007-01-08 | 公開日 | 2007-07-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein. J.Mol.Biol., 372, 2007
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2JGW
| Structure of CCP module 7 of complement factor H - The AMD at risk varient (402H) | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | 登録日 | 2007-02-16 | 公開日 | 2007-03-20 | 最終更新日 | 2018-05-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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2JPA
| Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA | 分子名称: | DNA (5'-D(P*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DG)-3'), Wilms tumor 1, ... | 著者 | Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E. | 登録日 | 2007-05-01 | 公開日 | 2007-10-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA J.Mol.Biol., 372, 2007
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2PCL
| Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5 | 分子名称: | 1,2-ETHANEDIOL, Lipoprotein-releasing system ATP-binding protein lolD, MAGNESIUM ION, ... | 著者 | Jeyakanthan, J, Kanaujia, S.P, Rafi, Z.A, Sekar, K, Ebihara, A, Nakagawa, N, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of ABC transporter with complex (aq_297) from aquifex aeolicus VF5 To be Published
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2P2R
| Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 | 著者 | James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. | 登録日 | 2007-03-07 | 公開日 | 2007-06-12 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
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2JTE
| Third SH3 domain of CD2AP | 分子名称: | CD2-associated protein | 著者 | van Nuland, N.A.J, Ortega, R.J, Romero Romero, M, Ab, E, Ora, A, Lopez, M.O, Azuaga, A.I. | 登録日 | 2007-07-28 | 公開日 | 2007-12-11 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | The high resolution NMR structure of the third SH3 domain of CD2AP. J.Biomol.Nmr, 39, 2007
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2JUU
| allo-ThrA3 DKP-insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2007-09-03 | 公開日 | 2007-10-16 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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2P47
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: SE5B-TRI crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2P55
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2OZA
| Structure of p38alpha complex | 分子名称: | MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14 | 著者 | White, A, Pargellis, C.A, Studts, J.M, Werneburg, B.G, Farmer II, B.T. | 登録日 | 2007-02-25 | 公開日 | 2007-04-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis of MAPK-activated protein kinase 2:p38 assembly Proc.Natl.Acad.Sci.Usa, 104, 2007
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4MBI
| Discovery of Pyrazolo[1,5a]pyrimidine-based Pim1 Inhibitors | 分子名称: | N,N-dimethyl-N'-[3-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]ethane-1,2-diamine, Serine/threonine-protein kinase pim-1 | 著者 | Azevedo, R, Fischmann, T.O. | 登録日 | 2013-08-19 | 公開日 | 2013-09-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach. Bioorg.Med.Chem.Lett., 23, 2013
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2JJP
| Structure of cytochrome P450 EryK in complex with inhibitor ketoconazole (KC) | 分子名称: | 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B. | 登録日 | 2008-04-15 | 公開日 | 2009-07-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States. Biochemistry, 49, 2010
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2P85
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2P2L
| Rac1-GDP-Zinc Complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION | 著者 | Prehna, G, Stebbins, C.E. | 登録日 | 2007-03-07 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium. Acta Crystallogr.,Sect.D, 63, 2007
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2JMA
| R21A Spc-SH3:P41 complex | 分子名称: | P41 peptide, Spectrin alpha chain, brain | 著者 | van Nuland, N.A.J, Casares, S, Ab, E, Eshuis, H, Lopez-Mayorga, O, Conejero-Lara, F. | 登録日 | 2006-10-25 | 公開日 | 2007-04-24 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The high-resolution NMR structure of the R21A Spc-SH3:P41 complex: Understanding the determinants of binding affinity by comparison with Abl-SH3 Bmc Struct.Biol., 7, 2007
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2JS2
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2P8H
| Crystal structure of human beta secretase complexed with inhibitor | 分子名称: | Beta-secretase 1, N-{(1S,2S)-1-BENZYL-2-HYDROXY-2-[(4S)-1,2,2-TRIMETHYL-5-OXOIMIDAZOLIDIN-4-YL]ETHYL}-N'-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-5-[METHYL(METHYLSULFONYL)AMINO]ISOPHTHALAMIDE | 著者 | Munshi, S. | 登録日 | 2007-03-22 | 公開日 | 2007-08-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1. Chemmedchem, 2, 2007
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2P44
| Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE5A-mono-1 crystal form with five se-met sites (M34, M51, F68M, M83, L86M) in vhh scaffold | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2PEF
| Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | 分子名称: | Serine protease inhibitor | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | 登録日 | 2007-04-03 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
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2FC9
| Solution structure of the RRM_1 domain of NCL protein | 分子名称: | NCL protein | 著者 | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-12-12 | 公開日 | 2006-06-12 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the RRM_1 domain of NCL protein To be published
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2P4J
| Crystal structure of beta-secretase bond to an inhibitor with Isophthalamide Derivatives at P2-P3 | 分子名称: | Beta-secretase 1, N-[(1S,2S,4R)-2-HYDROXY-1-ISOBUTYL-5-({(1S)-1-[(ISOPROPYLAMINO)CARBONYL]-2-METHYLPROPYL}AMINO)-4-METHYL-5-OXOPENTYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE | 著者 | Hong, L, Ghosh, A.K, Tang, J. | 登録日 | 2007-03-12 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. J.Med.Chem., 50, 2007
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2FEB
| NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a) | 分子名称: | Apolipoprotein(a) | 著者 | Chitayat, S, Kanelis, V, Koschinsky, M.L, Smith, S.P. | 登録日 | 2005-12-15 | 公開日 | 2006-12-26 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance (NMR) solution structure, dynamics, and binding properties of the kringle IV type 8 module of apolipoprotein(a). Biochemistry, 46, 2007
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