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5YPX
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Crystal structure of calaxin with magnesium
分子名称: Calaxin, MAGNESIUM ION
著者Shojima, T, Hou, F, Takahashi, Y, Okai, M, Mizuno, K, Inaba, K, Miyakawa, T, Tanokura, M.
登録日2017-11-04
公開日2018-03-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition
Sci Rep, 8, 2018
4YLH
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Crystal structure of DpgC with bound substrate analog and Xe on oxygen diffusion pathway
分子名称: DpgC, XENON, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Li, K, Di Russo, N.V, Condurso, H.L, Roitberg, A.E, Bruner, S.D.
登録日2015-03-05
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Oxygen diffusion pathways in a cofactor-independent dioxygenase.
Chem Sci, 6, 2015
4YLZ
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Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lacto-N-neotetraose (LNnT)
分子名称: GLYCEROL, Galectin-4, SULFATE ION, ...
著者Bum-Erdene, K, Blanchard, H.
登録日2015-03-06
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens.
Febs J., 282, 2015
5Y7C
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BU of 5y7c by Molmil
Hapalindole A and DMSPP Bound AmbP3
分子名称: AmbP3, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Hapalindole A
著者Wong, C.P, Awakawa, T, Nakashima, Y.
登録日2017-08-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3
Angew. Chem. Int. Ed. Engl., 57, 2018
4YWC
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Crystal structure of Myc3(5-242) fragment in complex with Jaz9(218-239) peptide
分子名称: Protein TIFY 7, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J.S, Xu, H.E, Melcher, K, He, S.Y.
登録日2015-03-20
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YRK
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BU of 4yrk by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with (4-chlorophenyl)methanol (Chem 260)
分子名称: (4-chlorophenyl)methanol, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5Y8C
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Crystal Structure Analysis of the BRD4
分子名称: 1,2-ETHANEDIOL, 5-chloranyl-2-methoxy-N-(6-methoxy-3-methyl-1,2-benzoxazol-5-yl)benzenesulfonamide, Bromodomain-containing protein 4, ...
著者Xu, Y, Zhang, Y, Song, M, Wang, C.
登録日2017-08-21
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC)
J. Med. Chem., 61, 2018
4YCP
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E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp
分子名称: FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, SULFATE ION, ...
著者Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A.
登録日2015-02-20
公開日2015-04-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
5YBT
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Fe(II)/(alpha)ketoglutarate-dependent dioxygenase PrhA-V150L/A232S/M241V in complex with berkeleyone A
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, PrhA, ...
著者Nakashima, Y, Senda, M.
登録日2017-09-05
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
Nat Commun, 9, 2018
4YWF
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AbyA5
分子名称: AbyA5
著者Byrne, M.J, Race, P.R.
登録日2015-03-20
公開日2016-06-29
最終更新日2019-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis.
Angew.Chem.Int.Ed.Engl., 58, 2019
5YCT
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Engineered hairpin loop3 mutant monomer in Single-chain Monellin
分子名称: Single chain Monellin
著者Surana, P, Nandwani, N, Udgaonkar, J.B, Gosavi, S, Das, R.
登録日2017-09-08
公開日2018-11-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献A five-residue motif for the design of domain swapping in proteins.
Nat Commun, 10, 2019
4YIC
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CRYSTAL STRUCTURE OF A TRAP TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM BORDETELLA BRONCHISEPTICA RB50 (BB0280, TARGET EFI-500035) WITH BOUND PICOLINIC ACID
分子名称: ACETATE ION, CALCIUM ION, IMIDAZOLE, ...
著者Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Koss, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2015-03-01
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献CRYSTAL STRUCTURE OF A TRAP TRANSPORTER SOLUTE BINDING PROTEIN (IPR025997) FROM BORDETELLA BRONCHISEPTICA RB50 (BB0280, TARGET EFI-500035) WITH BOUND PICOLINIC ACID
To be published
4YMK
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Crystal Structure of Stearoyl-Coenzyme A Desaturase 1
分子名称: Acyl-CoA desaturase 1, STEAROYL-COENZYME A, ZINC ION, ...
