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4ERC
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Structure of VHZ bound to metavanadate
分子名称: Dual specificity protein phosphatase 23, oxido(dioxo)vanadium
著者Vyacheslav, K, Alvan, C.H, Sean, J.J.
登録日2012-04-19
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献New Aspects of the Phosphatase VHZ Revealed by a High-Resolution Structure with Vanadate and Substrate Screening.
Biochemistry, 51, 2012
6TZ6
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Crystal Structure of Candida Albicans Calcineurin A, Calcineurin B, FKBP12 and FK506 (Tacrolimus)
分子名称: 1,2-ETHANEDIOL, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ...
著者Fox III, D, Lukacs, C.M.
登録日2019-08-10
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
5Y16
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Crystal structure of human DUSP28(Y102H)
分子名称: CHLORIDE ION, Dual specificity phosphatase 28, PHOSPHATE ION
著者Ku, B, Kim, M, Kim, S.J, Ryu, S.E.
登録日2017-07-19
公開日2017-11-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
PLoS ONE, 12, 2017
4FC8
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Crystal structure of transcription regulator protein Rtr1 from Kluyveromyces lactis
分子名称: ZINC ION, transcription protein Rtr1
著者Xiang, K, Tong, L.
登録日2012-05-24
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity.
Nat Commun, 3, 2012
1FPZ
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CRYSTAL STRUCTURE ANALYSIS OF KINASE ASSOCIATED PHOSPHATASE (KAP) WITH A SUBSTITUTION OF THE CATALYTIC SITE CYSTEINE (CYS140) TO A SERINE
分子名称: CYCLIN-DEPENDENT KINASE INHIBITOR 3, SULFATE ION
著者Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D.
登録日2000-09-01
公開日2001-05-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
Mol.Cell, 7, 2001
4G9J
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Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide
著者Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J.
登録日2012-07-24
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells.
Angew.Chem.Int.Ed.Engl., 51, 2012
1HD3
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A-SPECTRIN SH3 DOMAIN F52Y MUTANT
分子名称: GLYCEROL, SPECTRIN ALPHA CHAIN, SULFATE ION
著者Vega, M.C, Viguera, A.R, Serrano, L.
登録日2000-11-06
公開日2001-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Unspecific Hydrophobic Stabilization of Folding Transition States
Proc.Natl.Acad.Sci.USA, 99, 2002
5ZQV
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Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GM
分子名称: CITRATE ANION, MANGANESE (II) ION, Protein phosphatase 1 regulatory subunit 3A, ...
著者Yu, J, Xiang, S.
登録日2018-04-20
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis for protein phosphatase 1 recruitment by glycogen-targeting subunits.
FEBS J., 285, 2018
6W1N
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Pig Ryanodine Receptor (WT) in 5mM EGTA condition
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-03-04
公開日2021-01-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
1IT6
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CALYCULIN A AND THE CATALYTIC SUBUNIT OF PROTEIN PHOSPHATASE 1
分子名称: CALYCULIN A, MANGANESE (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE 1 GAMMA (PP1-GAMMA) CATALYTIC SUBUNIT
著者Kita, A, Matsunaga, S, Takai, A, Kataiwa, H, Wakimoto, T, Fusetani, N, Isobe, M, Miki, K.
登録日2002-01-09
公開日2002-05-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the complex between calyculin A and the catalytic subunit of protein phosphatase 1.
Structure, 10, 2002
1FJM
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Protein serine/threonine phosphatase-1 (alpha isoform, type 1) complexed with microcystin-LR toxin
分子名称: BETA-MERCAPTOETHANOL, MANGANESE (II) ION, PROTEIN SERINE/THREONINE PHOSPHATASE-1 (ALPHA ISOFORM, ...
著者Goldberg, J, Nairn, A.C, Kuriyan, J.
登録日1995-12-17
公開日1996-06-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1.
Nature, 376, 1995
4H3H
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Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7
分子名称: PHOSPHATE ION, Pol II CTD peptide, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
著者Xiang, K, Tong, L.
登録日2012-09-13
公開日2012-10-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
1J4X
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HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX
分子名称: DDE(AHP)(TPO)G(PTR)VATR, DUAL SPECIFICITY PROTEIN PHOSPHATASE 3
著者Schumacher, M.A, Todd, J.L, Tanner, K.G, Denu, J.M.
登録日2001-12-13
公開日2001-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002
1G5B
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BACTERIOPHAGE LAMBDA SER/THR PROTEIN PHOSPHATASE
分子名称: MANGANESE (II) ION, MERCURY (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE, ...
著者Voegtli, W.C, White, D.J, Reiter, N.J, Rusnak, F, Rosenzweig, A.C.
