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8CZ0
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CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case VII
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ2
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BU of 8cz2 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class A type I with extended core from DLB case VII
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CZ3
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BU of 8cz3 by Molmil
CryoEM structure of amplified alpha-synuclein fibril class B type I with extended core from DLB case X
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
8CYT
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BU of 8cyt by Molmil
CryoEM structures of amplified alpha-synuclein fibril class A type I with extended core from DLB case I
分子名称: Alpha-synuclein
著者Zhou, Y, Sokratian, A, Xu, E, Viverette, E, Dillard, L, Yuan, Y, Li, J.Y, Matarangas, A, Bouvette, J, Borgnia, M, Bartesaghi, A, West, A.
登録日2022-05-24
公開日2023-05-31
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional landscape of alpha-synuclein fibril assemblies amplified from cerebrospinal fluid
To Be Published
7XJX
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BU of 7xjx by Molmil
The cryo-EM structure of Fe3+ induced alpha-syn fibril.
分子名称: Alpha-synuclein
著者Zhao, Q.Y, Tao, Y.Q, Zhao, K, Tao, Y.Q, Li, D.
登録日2022-04-18
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural Insights of Fe3+ Induced alpha-synuclein Fibrillation in Parkinson' Disease
J.Mol.Biol., 435, 2023
7WMM
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BU of 7wmm by Molmil
alpha-synuclein fibril-F0502B complex
分子名称: 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-01-15
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献alpha-synuclein fibril-F0502B complex
To Be Published
7WO0
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BU of 7wo0 by Molmil
CryoEM structure of human alpha-synuclein A53T fibril induced by calcium ions
分子名称: Alpha-synuclein
著者Wu, K.-P, Huang, J.Y.-C.
登録日2022-01-20
公開日2023-01-25
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation
To Be Published
7WNZ
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BU of 7wnz by Molmil
CryoEM structure of human alpha-synuclein A53T fibril
分子名称: Alpha-synuclein
著者Wu, K.-P, Huang, J.Y.-C.
登録日2022-01-20
公開日2023-01-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Calcium abolishes intramolecular long-range contacts and promotes hereditary alpha-synuclein A53T aggregation
To Be Published
7V4D
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BU of 7v4d by Molmil
Heparin-remodelled alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D.
登録日2021-08-12
公開日2022-08-17
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Heparin-remodelled alpha-synuclein fibrils
To Be Published
7UAK
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BU of 7uak by Molmil
Structure of recombinantly assembled A53E alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Zhou, K, Zhou, H.
登録日2022-03-13
公開日2023-03-29
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Cryo-EM structure of amyloid fibril formed by alpha-synuclein hereditary A53E mutation reveals a distinct protofilament interface.
J.Biol.Chem., 299, 2023
7YK2
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BU of 7yk2 by Molmil
Cryo-EM structure of Apo-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-21
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7YK8
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BU of 7yk8 by Molmil
Cryo-EM structure of dLAG3-alpha-syn fibril
分子名称: Alpha-synuclein
著者Xu, Q.H, Xia, W.C, Tao, Y.Q, Liu, C.
登録日2022-07-22
公開日2023-03-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Conformational Dynamics of an alpha-Synuclein Fibril upon Receptor Binding Revealed by Insensitive Nuclei Enhanced by Polarization Transfer-Based Solid-State Nuclear Magnetic Resonance and Cryo-Electron Microscopy.
J.Am.Chem.Soc., 145, 2023
7XO2
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BU of 7xo2 by Molmil
Minor polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO3
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BU of 7xo3 by Molmil
Type 1C alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-4) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO0
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BU of 7xo0 by Molmil
Minor polymorph inalpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7XO1
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BU of 7xo1 by Molmil
Major polymorph in alpha-synuclein fibril seeded by cerebrospinal fluid from a mid-to-late stage (mid-PD-1) Parkinson's disease patient
分子名称: Alpha-synuclein
著者Fan, Y, Sun, Y.P, Wang, J, Liu, C.
登録日2022-04-30
公開日2022-11-30
最終更新日2023-01-25
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational change of alpha-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
Structure, 31, 2023
7YNP
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BU of 7ynp by Molmil
BF227-bound alpha-synuclein fibrils
分子名称: 5-[(~{E})-2-(6-methoxy-1,3-benzoxazol-2-yl)ethenyl]-~{N},~{N}-dimethyl-1,3-thiazol-2-amine, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献BF227-bound alpha-synuclein fibrils
To Be Published
7YNR
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BU of 7ynr by Molmil
C05-03-bound alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献C05-03-bound alpha-synuclein fibrils
To Be Published
7YNN
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BU of 7ynn by Molmil
ThT-bound alpha-synuclein fibrils conformation 2
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献ThT-bound alpha-synuclein fibrils conformation 2
To Be Published
7YNL
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BU of 7ynl by Molmil
EB-bound alpha-synuclein fibrils
分子名称: 4-azanyl-6-[[4-[4-[(~{E})-(8-azanyl-1-oxidanyl-5,7-disulfo-naphthalen-2-yl)diazenyl]-3-methyl-phenyl]-2-methyl-phenyl]diazenyl]-5-oxidanyl-naphthalene-1,3-disulfonic acid, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献EB-bound alpha-synuclein fibrils
To Be Published
7YNO
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BU of 7yno by Molmil
PiB-bound alpha-synuclein fibrils conformation 1
分子名称: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献PiB-bound alpha-synuclein fibrils conformation 1
To Be Published
7YNM
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BU of 7ynm by Molmil
ThT-bound alpha-synuclein fibrils conformation 1
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献ThT-bound alpha-synuclein fibrils conformation 1
To Be Published
7YNF
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BU of 7ynf by Molmil
CCA-bound alpha-synuclein fibrils
分子名称: Alpha-synuclein, copper;trisodium;18-(2-carboxylatoethyl)-20-(carboxylatomethyl)-12-ethenyl-7-ethyl-3,8,13,17-tetramethyl-17,18-dihydroporphyrin-21,23-diide-2-carboxylate
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-30
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献CCA-bound alpha-synuclein fibrils
To Be Published
8A4L
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BU of 8a4l by Molmil
Lipidic alpha-synuclein fibril - polymorph L2A
分子名称: Alpha-synuclein
著者Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F.
登録日2022-06-12
公開日2022-08-17
最終更新日2022-11-23
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献The 3D structure of lipidic fibrils of alpha-synuclein.
Nat Commun, 13, 2022
8A9L
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BU of 8a9l by Molmil
Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies
分子名称: Alpha-synuclein, Unknown fragment
著者Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M.
登録日2022-06-28
公開日2022-08-31
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (2.16 Å)
主引用文献Structures of alpha-synuclein filaments from human brains with Lewy pathology.
Nature, 610, 2022

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件を2024-06-12に公開中

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