PDB: 19326 件ウェブページステータス検索Chemie searchBIRD

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4DE1	CTX-M-9 class A beta-lactamase complexed with compound 18 分子名称: Beta-lactamase, DIMETHYL SULFOXIDE, N-[3-(1H-tetrazol-5-yl)phenyl]-2H-indazole-5-carboxamide 著者 Nichols, D.A, Chen, Y. 登録日 2012-01-19 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase J.Med.Chem., 55, 2012
4DYS	Crystal Structure of Apo Swine Flu Influenza Nucleoprotein 分子名称: Nucleocapsid protein 著者 Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. 登録日 2012-02-29 公開日 2013-03-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 To be determined To be Published
4DEH	Crystal structure of c-Met in complex with triazolopyridinone inhibitor 3 分子名称: 5-phenyl-3-(quinolin-6-ylmethyl)-3,5,6,7-tetrahydro-4H-[1,2,3]triazolo[4,5-c]pyridin-4-one, Hepatocyte growth factor receptor 著者 Whittington, D.A, Bellon, S.F, Long, A.M. 登録日 2012-01-20 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
4DET	Crystal Structure of the Wild Type TTR Binding Kaempferol (TTRwt:KAE) 分子名称: 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, Transthyretin 著者 Trivella, D.B.B, Polikarpov, I. 登録日 2012-01-22 公開日 2012-11-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis. J.Struct.Biol., 180, 2012
4DF9	Crystal structure of a putative peptidase (BF3526) from Bacteroides fragilis NCTC 9343 at 2.17 A resolution 分子名称: CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-01-23 公開日 2012-02-15 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Crystal structure of a putative peptidase (BF3526) from Bacteroides fragilis NCTC 9343 at 2.17 A resolution To be published
4DGB	TRIMCyp cyclophilin domain from Macaca mulatta: HIV-2 CA cyclophilin-binding loop complex 分子名称: TRIMCyp, capsid protein 著者 Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. 登録日 2012-01-25 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012
4DGM	Crystal Structure of maize CK2 in complex with the inhibitor apigenin 分子名称: 1,2-ETHANEDIOL, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Casein kinase II subunit alpha, ... 著者 Lolli, G, Mazzorana, M, Battistutta, R. 登録日 2012-01-26 公開日 2012-08-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Inhibition of protein kinase CK2 by flavonoids and tyrphostins. A structural insight. Biochemistry, 51, 2012
4E0W	Crystal structure of the kainate receptor GluK3 ligand binding domain in complex with kainate 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, Glutamate receptor, ... 著者 Venskutonyte, R, Frydenvang, K, Kastrup, J.S. 登録日 2012-03-05 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3501 Å) 主引用文献 Kainate induces various domain closures in AMPA and kainate receptors. Neurochem Int, 61, 2012
4E18	Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin 分子名称: Catenin alpha-1, Vinculin 著者 Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I. 登録日 2012-03-05 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin To be Published
4DAB	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with hypoxanthine 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DK9	Crystal Structure of MBD4 Catalytic Domain Bound to Abasic DNA 分子名称: 5'-D(*AP*AP*GP*AP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3', Methyl-CpG-binding domain protein 4, ... 著者 Manvilla, B.A, Toth, E.A, Drohat, A.C. 登録日 2012-02-03 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA. J.Mol.Biol., 420, 2012
8VMB	The crystal structure of rhinovirus C15 RNA replication element sB-loop mutant in complex with Fab BL3-6 分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (83-MER) 著者 Das, N.K, Koirala, D. 登録日 2024-01-13 公開日 2024-07-24 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis for a highly conserved RNA-mediated enteroviral genome replication. Nucleic Acids Res., 2024
4DL5	Human DNA polymerase eta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2). 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*TP*AP*CP*GP*GP*TP*CP*AP*CP*AP*CP*T)-3'), ... 著者 Zhao, Y, Biertumpfel, C, Gregory, M, Hanaoka, F, Hua, Y, Yang, W. 登録日 2012-02-05 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structural Basis for Chemoresistance to Cisplatin Mediated by DNA Polymerase eta Proc.Natl.Acad.Sci.USA, 109, 2012
