PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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2O2I	Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,3-propandiol 分子名称: 1,3-PROPANDIOL, BROMIDE ION, Haloalkane dehalogenase 3 著者 Mazumdar, P.A, Hulecki, J, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC) 登録日 2006-11-29 公開日 2007-11-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of haloalkane dehalogenase Rv2579 from Mycobacterium tuberculosis complexed with 1,3-propandiol To be Published
4DE2	CTX-M-9 class A beta-lactamase complexed with compound 12 分子名称: 3-[(dimethylamino)methyl]-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide, Beta-lactamase, DIMETHYL SULFOXIDE 著者 Nichols, D.A, Chen, Y. 登録日 2012-01-19 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase J.Med.Chem., 55, 2012
3SWK	Crystal structure of vimentin coil1B fragment 分子名称: Vimentin 著者 Chernyatina, A.A, Strelkov, S.V. 登録日 2011-07-14 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly. Proc.Natl.Acad.Sci.USA, 109, 2012
3GZ4	Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH 分子名称: Hypothetical oxidoreductase yciK, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-04-06 公開日 2009-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH To be Published
4DR5	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, crystallographically disordered cognate transfer RNA anticodon stem-loop and streptomycin bound 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
3GTY	Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone 分子名称: 30S ribosomal protein S7, Trigger factor 著者 Martinez-Hackert, E, Hendrickson, W.A. 登録日 2009-03-28 公開日 2009-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Promiscuous substrate recognition in folding and assembly activities of the trigger factor chaperone Cell(Cambridge,Mass.), 138, 2009
4HR2	Structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-10-26 公開日 2012-11-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to ADP To be Published
3SVG	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand 分子名称: (1R)-1-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxyphenyl]ethanol, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 著者 Filippakopoulos, P, Picaud, S, Felletar, I, Hewings, S.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Conway, S.J, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-07-12 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand TO BE PUBLISHED
4DGC	TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex 分子名称: TRIMCyp, cyclosporin A 著者 Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. 登録日 2012-01-25 公開日 2012-02-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012
2O4L	Crystal Structure of HIV-1 Protease (Q7K, I50V) in Complex with Tipranavir 分子名称: CHLORIDE ION, GLYCEROL, N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE, ... 著者 Armstrong, A.A, Muzammil, S, Jakalian, A, Bonneau, P.R, Schmelmer, V, Freire, E, Amzel, L.M. 登録日 2006-12-04 公開日 2006-12-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Unique thermodynamic response of tipranavir to human immunodeficiency virus type 1 protease drug resistance mutations. J.Virol., 81, 2007
3SVT	Structure of a short-chain type dehydrogenase/reductase from Mycobacterium ulcerans 分子名称: CHLORIDE ION, SODIUM ION, Short-chain type dehydrogenase/reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-07-12 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2I51	CRYSTAL STRUCTURE OF a pyridoxamine 5'-phosphate oxidase-related, FMN binding protein (NPUN_F5749) FROM NOSTOC PUNCTIFORME PCC 73102 AT 1.40 A RESOLUTION 分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-08-23 公開日 2006-09-05 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of Uncharacterized conserved protein of COG5135 (ZP_00109616.1) from Nostoc punctiforme PCC 73102 at 1.40 A resolution To be published
3GVC	Crystal structure of probable short-chain dehydrogenase-reductase from Mycobacterium tuberculosis 分子名称: Probable short-chain type dehydrogenase/reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-03-30 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3H1P	Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site 分子名称: Caspase-7, N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-[(2S)-1-CARBOXY-3-HYDROXYPROPAN-2-YL]-L-VALINAMIDE 著者 Witkowski, W.A, Hardy, J.A. 登録日 2009-04-13 公開日 2009-06-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 L2' loop is critical for caspase-7 active site formation. Protein Sci., 18, 2009
4HTR	N149W variant of SiRHP bound to sulfite 分子名称: IRON/SULFUR CLUSTER, SIROHEME, SODIUM ION, ... 著者 Smith, K.W, Stroupe, M.E. 登録日 2012-11-01 公開日 2013-01-16 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mutational analysis of sulfite reductase hemoprotein reveals the mechanism for coordinated electron and proton transfer. Biochemistry, 51, 2012
4HU9	E. coli thioredoxin variant with (4S)-FluoroPro76 as single proline residue 分子名称: COPPER (II) ION, Thioredoxin-1 著者 Scharer, M.A, Rubini, M, Capitani, G, Glockshuber, R. 登録日 2012-11-02 公開日 2013-05-29 最終更新日 2017-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 (4R)- and (4S)-Fluoroproline in the Conserved cis-Prolyl Peptide Bond of the Thioredoxin Fold: Tertiary Structure Context Dictates Ring Puckering. Chembiochem, 14, 2013
4DJY	Structure of BACE Bound to (R)-5-cyclopropyl-2-imino-3-methyl-5-(3-(5-(prop-1-yn-1-yl)pyridin-3-yl)phenyl)imidazolidin-4-one 分子名称: (2E,5R)-5-cyclopropyl-2-imino-3-methyl-5-{3-[5-(prop-1-yn-1-yl)pyridin-3-yl]phenyl}imidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID 著者 Strickland, C, Cumming, J. 登録日 2012-02-02 公開日 2012-03-21 最終更新日 2012-04-04 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
3H3S	Crystal structure of the CERT START domain in complex with HPA-15 分子名称: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]pentadecanamide 著者 Kudo, N, Wakatsuki, S, Kato, R. 登録日 2009-04-17 公開日 2010-03-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
4HWG	Structure of UDP-N-acetylglucosamine 2-epimerase from Rickettsia bellii 分子名称: PHOSPHATE ION, UDP-N-acetylglucosamine 2-epimerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-07 公開日 2012-11-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of UDP-N-acetylglucosamine 2-epimerase from Rickettsia bellii TO BE PUBLISHED
3T3Y	Crystal structure of AlkB in complex with Fe(III) and 2-(3-hydroxypicolinomido)acetic acid 分子名称: Alpha-ketoglutarate-dependent dioxygenase AlkB, FE (III) ION, N-[(3-hydroxypyridin-2-yl)carbonyl]glycine 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2011-07-25 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate-dependent nucleic Acid demethylase. J.Med.Chem., 55, 2012
4DLZ	H-Ras Set 2 Ca(OAc)2/DTE, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.662 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
3H5G	Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides. 分子名称: ACETATE ION, COIL SER L16D-Pen, ZINC ION 著者 Peacock, A.F.A, Stuckey, J.A, Pecoraro, V.L. 登録日 2009-04-22 公開日 2009-07-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides. Angew.Chem.Int.Ed.Engl., 48, 2009
4HWP	Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(4-amino-2-methylquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.807 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
3T46	Crystal structure of Staphylococcal Complement Inhibitor D (SCIN-D) at 1.5 Angstrom 分子名称: SCIN-D, SODIUM ION 著者 Garcia, B.L, Geisbrecht, B.V, Summers, B.J. 登録日 2011-07-25 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287, 2012
3T49	Crystal structure of truncated form of Staphylococcal Complement Inhibitor B (SCIN-B) at 1.5 Angstrom 分子名称: Fibrinogen-binding protein, GLYCEROL, SULFATE ION 著者 Garcia, B.L, Geisbrecht, B.V, Summers, B.J. 登録日 2011-07-25 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287, 2012

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