登録日2000-10-31
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the bacteriophage lambda Ser/Thr protein phosphatase with sulfate ion bound in two coordination modes.
Biochemistry, 39, 2000
1JK7
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CRYSTAL STRUCTURE OF THE TUMOR-PROMOTER OKADAIC ACID BOUND TO PROTEIN PHOSPHATASE-1
分子名称: BETA-MERCAPTOETHANOL, MANGANESE (II) ION, OKADAIC ACID, ...
著者Maynes, J.T, Bateman, K.S, Cherney, M.M, Das, A.K, James, M.N.
登録日2001-07-11
公開日2001-08-15
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1.
J.Biol.Chem., 276, 2001
4H3K
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Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA polymerase II CTD peptide phosphorylated at Ser-2, Ser-5 and Ser-7
分子名称: Hexapeptide, PHOSPHATE ION, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, ...
著者Xiang, K, Tong, L.
登録日2012-09-13
公開日2012-10-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.
Genes Dev., 26, 2012
2Y96
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Structure of human dual-specificity phosphatase 27
分子名称: DUAL SPECIFICITY PHOSPHATASE DUPD1, SULFATE ION
著者Lountos, G.T, Tropea, J.E, Waugh, D.S.
登録日2011-02-11
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure of Human Dual-Specificity Phosphatase at 2.38A Resolution
Acta Crystallogr.,Sect.D, 67, 2011
2WGP
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BU of 2wgp by Molmil
Crystal structure of human dual specificity phosphatase 14
分子名称: DUAL SPECIFICITY PROTEIN PHOSPHATASE 14, PHOSPHATE ION
著者Lountos, G.T, Tropea, J.E, Cherry, S, Waugh, D.S.
登録日2009-04-22
公開日2009-10-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Overproduction, Purification and Structure Determination of Human Dual-Specificity Phosphatase 14.
Acta Crystallogr.,Sect.D, 65, 2009
2VRF
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CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN
分子名称: 1,2-ETHANEDIOL, BETA-2-SYNTROPHIN
著者Sun, Z, Roos, A.K, Pike, A.C.W, Pilka, E.S, Cooper, C, Elkins, J.M, Murray, J, Arrowsmith, C.H, Doyle, D, Edwards, A, von Delft, F, Bountra, C, Oppermann, U.
登録日2008-03-31
公開日2008-04-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Human Beta-2-Syntrophin Pdz Domain
To be Published
1DTL
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CRYSTAL STRUCTURE OF CALCIUM-SATURATED (3CA2+) CARDIAC TROPONIN C COMPLEXED WITH THE CALCIUM SENSITIZER BEPRIDIL AT 2.15 A RESOLUTION
分子名称: 1-ISOBUTOXY-2-PYRROLIDINO-3[N-BENZYLANILINO] PROPANE, CALCIUM ION, CARDIAC TROPONIN C
著者Li, Y, Love, M.L, Putkey, J.A, Cohen, C.
登録日2000-01-12
公開日2000-05-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Bepridil opens the regulatory N-terminal lobe of cardiac troponin C.
Proc.Natl.Acad.Sci.USA, 97, 2000
1E6G
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A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
分子名称: SPECTRIN ALPHA CHAIN, SULFATE ION
著者Vega, M.C, Serrano, L.
登録日2000-08-15
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
2WWM
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Crystal structure of the Titin M10-Obscurin like 1 Ig complex in space group P1
分子名称: OBSCURIN-LIKE PROTEIN 1, TITIN
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2009-10-26
公開日2010-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insight Into M-Band Assembly and Mechanics from the Titin-Obscurin-Like-1 Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
1E6H
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A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
分子名称: SPECTRIN ALPHA CHAIN
著者Vega, M.C, Serrano, L.
登録日2000-08-17
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1FQ1
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CRYSTAL STRUCTURE OF KINASE ASSOCIATED PHOSPHATASE (KAP) IN COMPLEX WITH PHOSPHO-CDK2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CELL DIVISION PROTEIN KINASE 2, CYCLIN-DEPENDENT KINASE INHIBITOR 3, ...
著者Song, H, Hanlon, N, Brown, N.R, Noble, M.E.M, Johnson, L.N, Barford, D.
登録日2000-09-01
公開日2001-05-09
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
Mol.Cell, 7, 2001
2WP3
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Crystal structure of the Titin M10-Obscurin like 1 Ig complex
分子名称: GLYCEROL, OBSCURIN-LIKE PROTEIN 1, SULFATE ION, ...
著者Pernigo, S, Fuzukawa, A, Gautel, M, Steiner, R.A.
登録日2009-08-02
公開日2010-02-16
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural Insight Into M-Band Assembly and Mechanics from the Titin-Obscurin-Like-1 Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010

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