4DLI	Human p38 MAP kinase in complex with RL87 分子名称: Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine 著者 Gruetter, C, Getlik, M, Simard, J.R, Rauh, D. 登録日 2012-02-06 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38alpha kinase. Plos One, 7, 2012
4DLR	H-Ras PEG 400/Ca(OAc)2, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.319 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DLY	Set 1 CaCl2/DTT, ordered off 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2012-02-06 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
4DG5	Crystal structure of staphylococcal Phosphoglycerate kinase 分子名称: Phosphoglycerate kinase 著者 Roychowdhury, A, Mukherjee, S, Dutta, D, Das, A.K. 登録日 2012-01-25 公開日 2013-01-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure based functional analysis of Staphylococcal Phosphoglycerate kinase To be Published
4DGU	Crystal structure of a putative cell adhesion protein (BT0320) from Bacteroides thetaiotaomicron VPI-5482 at 2.37 A resolution 分子名称: CHLORIDE ION, ZINC ION, putative cell adhesion protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-01-26 公開日 2012-02-15 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 A Distinct Type of Pilus from the Human Microbiome. Cell, 165, 2016
4DNI	Structure of Editosome protein 分子名称: Fusion protein of RNA-editing complex proteins MP42 and MP18 著者 Park, Y.-J, Hol, W. 登録日 2012-02-08 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds. J.Struct.Biol., 180, 2012
4DHV	Crystal structure of the Pyrococcus furiosus ferredoxin D14C variant containing the heterometallic [AgFe3S4] cluster 分子名称: COBALT HEXAMMINE(III), Ferredoxin, SILVER/IRON/SULFUR CLUSTER 著者 Jakab-Simon, I.N, Christensen, H.E.M, Haahr, L.T. 登録日 2012-01-30 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Heterometallic [AgFe(3)S (4)] ferredoxin variants: synthesis, characterization, and the first crystal structure of an engineered heterometallic iron-sulfur protein. J.Biol.Inorg.Chem., 18, 2013
4DI2	Crystal structure of BACE1 in complex with hydroxyethylamine inhibitor 37 分子名称: (2R)-N-{(2S,3R)-4-{[(4'S)-6'-(2,2-dimethylpropyl)-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl]amino}-3-hydroxy-1-[3-(1,3-thiazol-2-yl)phenyl]butan-2-yl}-2-methoxypropanamide, Beta-secretase 1, GLYCEROL 著者 Whittington, D.A, Long, A.M. 登録日 2012-01-30 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and synthesis of potent, orally efficacious hydroxyethylamine derived beta-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. J.Med.Chem., 55, 2012
4DQ5	Structural Investigation of Bacteriophage Phi6 Lysin (WT) 分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Membrane protein Phi6 P5wt 著者 Dessau, M.A, Modis, Y. 登録日 2012-02-15 公開日 2013-01-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.395 Å) 主引用文献 Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme. PLoS Genet, 8, 2012
5U2N	Crystal structure of human NAMPT with A-1326133 分子名称: N-{4-[1-(2-methylpropanoyl)piperidin-4-yl]phenyl}-2H-pyrrolo[3,4-c]pyridine-2-carboxamide, Nicotinamide phosphoribosyltransferase, SULFATE ION 著者 Longenecker, K.L, Raich, D, Korepanova, A.V. 登録日 2016-11-30 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Mol. Cancer Ther., 16, 2017
8VM8	The crystal structure of coxsackievirus B3 RNA replication element sD-loop mutant in complex with Fab BL3-6 分子名称: Heavy Chain of Fab BL3-6, Light Chain of Fab BL3-6, RNA (93-MER) 著者 Das, N.K, Koirala, D. 登録日 2024-01-13 公開日 2024-07-24 最終更新日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural basis for a highly conserved RNA-mediated enteroviral genome replication. Nucleic Acids Res., 2024
4DQF	Crystal Structure of (G16A/L38A) HIV-1 Protease in Complex with DRV 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, 1,2-ETHANEDIOL, Aspartyl protease, ... 著者 Schiffer, C.A, Mittal, S. 登録日 2012-02-15 公開日 2012-03-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J.Am.Chem.Soc., 134, 2012

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