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1T8M
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CRYSTAL STRUCTURE OF THE P1 HIS BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
分子名称: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
著者Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
登録日2004-05-13
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T7C
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CRYSTAL STRUCTURE OF THE P1 GLU BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
分子名称: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
著者Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
登録日2004-05-09
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1T8O
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CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
分子名称: Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION
著者Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O.
登録日2004-05-13
公開日2005-03-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
J.Mol.Biol., 344, 2004
1XG6
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The crystal structure of the P1 mutant (Leu to Arg)of a Winged bean chymotrypsin inhibitor(Kunitz)solved at 2.15A resolution
分子名称: Chymotrypsin inhibitor 3
著者Sen, U, Dattagupta, J.K, Dasgupta, J, Khamrui, S.
登録日2004-09-16
公開日2005-08-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Single mutation at P1 of a chymotrypsin inhibitor changes it to a trypsin inhibitor: X-ray structural (2.15 A) and biochemical basis
Biochim.Biophys.Acta, 1752, 2005
1MCT
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THE REFINED 1.6 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PORCINE BETA-TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY
分子名称: BETA-TRYPSIN, CALCIUM ION, TRYPSIN INHIBITOR A
著者Huang, Q, Liu, S, Tang, Y.
登録日1992-10-24
公開日1994-01-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Refined 1.6 A resolution crystal structure of the complex formed between porcine beta-trypsin and MCTI-A, a trypsin inhibitor of the squash family. Detailed comparison with bovine beta-trypsin and its complex.
J.Mol.Biol., 229, 1993
4AN6
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Kuntiz type trypsin inhibitor with factor Xa inhibitory activity
分子名称: TRYPSIN INHIBITOR
著者Patil, D.N, Kumar, P.
登録日2012-03-15
公開日2012-11-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural Basis for Dual Inhibitory Role of Tamarind Kunitz Inhibitor (Tki) Against Factor Xa and Trypsin.
FEBS J., 279, 2012
1P2N
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Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
分子名称: Chymotrypsinogen A, Pancreatic trypsin inhibitor, SULFATE ION
著者Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O.
登録日2003-04-15
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
1P2M
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Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
分子名称: Chymotrypsinogen A, Pancreatic trypsin inhibitor, SULFATE ION
著者Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O.
登録日2003-04-15
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
1P2O
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Structural consequences of accommodation of four non-cognate amino-acid residues in the S1 pocket of bovine trypsin and chymotrypsin
分子名称: Chymotrypsinogen A, Pancreatic trypsin inhibitor, SULFATE ION
著者Helland, R, Czapinska, H, Leiros, I, Olufsen, M, Otlewski, J, Smalaas, A.O.
登録日2003-04-15
公開日2004-04-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
J.Mol.Biol., 333, 2003
4H4F
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Crystal structure of human chymotrypsin C (CTRC) bound to inhibitor eglin c from Hirudo medicinalis
分子名称: Chymotrypsin-C, Eglin C, PHOSPHATE ION
著者Batra, J, Soares, A.S, Radisky, E.S.
登録日2012-09-17
公開日2013-02-27
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Long-range Electrostatic Complementarity Governs Substrate Recognition by Human Chymotrypsin C, a Key Regulator of Digestive Enzyme Activation.
J.Biol.Chem., 288, 2013
1UTM
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Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements
分子名称: 2-PHENYLETHYLAMINE, CALCIUM ION, TRYPSIN I
著者Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O.
登録日2003-12-09
公開日2004-01-09
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
1GL1
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structure of the complex between bovine alpha-chymotrypsin and PMP-C, an inhibitor from the insect Locusta migratoria
分子名称: ALPHA-CHYMOTRYPSIN, CADMIUM ION, PROTEASE INHIBITOR LCMI II
著者Roussel, A, Kellenberger, C.
登録日2001-08-22
公開日2001-11-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity
J.Biol.Chem., 276, 2001
2AH4
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guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution
分子名称: 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ...
