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4KLW
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 2-(aminocarbonyl)benzoate
分子名称: 1,2-ETHANEDIOL, 2-carbamoylbenzoic acid, SULFATE ION, ...
著者Majorek, K.A, Porebski, P.J, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-07
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
4KOU
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefixime
分子名称: (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 1,2-ETHANEDIOL, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Otwinowski, Z, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-12
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural, Functional, and Inhibition Studies of a Gcn5-related N-Acetyltransferase (GNAT) Superfamily Protein PA4794: A NEW C-TERMINAL LYSINE PROTEIN ACETYLTRANSFERASE FROM PSEUDOMONAS AERUGINOSA.
J.Biol.Chem., 288, 2013
4KUA
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BU of 4kua by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794
分子名称: 1,2-ETHANEDIOL, GNAT superfamily acetyltransferase PA4794, SULFATE ION
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-21
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4L8A
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BU of 4l8a by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine, ...
著者Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-06-16
公開日2013-07-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4L89
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Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with covalently bound CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, SULFATE ION, ...
著者Majorek, K.A, Chruszcz, M, Maclean, E, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-06-16
公開日2013-07-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
4KUB
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BU of 4kub by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA
分子名称: 1,2-ETHANEDIOL, COENZYME A, GNAT superfamily acetyltransferase PA4794, ...
著者Majorek, K.A, Chruszcz, M, Osinski, T, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2013-05-21
公開日2013-06-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013
6J3P
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Crystal structure of the human GCN5 bromodomain in complex with compound (R,R)-36n
分子名称: 2-{[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methylpiperidin-3-yl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, Histone acetyltransferase KAT2A
著者Huang, L.Y, Li, H, Niu, L, Wu, C.Y, Yu, Y.M, Li, L.L, Yang, S.Y.
登録日2019-01-05
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.
J.Med.Chem., 62, 2019
5TRL
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BU of 5trl by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain
分子名称: Histone acetyltransferase KAT2A, SUCCINYL-COENZYME A
著者Guo, Y.R, Tao, Y.J.
登録日2016-10-26
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.
Nature, 552, 2017
5TRM
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BU of 5trm by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain
分子名称: Histone acetyltransferase KAT2A
著者Guo, Y.R, Tao, Y.J.
登録日2016-10-26
公開日2017-12-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.
Nature, 552, 2017
8HEH
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BU of 8heh by Molmil
Crystal structure of GCN5-related N-acetyltransferase 05790
分子名称: COENZYME A, GLYCEROL, GNAT family N-acetyltransferase
著者Xu, M.X, Ran, T.T, Wang, W.
登録日2022-11-08
公開日2022-12-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
1B87
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CRYSTAL STRUCTURE OF AN AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE
分子名称: ACETYL COENZYME *A, PROTEIN (AMINOGLYCOSIDE N6'-ACETYLTRANSFERASE TYPE 1)
著者Wybenga-Groot, L.E, Berghuis, A.M.
登録日1999-02-09
公開日1999-06-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold.
Structure Fold.Des., 7, 1999
1N71
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Crystal structure of aminoglycoside 6'-acetyltransferase type Ii in complex with coenzyme A
分子名称: COENZYME A, SULFATE ION, aac(6')-Ii
著者Burk, D.L, Ghuman, N, Wybenga-Groot, L.E, Berghuis, A.M.
登録日2002-11-12
公開日2003-03-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members
Protein Sci., 12, 2003
3KJL
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BU of 3kjl by Molmil
Sgf11:Sus1 complex
分子名称: Protein SUS1, SAGA-associated factor 11
著者Stewart, M, Ellisdon, A.M.
登録日2009-11-03
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1.
J.Biol.Chem., 285, 2010
3KIK
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BU of 3kik by Molmil
Sgf11:Sus1 complex
分子名称: Protein SUS1, SAGA-associated factor 11
著者Stewart, M, Ellisdon, A.M.
