PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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2GQI	Solution structure of the SH3 domain of human Ras GTPase-activating protein 1 分子名称: Ras GTPase-activating protein 1 著者 Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-21 公開日 2006-10-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the SH3 domain of human Ras GTPase-activating protein 1 To be Published
2GU8	Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies 分子名称: CAMP-dependent protein kinase, alpha-catalytic subunit, N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE, ... 著者 Murray, J.M. 登録日 2006-04-28 公開日 2007-05-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies Bioorg.Med.Chem.Lett., 16, 2006
2GRZ	5ns Photoproduct of the M37V mutant of Scapharca HbI 分子名称: CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Knapp, J.E, Pahl, R, Srajer, V, Royer Jr, W.E. 登録日 2006-04-25 公開日 2006-05-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Allosteric action in real time: Time-resolved crystallographic studies of a cooperative dimeric hemoglobin. Proc.Natl.Acad.Sci.Usa, 103, 2006
2GSB	Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 分子名称: Ras GTPase-activating protein 1 著者 Kurosaki, C, Suetake, T, Yoshida, M, Hayashi, F, Yokoyma, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-26 公開日 2007-05-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 To be Published
2OVA	X-ray structure of Human Complement Protein C8gamma Y83W Mutant 分子名称: Complement component 8, gamma polypeptide 著者 Chiswell, B, Lovelace, L.L, Brannen, C, Ortlund, E.A, Lebioda, L, Sodetz, J.M. 登録日 2007-02-13 公開日 2007-05-22 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural features of the ligand binding site on human complement protein C8gamma: A member of the lipocalin family Biochim.Biophys.Acta, 1774, 2007
2PE0	CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 5-Hydroxy-3-[1-(1H-pyrrol-2-yl)-eth-(Z)-ylidene]-1,3-dihydro-indol-2-one COMPLEX 分子名称: 3-phosphoinositide-dependent protein kinase 1, 5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE, GLYCEROL, ... 著者 Whitlow, M, Adler, M. 登録日 2007-04-01 公開日 2007-06-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: Design, synthesis and biological activity. Bioorg.Med.Chem.Lett., 17, 2007
2H4Q	Crystal structure of a M-loop deletion variant of MENT in the cleaved conformation 分子名称: Heterochromatin-associated protein MENT 著者 Whisstock, J.C, Buckle, A.M, McGowan, S, Irving, J.A. 登録日 2006-05-25 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
2OLK	ABC Protein ArtP in complex with ADP-beta-S 分子名称: 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, Amino acid ABC transporter 著者 Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. 登録日 2007-01-19 公開日 2008-01-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the ATP-binding cassette (ABC) protein ArtP from Geobacillus stearothermophilus reveal a stable dimer in the post hydrolysis state and an asymmetry in the dimerization region To be Published
2H5C	0.82A resolution crystal structure of alpha-lytic protease at pH 5 分子名称: ALPHA-LYTIC PROTEASE, GLYCEROL, SULFATE ION 著者 Fuhrmann, C.N, Daugherty, M.D, Agard, D.A. 登録日 2006-05-25 公開日 2006-09-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (0.82 Å) 主引用文献 Subangstrom crystallography reveals that short ionic hydrogen bonds, and not a His-Asp low-barrier hydrogen bond, stabilize the transition state in serine protease catalysis J.Am.Chem.Soc., 128, 2006
2ORL	Solution structure of the cytochrome c- para-aminophenol adduct 分子名称: 4-AMINOPHENOL, Cytochrome c iso-1, HEME C 著者 Assfalg, M, Bertini, I, Del Conte, R, Giachetti, A, Turano, P. 登録日 2007-02-03 公開日 2007-04-24 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Cytochrome c and organic molecules: solution structure of the p-aminophenol adduct. Biochemistry, 46, 2007
2OMI	Structure of human insulin cocrystallized with protamine 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Norrman, M, Schluckebier, G. 登録日 2007-01-22 公開日 2007-03-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structural characterization of insulin NPH formulations. EUR.J.PHARM.SCI., 30, 2007
2H5Z	Crystallographic structure of digestive lysozyme 1 from Musca domestica bound to chitotetraose at 1.92 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme 1 著者 Valerio, A.A, Cancado, F.C, Marana, S.R, Barbosa, J.A.R.G. 登録日 2006-05-29 公開日 2007-06-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystallization, data collection and phasing of two digestive lysozymes from Musca domestica Acta Crystallogr.,Sect.F, 62, 2006
