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8CEB
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Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
分子名称: Alpha-synuclein
著者Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Sew, P.C, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
登録日2023-02-01
公開日2023-03-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
2H6Q
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me3 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-06-01
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H68
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6K
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H9L
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WDR5delta23
分子名称: SULFATE ION, WD-repeat protein 5
著者Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2006-06-10
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for molecular recognition and presentation of histone H3 By WDR5.
Embo J., 25, 2006
2GLI
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BU of 2gli by Molmil
FIVE-FINGER GLI/DNA COMPLEX
分子名称: COBALT (II) ION, DNA (5'-D(*AP*CP*GP*TP*GP*GP*AP*CP*CP*AP*CP*CP*CP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*GP*TP*CP*TP*TP*GP*GP*GP*TP*GP*GP*TP*CP*CP*AP*CP*G)-3'), ...
著者Pavletich, N.P, Pabo, C.O.
登録日1993-11-09
公開日1993-11-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Science, 261, 1993
2H6N
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
1XCQ
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Complex HCV core-Fab 19D9D6-Protein L mutant (D55A,L57H,Y64W) in space group P21
分子名称: Capsid protein C, Monoclonal antibody 19D9D6 Heavy chain, Monoclonal antibody 19D9D6 Light chain, ...
著者Menez, R, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A.
登録日2004-09-03
公開日2005-05-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Different crystal packing in Fab-protein L semi-disordered peptide complex.
Acta Crystallogr.,Sect.D, 61, 2005
1XCT
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Complex HCV core-Fab 19D9D6-Protein L mutant (D55A, L57H, Y64W) in space group P21212
分子名称: Capsid protein C, Monoclonal antibody 19D9D6 Heavy chain, Monoclonal antibody 19D9D6 Light chain, ...
著者Menez, R, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A.
登録日2004-09-03
公開日2005-05-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Different crystal packing in Fab-protein L semi-disordered peptide complex.
Acta Crystallogr.,Sect.D, 61, 2005
8CR8
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BU of 8cr8 by Molmil
human Interleukin-23
分子名称: Interleukin-12 subunit beta, Interleukin-23 subunit alpha, TERBIUM(III) ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-03-08
公開日2024-02-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
2FHY
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Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor
分子名称: 2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Abad-Zapatero, C.
登録日2005-12-27
公開日2006-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode.
Bioorg.Med.Chem.Lett., 16, 2006
8FUQ
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BU of 8fuq by Molmil
Crystal structure of rabies virus (strain CVS-11) P3 dimerization domain
分子名称: Phosphoprotein
著者Donnelly, C.M, Cross, E.M, Forwood, J.K.
登録日2023-01-18
公開日2023-01-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of rabies virus (strain CVS-11) P3 dimerization domain
To Be Published
2HIO
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BU of 2hio by Molmil
HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN
分子名称: PROTEIN (HISTONE H2A), PROTEIN (HISTONE H2B), PROTEIN (HISTONE H3), ...
著者Arents, G, Moudrianakis, E.N.
登録日1999-06-15
公開日2000-01-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix.
Proc.Natl.Acad.Sci.USA, 88, 1991
2HI3
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Solution structure of the homeodomain-only protein HOP
分子名称: Homeodomain-only protein
著者Mackay, J.P, Kook, H, Epstein, J.A, Simpson, R.J, Yung, W.W.
登録日2006-06-28
公開日2007-01-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Analysis of the structure and function of the transcriptional coregulator HOP
Biochemistry, 45, 2006
2NOZ
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Structure of Q315F human 8-oxoguanine glycosylase distal crosslink to 8-oxoguanine DNA
分子名称: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
著者Radom, C.T, Banerjee, A, Verdine, G.L.
登録日2006-10-26
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
8D5E
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The complex of Gtf2b Peptide TGAASFDEF Presented by H2-Dd
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Custodio, J.M.F, Baker, B.M.
登録日2022-06-04
公開日2022-07-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
8D5F
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BU of 8d5f by Molmil
The complex of Gtf2b neoantigen TGAARFDEF Presented by H2-Dd
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Custodio, J.M.F, Baker, B.M.
登録日2022-06-04
公開日2022-07-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
2NOF
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BU of 2nof by Molmil
Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA
分子名称: 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
著者Radom, C.T, Banerjee, A, Verdine, G.L.
登録日2006-10-25
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
2NOB
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Structure of catalytically inactive H270A human 8-oxoguanine glycosylase crosslinked to 8-oxoguanine DNA
分子名称: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*T*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
著者Radom, C.T, Banerjee, A, Verdine, G.L.
登録日2006-10-25
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
2G9A
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Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
分子名称: Histone H3, WD-repeat protein 5
著者Chai, J, Han, Z, Wang, H, Shen, Y.
登録日2006-03-06
公開日2006-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
To be published
2NOI
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Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA
分子名称: 5'-D(*GP*CP*GP*TP*C*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
著者Radom, C.T, Banerjee, A, Verdine, G.L.
登録日2006-10-25
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
2NOE
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BU of 2noe by Molmil
Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA
分子名称: 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ...
著者Radom, C.T, Banerjee, A, Verdine, G.L.
登録日2006-10-25
公開日2006-11-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations.
J.Biol.Chem., 282, 2007
6GHO
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Crystal structure of Spx in complex with YjbH
分子名称: CHLORIDE ION, Regulatory protein Spx, UPF0413 protein GK0824
著者Awad, W, Logan, D.T, von Wachenfeldt, C.
登録日2018-05-08
公開日2019-04-24
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis for YjbH Adaptor-Mediated Recognition of Transcription Factor Spx.
Structure, 27, 2019
8D6A
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BU of 8d6a by Molmil
Cryo-EM structure of human LIF signaling complex: model containing the interaction core region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6 receptor subunit beta, ...
著者Zhou, Y, Franklin, M.C.
登録日2022-06-06
公開日2023-03-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural insights into the assembly of gp130 family cytokine signaling complexes.
Sci Adv, 9, 2023
8UQE
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Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density)
分子名称: E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E
著者Hu, Q, Botuyan, M.V, Mer, G.
登録日2023-10-23
公開日2024-01-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.562 Å)
主引用文献Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024

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