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006
1UTK
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Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements
分子名称: CALCIUM ION, SULFATE ION, TRYPSIN I
著者Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O.
登録日2003-12-09
公開日2004-01-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
2A31
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Trypsin in complex with borate
分子名称: BORATE ION, CALCIUM ION, GUANIDINE-3-PROPANOL, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
2CGA
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BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION
分子名称: CHYMOTRYPSINOGEN A
著者Wang, D, Bode, W, Huber, R.
登録日1987-01-16
公開日1987-04-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
J.Mol.Biol., 185, 1985
1UTL
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Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-PHENYLPROPYLAMINE, CALCIUM ION, ...
著者Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O.
登録日2003-12-09
公開日2004-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
1YYY
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Trypsin inhibitors with rigid tripeptidyl aldehydes
分子名称: 2-{(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}-N-{(2S)-1-[(3S)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl}acetamide, CALCIUM ION, TRYPSIN
著者Krishnan, R, Zhang, E, Hakansson, K, Arni, R.K, Tulinsky, A, Lim-Wilby, M.S.L, Levy, O.E, Semple, J.E, Brunck, T.K.
登録日1998-06-03
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
Biochemistry, 37, 1998
3GCT
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STRUCTURE OF GAMMA-*CHYMOTRYPSIN IN THE RANGE $P*H 2.0 TO $P*H 10.5 SUGGESTS THAT GAMMA-CHYMOTRYPSIN IS A COVALENT ACYL-ENZYME ADDUCT AT LOW $P*H
分子名称: GAMMA-CHYMOTRYPSIN A, SULFATE ION, UNK PRO GLY ALA TYR PEPTIDE
著者Dixon, M.M, Matthews, B.W.
登録日1990-09-04
公開日1991-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH.
Int.J.Biol.Macromol., 13, 1991
1ZZZ
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BU of 1zzz by Molmil
Trypsin inhibitors with rigid tripeptidyl aldehydes
分子名称: 2-{(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}-N-{(2S)-1-[(3R)-1-carbamimidoylpiperidin-3-yl]-3-oxopropan-2-yl}acetamide, CALCIUM ION, TRYPSIN
著者Krishnan, R, Zhang, E, Hakansson, K, Arni, R.K, Tulinsky, A, Lim-Wilby, M.S.L, Levy, O.E, Semple, J.E, Brunck, T.K.
登録日1998-06-02
公開日1999-06-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes.
Biochemistry, 37, 1998
1UTJ
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Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements
分子名称: BENZYLAMINE, CALCIUM ION, TRYPSIN I
著者Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O.
登録日2003-12-09
公開日2004-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements
Protein Sci., 13, 2004
1AB9
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CRYSTAL STRUCTURE OF BOVINE GAMMA-CHYMOTRYPSIN
分子名称: GAMMA-CHYMOTRYPSIN, PENTAPEPTIDE (TPGVY), SULFATE ION
著者Sugio, S, Kashima, A, Inoue, Y, Maeda, I, Nose, T, Shimohigashi, Y.
登録日1997-02-05
公開日1997-08-20
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction.
Eur.J.Biochem., 255, 1998
1YKT
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Trypsin/Bpti complex mutant
分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Brown, C.K, Ohlendorf, D.H.
登録日2005-01-18
公開日2006-04-25
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin
J.Mol.Biol., 375, 2008
2A32
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Trypsin in complex with benzene boronic acid
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, BORATE ION, CALCIUM ION, ...
著者Transue, T.R, Gabel, S.A, London, R.E.
登録日2005-06-23
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献NMR and crystallographic characterization of adventitious borate binding by trypsin.
Bioconjug.Chem., 17, 2006
2AGG
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succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution
分子名称: CALCIUM ION, Cationic trypsin, SULFATE ION, ...
著者Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E.
登録日2005-07-26
公開日2006-05-16
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates
Proc.Natl.Acad.Sci.USA, 103, 2006

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