PDB: 522 件ウェブページステータス検索Chemie searchBIRD

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5QU3	Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QUA	Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A 分子名称: Cytoplasmic protein NCK1, SULFATE ION 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 分子名称: Cytoplasmic protein NCK1 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY 分子名称: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU7	Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU4	Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
4OMO	Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OML	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMN	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMQ	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant S94A 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
4OMP	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K 分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2014-12-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9, 2014
4OMM	Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-01-27 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation To be Published
5UL6	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions 分子名称: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus 著者 Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. 登録日 2017-01-24 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chem. Biol., 12, 2017
4QT7	Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein 分子名称: NS5A, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Bacarizo, J. 登録日 2014-07-07 公開日 2014-12-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus. J.Struct.Biol., 189, 2015
5VEI	Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 分子名称: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2017-04-04 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2 To be Published
7PVZ	Crystal structure of the intertwined dimer of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant 分子名称: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-11-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PW2	Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E mutant 分子名称: Non-specific protein-tyrosine kinase 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVT	Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Tyrosine-protein kinase transforming protein Src, ... 著者 Camara-Artigas, A, Salinas-Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the v-Src SH3 domain Q128R mutant in complex with the synthetic peptide VSL12 To be published
7PW0	Crystal structure of the c-Src SH3 domain N112G-N113Y-T114N-E115H mutant 分子名称: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVS	Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E-G92N-Y93N-N94T-H95E mutant in presence of PEG 200 分子名称: DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, SODIUM ION, ... 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVY	Crystal structure of the c-Src SH3 domain E93V-S94A-R95S-T96G mutant 分子名称: Isoform 2 of Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVV	Crystal structure of the Abl SH3 domain G92N-Y93N-N94T-H95E mutant 分子名称: Bcr-abl1 e6a2 chimeric protein, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVQ	Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E-G92N-Y93N-N94T-H95E mutant in the space group P21221 分子名称: Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published
7PVX	Crystal structure of the c-Src SH3 domain mutant E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H in complex with the synthetic peptide VSL12 分子名称: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, VSL12 peptide 著者 Camara-Artigas, A, Salinas Garcia, M.C. 登録日 2021-10-05 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystal structure of the c-Src SH3 domain mutants of the specificity region in complex with polyproline peptides To be published

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