2H72	Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin 著者 Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2006-06-01 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group To be Published
2H7R	L244A mutant of Cytochrome P450cam complexed with imidazole 分子名称: 1-METHYLIMIDAZOLE, Cytochrome P450-cam, PROTOPORPHYRIN IX CONTAINING FE 著者 Verras, A, Alian, A, Montellano, P.R. 登録日 2006-06-02 公開日 2006-10-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation. Protein Eng.Des.Sel., 19, 2006
2OP2	Crystal structure of RNase double-mutant V43C R85C with extra disulphide bond 分子名称: Ribonuclease pancreatic 著者 Kurinov, I. 登録日 2007-01-26 公開日 2007-10-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Implementation of a k/k(0) Method to Identify Long-Range Structure in Transition States during Conformational Folding/Unfolding of Proteins. Structure, 15, 2007
2H67	NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures 分子名称: Insulin A chain, Insulin B chain 著者 Hua, Q.X, Liu, M, Hu, S.Q, Jia, W, Arvan, P, Weiss, M.A. 登録日 2006-05-30 公開日 2006-07-18 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 A Conserved Histidine in Insulin Is Required for the Foldability of Human Proinsulin: Structure and function of an Alab5 analog. J.Biol.Chem., 281, 2006
2NOT	NOTECHIS II-5, NEUROTOXIC PHOSPHOLIPASE A2 FROM NOTECHIS SCUTATUS SCUTATUS 分子名称: PHOSPHOLIPASE A2 著者 Carredano, E, Westerlund, B, Persson, B, Saarinen, M, Ramaswamy, S, Eaker, D, Eklund, H. 登録日 1997-03-03 公開日 1997-06-16 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2. Toxicon, 36, 1998
2H74	Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin 著者 Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M. 登録日 2006-06-01 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Thioredoxin Mutant D2E in Hexagonal (p61) Space Group To be Published
2HB4	Structure of HIV Protease NL4-3 in an Unliganded State 分子名称: MAGNESIUM ION, Protease, R-1,2-PROPANEDIOL 著者 Heaslet, H, Tam, K, Elder, J.H, Stout, C.D. 登録日 2006-06-13 公開日 2007-06-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63, 2007
2IWR	Gtpase Like Domain Of Centaurin Gamma 1 (Human) 分子名称: CENTAURIN GAMMA 1 著者 Elkins, J.M, Soundararajan, M, Yang, X, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A, Structural Genomics Consortium (SGC) 登録日 2006-07-03 公開日 2006-07-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Centaurin Gamma-1 Gtpase-Like Domain Functions as an Ntpase. Biochem.J., 401, 2007
2N9I	Solution structure of reduced human cytochrome c 分子名称: Cytochrome c, HEME C 著者 Imai, M, Saio, T, Kumeta, H, Uchida, T, Inagaki, F, Ishimori, K. 登録日 2015-11-24 公開日 2016-02-17 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Investigation of the redox-dependent modulation of structure and dynamics in human cytochrome c Biochem.Biophys.Res.Commun., 469, 2016
2NBR	The Solution Structure of Human gammaC-crystallin 分子名称: Gamma-crystallin C 著者 Dixit, K, Pande, A, Pande, J, Sarma, S.P. 登録日 2016-03-12 公開日 2016-06-01 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Nuclear Magnetic Resonance Structure of a Major Lens Protein, Human gamma C-Crystallin: Role of the Dipole Moment in Protein Solubility. Biochemistry, 55, 2016
2NAM	Full-length WT SOD1 in DPC MICELLE 分子名称: Superoxide dismutase [Cu-Zn] 著者 Lim, L, Song, J. 登録日 2016-01-06 公開日 2016-12-14 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 SALS-linked WT-SOD1 adopts a highly similar helical conformation as FALS-causing L126Z-SOD1 in a membrane environment Biochim.Biophys.Acta, 1858, 2016
2J1M	P450 BM3 Heme domain in complex with DMSO 分子名称: CYTOCHROME P450 102, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Kuper, J, Tuck-Seng, W, Roccatano, D, Wilmanns, M, Schwaneberg, U. 登録日 2006-08-14 公開日 2007-05-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3. J.Am.Chem.Soc., 129, 2007
2NMY	Crystal structure analysis of HIV-1 protease mutant V82A with a inhibitor saquinavir 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, PROTEASE, ... 著者 Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T. 登録日 2006-10-23 公開日 2007-03-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir. Proteins, 67, 2007

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