5TOW
| Crystal structure of the inactive form of S-adenosyl-L-homocysteine hydrolase from Thermotoga maritima in ternary complex with NADH and Adenosine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADENOSINE, ... | 著者 | Czyrko, J, Brzezinski, K. | 登録日 | 2016-10-19 | 公開日 | 2017-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | S-adenosyl-L-homocysteine hydrolase from a hyperthermophile (Thermotoga maritima) is expressed in Escherichia coli in inactive form - Biochemical and structural studies. Int. J. Biol. Macromol., 104, 2017
|
|
5UTU
| 2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE, Adenosylhomocysteinase, ... | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Stam, J, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-15 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | 2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD To Be Published
|
|
5V96
| |
5W49
| The crystal structure of human S-adenosylhomocysteine hydrolase (AHCY) bound to oxadiazole inhibitor | 分子名称: | (4-amino-1,2,5-oxadiazol-3-yl)[(3R)-3-{4-[(3-methoxyphenyl)amino]-6-methylpyridin-2-yl}pyrrolidin-1-yl]methanone, 1,2-ETHANEDIOL, Adenosylhomocysteinase, ... | 著者 | Dougan, D.R, Lawson, J.D, Lane, W. | 登録日 | 2017-06-09 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of AHCY inhibitors using novel high-throughput mass spectrometry. Biochem. Biophys. Res. Commun., 491, 2017
|
|
5TOV
| |
5W4B
| The crystal structure of human S-adenosylhomocysteine hydrolase (AHCY) bound to benzothiazole inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-[(2,5-dioxo-2,5-dihydro-1H-imidazol-1-yl)methyl]-N-[2-(morpholin-4-yl)-1,3-benzothiazol-6-yl]benzamide, Adenosylhomocysteinase, ... | 著者 | Dougan, D.R, Lawson, J.D, Lane, W. | 登録日 | 2017-06-09 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Identification of AHCY inhibitors using novel high-throughput mass spectrometry. Biochem. Biophys. Res. Commun., 491, 2017
|
|
8CFG
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment C04 | 分子名称: | 2-hydrazinyl-4-methoxypyrimidine, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry C04 To be published
|
|
8CFX
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H06 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H06 To be published
|
|
8CFJ
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment D10 | 分子名称: | 2-methyl-N-(4-methylphenyl)-L-alanine, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry D10 To be published
|
|
8CFH
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment C08 | 分子名称: | (3S)-3-hydroxy-2-methyl-2,3-dihydro-1H-isoindol-1-one, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry C08 To be published
|
|
8CG0
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H11 | 分子名称: | 1-cyclopentyl-3-[[(2~{S})-oxolan-2-yl]methyl]urea, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H11 To be published
|
|
8CFO
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment F04 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry F04 To be published
|
|
8CFI
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment D07 | 分子名称: | 2-fluoranyl-~{N}-(furan-2-ylmethyl)benzenesulfonamide, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry D07 To be published
|
|
8CFY
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H08 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H08 To be published
|
|
8CFM
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment E08 | 分子名称: | 5-(2-methoxyethyl)-1,3,4-oxadiazol-2-amine, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry E08 To be published
|
|
8CG1
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H12 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H12 To be published
|
|
8CFD
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment A07 | 分子名称: | (2-aminopyridin-3-yl)methanol, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry A07 To be published
|
|
8CFU
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment H02 | 分子名称: | 3-cyclopentyl-1-(piperazin-1-yl)propan-1-one, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry H02 To be published
|
|
8CFP
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment F09 | 分子名称: | 4-pyridin-2-ylphenol, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry F09 To be published
|
|
8CFK
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment E06 | 分子名称: | (3-endo)-8-benzyl-8-azabicyclo[3.2.1]octan-3-ol, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry E06 To be published
|
|
8CFB
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment D02 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment D02 To be published
|
|
8CFT
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment G12 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry G12 To be published
|
|
8CFL
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment E07 | 分子名称: | 1-(1-methyl-1,2,3,4-tetrahydroquinolin-6-yl)methanamine, ADENINE, Adenosylhomocysteinase, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry E07 To be published
|
|
8CG2
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment B07 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry B07 To be published
|
|
8CFN
| Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with F2X-Entry library fragment F03 | 分子名称: | ADENINE, Adenosylhomocysteinase, DIMETHYL SULFOXIDE, ... | 著者 | Malecki, P.H, Gawel, M, Stepniewska, M, Brzezinski, K. | 登録日 | 2023-02-03 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Crystal structure of S-adenosyl-L-homocysteine hydrolase from P. aeruginosa in complex with fragment F2X-Entry F03 To be published
|
|