4MBU
 
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6J3P
 | | Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n | | 分子名称: | 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A | | 著者 | Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y. | | 登録日 | 2019-01-05 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.598 Å) | | 主引用文献 | Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
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5TRM
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5TRL
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8HEH
 | | Crystal structure of GCN5-related N-acetyltransferase 05790 | | 分子名称: | COENZYME A, GLYCEROL, GNAT family N-acetyltransferase | | 著者 | Xu, M.X, Ran, T.T, Wang, W. | | 登録日 | 2022-11-08 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
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1B87
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1N71
 | | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A | | 分子名称: | COENZYME A, SULFATE ION, aac(6')-Ii | | 著者 | Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M. | | 登録日 | 2002-11-12 | | 公開日 | 2003-03-18 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
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3KJL
 | | Sgf11:Sus1 complex | | 分子名称: | Protein SUS1, SAGA-associated factor 11 | | 著者 | Stewart, M, Ellisdon, A.M. | | 登録日 | 2009-11-03 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
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3KIK
 | | Sgf11:Sus1 complex | | 分子名称: | Protein SUS1, SAGA-associated factor 11 | | 著者 | Stewart, M, Ellisdon, A.M. | | 登録日 | 2009-11-02 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
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7N1L
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6GTS
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4LDF
 | | Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190 | | 分子名称: | GCN5 like acetylase + bromodomain, GLYCEROL, UNKNOWN ATOM OR ION | | 著者 | Wernimont, A.K, Loppnau, P, Fonseca, M, Knapp, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Mottaghi, K, Structural Genomics Consortium (SGC) | | 登録日 | 2013-06-24 | | 公開日 | 2013-07-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
TO BE PUBLISHED
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3D7C
 | | Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2 | | 分子名称: | General control of amino acid synthesis protein 5-like 2 | | 著者 | Filippakopoulos, P, Eswaran, J, Picaud, S, Fedorov, O, Murray, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-05-21 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2VZY
 | | Crystal structure of Rv0802c from Mycobacterium tuberculosis in an unliganded form. | | 分子名称: | 2-ETHOXYETHANOL, ACETATE ION, CITRATE ANION, ... | | 著者 | Vetting, M.W, Errey, J.C, Blanchard, J.S. | | 登録日 | 2008-08-07 | | 公開日 | 2009-04-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
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2VZZ
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6YCA
 | | Crystal structure of Eis1 from Mycobacterium abscessus | | 分子名称: | ACETYL COENZYME *A, SULFATE ION, Uncharacterized N-acetyltransferase D2E76_00625 | | 著者 | Blaise, M, Ung, K.L. | | 登録日 | 2020-03-18 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural analysis of the N-acetyltransferase Eis1 from Mycobacterium abscessus reveals the molecular determinants of its incapacity to modify aminoglycosides.
Proteins, 89, 2021
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8H66
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8H6D
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8H6C
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8H65
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5JPH
 | | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus in complex with CoA | | 分子名称: | Acetyltransferase SACOL1063, CHLORIDE ION, COENZYME A | | 著者 | Majorek, K.A, Osinski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-05-03 | | 公開日 | 2016-06-29 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
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5JQ4
 | | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus | | 分子名称: | 1,2-ETHANEDIOL, Acetyltransferase SACOL1063, CHLORIDE ION, ... | | 著者 | Majorek, K.A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2016-05-04 | | 公開日 | 2016-06-29 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
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7AK8
 | | Structure of Salmonella TacT1 toxin bound to TacA1 antitoxin C-terminal peptide | | 分子名称: | ACETYL COENZYME *A, GCN5 family acetyltransferase, GLYCEROL, ... | | 著者 | Grabe, G.J, Morgan, R.M.L, Helaine, S, Hare, S.A. | | 登録日 | 2020-09-30 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing.
Nat.Chem.Biol., 17, 2021
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3GY9
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3GYA
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