PDB: 136 件ウェブページステータス検索Chemie searchBIRD

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4MMS	Crystal Structure of Prefusion-stabilized RSV F Variant Cav1 at pH 5.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION 著者 Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.397 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMV	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 著者 Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2021-06-02 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMU	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ... 著者 Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMT	Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 9.5 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2 著者 Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
4MMQ	Crystal Structure of Prefusion-stabilized RSV F Variant DS 分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, SULFATE ION 著者 Mclellan, J.S, Joyce, M.G, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D. 登録日 2013-09-09 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.253 Å) 主引用文献 Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science, 342, 2013
5TDL	Crystal structure of prefusion-stabilized bovine RSV fusion glycoprotein (single-chain DS2-v1 variant: strain 391-2 sc9 DS-Cav1 Q98C Q361C) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bovine prefusion RSV F glycoprotein 著者 Chen, L, Zhang, B, Kwong, P.D. 登録日 2016-09-19 公開日 2017-08-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Protection of calves by a prefusion-stabilized bovine RSV F vaccine. NPJ Vaccines, 2, 2017
5C69	Crystal Structure of Prefusion-stabilized RSV F variant PR-DM 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Fusion glycoprotein F0,Fibritin, ... 著者 McLellan, J.S, Langedijk, J.P.M. 登録日 2015-06-22 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nat Commun, 6, 2015
5TOJ	Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... 著者 Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. 登録日 2016-10-17 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
5TOK	Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... 著者 Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. 登録日 2016-10-17 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
5UDC	Crystal Structure of RSV F A2 Bound to MEDI8897 分子名称: CHLORIDE ION, Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, ... 著者 McLellan, J.S. 登録日 2016-12-26 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants. Sci Transl Med, 9, 2017
5EA6	Crystal Structure of Inhibitor BTA-9881 in Complex with Prefusion RSV F Glycoprotein 分子名称: (9~{b}~{R})-9~{b}-(4-chlorophenyl)-1-pyridin-3-ylcarbonyl-2,3-dihydroimidazo[5,6]pyrrolo[1,2-~{a}]pyridin-5-one, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5EA8	Crystal Structure of Prefusion RSV F Glycoprotein Fusion Inhibitor Resistance Mutant D489Y 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, D(-)-TARTARIC ACID, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5EA7	Crystal Structure of Inhibitor BMS-433771 in Complex with Prefusion RSV F Glycoprotein 分子名称: 1-cyclopropyl-3-[[1-(4-oxidanylbutyl)benzimidazol-2-yl]methyl]imidazo[4,5-c]pyridin-2-one, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5EA4	Crystal Structure of Inhibitor JNJ-49153390 in Complex with Prefusion RSV F Glycoprotein 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 3-[[5-bromanyl-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-1-cyclopropyl-imidazo[4,5-c]pyridin-2-one, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5EA3	Crystal Structure of Inhibitor JNJ-2408068 in Complex with Prefusion RSV F Glycoprotein 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[2-[[1-(2-azanylethyl)piperidin-4-yl]amino]-4-methyl-benzimidazol-1-yl]methyl]-6-methyl-pyridin-3-ol, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Langedijk, J.P, Roymans, D. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5EA5	Crystal Structure of Inhibitor TMC-353121 in Complex with Prefusion RSV F Glycoprotein 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol, D(-)-TARTARIC ACID, ... 著者 Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. 登録日 2015-10-15 公開日 2015-12-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
5U68	Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus 分子名称: Chimera protein of Fusion glycoprotein F0 and Envelope glycoprotein, MPE8 著者 Wen, X, Jardetzky, T.S. 登録日 2016-12-07 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.083 Å) 主引用文献 Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus. Nat Microbiol, 2, 2017
5TPN	Crystal structure of RSV F in complex with human antibody hRSV90 分子名称: Fusion glycoprotein F0,Fibritin, hRSV0 light chain, hRSV90 heavy chain 著者 Mousa, J.J, Crowe, J.E. 登録日 2016-10-20 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.141 Å) 主引用文献 Crystal structure of RSV F in complex with human antibody hRSV90 To Be Published
5W23	Crystal Structure of RSV F in complex with 5C4 Fab 分子名称: 5C4 Fab heavy chain, 5C4 Fab light chain, Fusion glycoprotein F0, ... 著者 Battles, M.B, McLellan, J.S. 登録日 2017-06-05 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis of respiratory syncytial virus subtype-dependent neutralization by an antibody targeting the fusion glycoprotein. Nat Commun, 8, 2017
5C6B	Crystal Structure of Prefusion-stabilized RSV F variant SC-TM 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Fusion glycoprotein F0,Fibritin, ... 著者 McLellan, J.S, Langedijk, J.P.M. 登録日 2015-06-22 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. Nat Commun, 6, 2015
5EVM	Crystal Structure of Nipah Virus Fusion Glycoprotein in the Prefusion State 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MALONATE ION, ... 著者 Xu, K, Nikolov, D.B. 登録日 2015-11-20 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.367 Å) 主引用文献 Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. Plos Pathog., 11, 2015
4E0R	Structure of the chicken MHC class I molecule BF2*0401 分子名称: 8-MERIC PEPTIDE (FUS/TLS), Beta-2 microglobulin, MHC class I alpha chain 2 著者 Zhang, J, Chen, Y, Qi, J, Gao, F, Kaufman, J, Xia, C, Gao, G.F. 登録日 2012-03-05 公開日 2012-11-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens. J.Immunol., 189, 2012
4ZYP	Crystal Structure of Motavizumab and Quaternary-Specific RSV-Neutralizing Human Antibody AM14 in Complex with Prefusion RSV F Glycoprotein 分子名称: AM14 antibody Fab heavy chain, AM14 antibody light chain, Fusion glycoprotein F0,Fibritin, ... 著者 Gilman, M.S.A, McLellan, J.S. 登録日 2015-05-21 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein. Plos Pathog., 11, 2015
6W52	Prefusion RSV F bound by neutralizing antibody RSB1 分子名称: Fusion glycoprotein F0, Fusion glycoprotein F1 fused with Fibritin trimerization domain, RSB1 Fab Heavy Chain, ... 著者 Harshbarger, W, Chandramouli, S, Malito, M. 登録日 2020-03-12 公開日 2020-11-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F. Plos Pathog., 16, 2020
8ONS	TAF15 amyloid fold in atypical FTLD - Individual 1 分子名称: TATA-binding protein-associated factor 2N 著者 Tetter, S, Ryskeldi-Falcon, B. 登録日 2023-04-03 公開日 2023-12-06 最終更新日 2024-02-07 実験手法 ELECTRON MICROSCOPY (1.97 Å) 主引用文献 TAF15 amyloid filaments in frontotemporal lobar degeneration. Nature, 625, 2024

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