登録日2009-11-02
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the interaction between yeast Spt-Ada-Gcn5 acetyltransferase (SAGA) complex components Sgf11 and Sus1
J.Biol.Chem., 285, 2010
7N1L
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BU of 7n1l by Molmil
Crystal Structure of Ribosomal-protein-alanine N-acetyltransferase from Brucella melitensis biovar Abortus 2308
分子名称: GCN5-related N-acetyltransferase
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-05-27
公開日2021-06-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Ribosomal-protein-alanine N-acetyltransferase from Brucella melitensis biovar Abortus 2308
To be published
4LDF
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BU of 4ldf by Molmil
Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
分子名称: GCN5 like acetylase + bromodomain, GLYCEROL, UNKNOWN ATOM OR ION
著者Wernimont, A.K, Loppnau, P, Fonseca, M, Knapp, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Mottaghi, K, Structural Genomics Consortium (SGC)
登録日2013-06-24
公開日2013-07-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of CpBRD2 from cryptosporidium, cgd3_3190
TO BE PUBLISHED
8XJH
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BU of 8xjh by Molmil
Crystal structure of Arabidopsis N-amino acetyltransferase 2 (AtNATA2) bound to di-CoA
分子名称: GCN5-related N-acetyltransferase 8, GLYCEROL, [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate
著者Arold, S.T, Hameed, U.F.S.
登録日2023-12-21
公開日2024-12-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of Arabidopsis N-amino acetyltransferase 2 (AtNATA2) bound to di-CoA
To Be Published
8XJB
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Crystal structure of AtNATA2 bound to Spermine
分子名称: GCN5-related N-acetyltransferase 8, SPERMINE
著者Arold, S.T, Hameed, U.F.S.
登録日2023-12-21
公開日2024-12-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of AtNATA2 bound to Spermine
To Be Published
6GTS
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BU of 6gts by Molmil
Structure of the AtaT-AtaR complex bound DNA
分子名称: Acetyltransferase, DNA, DUF1778 domain-containing protein
著者Garcia-Pino, A, Jurenas, D.
登録日2018-06-19
公開日2019-03-06
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.357 Å)
主引用文献Mechanism of regulation and neutralization of the AtaR-AtaT toxin-antitoxin system.
Nat. Chem. Biol., 15, 2019
5JPH
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BU of 5jph by Molmil
Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus in complex with CoA
分子名称: Acetyltransferase SACOL1063, CHLORIDE ION, COENZYME A
著者Majorek, K.A, Osinski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-03
公開日2016-06-29
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
5JQ4
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BU of 5jq4 by Molmil
Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus
分子名称: 1,2-ETHANEDIOL, Acetyltransferase SACOL1063, CHLORIDE ION, ...
著者Majorek, K.A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-05-04
公開日2016-06-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
Biochim.Biophys.Acta, 1865, 2016
2VZZ
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BU of 2vzz by Molmil
Crystal structure of Rv0802c from Mycobacterium tuberculosis in Complex with Succinyl-CoA
分子名称: RV0802C, SUCCINYL-COENZYME A
著者Vetting, M.W, Errey, J.C, Blanchard, J.S.
登録日2008-08-07
公開日2009-04-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
2VZY
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Crystal structure of Rv0802c from Mycobacterium tuberculosis in an unliganded form.
分子名称: 2-ETHOXYETHANOL, ACETATE ION, CITRATE ANION, ...
著者Vetting, M.W, Errey, J.C, Blanchard, J.S.
登録日2008-08-07
公開日2009-04-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rv0802C from Mycobacterium Tuberculosis: The First Structure of a Succinyltransferase with the Gnat Fold.
Acta Crystallogr.,Sect.F, 64, 2008
3D7C
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Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2
分子名称: General control of amino acid synthesis protein 5-like 2
著者Filippakopoulos, P, Eswaran, J, Picaud, S, Fedorov, O, Murray, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2008-05-21
公開日2008-07-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
8H66
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Crystal structure of human GCN5 histone acetyltransferase domain bound with propionyl-CoA
分子名称: Histone acetyltransferase KAT2A, propionyl Coenzyme A
著者Li, N, Tao, Y.J, Guo, Y.R.
登録日2022-10-15
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications.
Res, 6, 2023

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