著者Bai, Y, McCoy, J.G, Rajashankar, K.R, Zhou, M.
登録日2015-03-06
公開日2015-06-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.605 Å)
主引用文献X-ray structure of a mammalian stearoyl-CoA desaturase.
Nature, 524, 2015
4YBZ
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BU of 4ybz by Molmil
Ca. Korarchaeum cryptofilum dinucleotide forming Acetyl-coenzyme A synthetase 1 in complex with ADP and with phosphorylated phosphohistidine segment (site I orientation)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, alpha subunit of Acyl-CoA synthetase (NDP forming), ...
著者Weisse, R.H.-J, Scheidig, A.J.
登録日2015-02-19
公開日2016-01-27
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangement for phosphoryl transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
5YBS
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Fe(II)/(alpha)ketoglutarate-dependent dioxygenase PrhA-V150L/A232S in complex with berkeleyone A
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, PrhA, ...
著者Nakashima, Y, Senda, M.
登録日2017-09-05
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
Nat Commun, 9, 2018
5YC5
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Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, ...
著者Caaveiro, J.M.M, Tamura, H, Tsumoto, K, Kiyoshi, M.
登録日2017-09-06
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered Fc gamma Receptor IIIa-Immobilized Column.
Sci Rep, 8, 2018
4YEW
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BU of 4yew by Molmil
HUab-19bp
分子名称: DNA-binding protein HU-alpha, DNA-binding protein HU-beta, synthetic DNA strand
著者Hammel, M, Reyes, F.E, Parpana, R, Tainer, J.A, Adhya, S, Amlanjyoti, D.
登録日2015-02-24
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.683 Å)
主引用文献HU multimerization shift controls nucleoid compaction.
Sci Adv, 2, 2016
5YFU
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Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate and AMP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, POTASSIUM ION, ...
著者Gogoi, P, Kanaujia, S.P.
登録日2017-09-22
公開日2018-02-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YG8
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Crystal structure of ribose-1,5-bisphosphate isomerase from Pyrococcus horikoshii OT3 in complex with ribulose-1,5-bisphosphate, AMP and GMP
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ...
著者Gogoi, P, Kanaujia, S.P.
登録日2017-09-22
公開日2018-02-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A presumed homologue of the regulatory subunits of eIF2B functions as ribose-1,5-bisphosphate isomerase in Pyrococcus horikoshii OT3.
Sci Rep, 8, 2018
5YLC
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BU of 5ylc by Molmil
Crystal Structure of MCR-1 Catalytic Domain
分子名称: Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION
著者Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L.
登録日2017-10-17
公開日2017-11-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance.
FASEB J., 32, 2018
5YOD
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Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
分子名称: BENZOIC ACID, NS2B cofactor, NS3 protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YPY
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Crystal structure of IlvN. Val-1c
分子名称: Acetolactate synthase isozyme 1 small subunit, VALINE
著者Sarma, S.P, Bansal, A, Schindelin, H, Demeler, B.
登録日2017-11-04
公開日2018-09-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.966 Å)
主引用文献Crystallographic Structures of IlvN·Val/Ile Complexes: Conformational Selectivity for Feedback Inhibition of Aceto Hydroxy Acid Synthases.
Biochemistry, 58, 2019
4Y8A
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Crystal Structure of the N-terminal domain of CEACAM6
分子名称: Carcinoembryonic antigen-related cell adhesion molecule 6, GLYCEROL, ZINC ION
著者Bonsor, D.A, Sundberg, E.J.
登録日2015-02-16
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YP2
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Cleavage of nicotinamide adenine dinucleotides by the ribosome inactivating protein from Momordica charantia
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NICOTINAMIDE, Ribosome-inactivating protein momordin I
著者Vinkovic, M, Hussain, J, Wood, G.E, Gill, R, Wood, S.P.
登録日2015-03-12
公開日2015-05-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
5YBN
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Fe(II)/(alpha)ketoglutarate-dependent dioxygenase PrhA in complex with (alpha)ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, PrhA
著者Nakashima, Y, Senda, M.
登録日2017-09-05
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.104 Å)
主引用文献Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.
Nat Commun, 9, 2018

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