PDB: 1140 件ウェブページステータス検索Chemie searchBIRD

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6QYG	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mg2+ and CoA. 分子名称: COENZYME A, MAGNESIUM ION, Possible 4'-phosphopantetheinyl transferase 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-08 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
5KIR	The Structure of Vioxx Bound to Human COX-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, GLYCEROL, ... 著者 Orlando, B.J, Malkowski, M.G. 登録日 2016-06-16 公開日 2016-09-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.697 Å) 主引用文献 Crystal structure of rofecoxib bound to human cyclooxygenase-2. Acta Crystallogr.,Sect.F, 72, 2016
8TIM	TRIOSE PHOSPHATE ISOMERASE 分子名称: SULFATE ION, TRIOSE PHOSPHATE ISOMERASE 著者 Artymiuk, P.J, Taylor, W.R, Phillips, D.C. 登録日 1998-08-25 公開日 1999-02-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Triose Phosphate Isomerase To be Published
5I6I	Crystal structure of a dBCCP-variant of Chaetomium thermophilum acetyl-CoA carboxylase 分子名称: Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein 著者 Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T. 登録日 2016-02-16 公開日 2016-04-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (8.4 Å) 主引用文献 The dynamic organization of fungal acetyl-CoA carboxylase. Nat Commun, 7, 2016
7AOI	Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate 分子名称: 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... 著者 Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. 登録日 2020-10-14 公開日 2020-12-02 最終更新日 2021-03-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. Embo J., 40, 2021
5IR5	Crystal structure of wild-type bacterial lipoxygenase from Pseudomonas aeruginosa PA-LOX with space group P21212 at 1.9 A resolution 分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, Arachidonate 15-lipoxygenase, FE (II) ION, ... 著者 Kalms, J, Banthiya, S, Galemou Yoga, E, Kuhn, H, Scheerer, P. 登録日 2016-03-12 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Biochim.Biophys.Acta, 1861, 2016
5IR4	Crystal structure of wild-type bacterial lipoxygenase from Pseudomonas aeruginosa PA-LOX with space group C2221 at 1.48 A resolution 分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradec-5-enoyloxy)propyl (11Z)-octadec-11-enoate, Arachidonate 15-lipoxygenase, CHLORIDE ION, ... 著者 Kalms, J, Banthiya, S, Galemou Yoga, E, Kuhn, H, Scheerer, P. 登録日 2016-03-12 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa. Biochim.Biophys.Acta, 1861, 2016
6YXX	State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate 分子名称: 12S ribosomal RNA, 50S ribosomal protein L13, putative, ... 著者 Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. 登録日 2020-05-04 公開日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
7TGH	Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... 著者 Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A. 登録日 2022-01-07 公開日 2022-04-06 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism. Science, 376, 2022
3HNZ	Structure of E. coli FabF(C163A) in Complex with Platensimycin 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, PLATENSIMYCIN 著者 Soisson, S.M, Parthasarathy, G. 登録日 2009-06-01 公開日 2010-02-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. Bioorg.Med.Chem.Lett., 19, 2009
4YUF	Crystal Structure of CorB 分子名称: CorB 著者 Zocher, G, Vilstrup, J, Stehle, T. 登録日 2015-03-18 公開日 2016-03-30 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural basis of head to head polyketide fusion by CorB. Chem Sci, 6, 2015
8PYX	Amide bond synthetase from Streptomyces hindustanus K492H mutant in complex with Adenosine 分子名称: ADENOSINE, Fatty-acyl-CoA synthase, SULFATE ION 著者 Tang, Q, Grogan, G. 登録日 2023-07-26 公開日 2024-02-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Broad Spectrum Enantioselective Amide Bond Synthetase from Streptoalloteichus hindustanus. Acs Catalysis, 14, 2024
4YUC	Crystal Structure of CorB derivatized with S-(2-acetamidoethyl) 4-methyl-3-oxohexanethioate 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CorB, SODIUM ION 著者 Zocher, G, Vilstrup, J, Stehle, T. 登録日 2015-03-18 公開日 2016-03-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Structural basis of head to head polyketide fusion by CorB. Chem Sci, 6, 2015
1ZGD	Chalcone Reductase Complexed With NADP+ at 1.7 Angstrom Resolution 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, chalcone reductase 著者 Bomati, E.K, Austin, M.B, Bowman, M.E, Dixon, R.A, Noel, J.P. 登録日 2005-04-21 公開日 2005-06-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis J.Biol.Chem., 280, 2005
8OTL	structure of InhA from Mycobacterium tuberculosis in complex with 5-(((4-(2-hydroxyphenoxy)benzyl)(octyl)amino)methyl)-2-phenoxyphenol 分子名称: 1,2-ETHANEDIOL, 5-[[octyl-[[4-(2-oxidanylphenoxy)phenyl]methyl]amino]methyl]-2-phenoxy-phenol, ACETATE ION, ... 著者 Tamhaev, R, Maveyraud, L, Chebaiki, M, Lherbet, C, Mourey, L. 登録日 2023-04-21 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.108 Å) 主引用文献 Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors. Bioorg.Chem., 143, 2023
1QR0	CRYSTAL STRUCTURE OF THE 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP-COENZYME A COMPLEX 分子名称: 4'-PHOSPHOPANTETHEINYL TRANSFERASE SFP, COENZYME A, MAGNESIUM ION 著者 Reuter, K, Mofid, R.M, Marahiel, A.M, Ficner, R. 登録日 1999-06-17 公開日 1999-12-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily. EMBO J., 18, 1999
5YZU	Crystal structure of KAS III from Acinetobacter baumannii 分子名称: 3-Oxoacyl-[acyl-carrier-(ACP)] synthase III C terminal family protein 著者 Lee, W.C, Jung, M, Lee, J, Kim, Y. 登録日 2017-12-15 公開日 2018-12-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.122 Å) 主引用文献 Crystal structure of a novel KAS III from Acinetobacter baumannii to be published
3WEW	Crystal structure of HtdX (Rv0241c) of Mycobacterium tuberculosis at 2.4 A resolution 分子名称: HtdX dehydratase, MAGNESIUM ION 著者 Biswas, R, Dutta, D, Das, A.K. 登録日 2013-07-16 公開日 2014-07-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a putative dehydratase HtdX of Mycobacterium tuberculosis To be Published
6QWU	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 5.5 with Mn2+ and CoA. 分子名称: COENZYME A, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-06 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
6QXQ	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 7 with Mn2+ and CoA. 分子名称: COENZYME A, MANGANESE (II) ION, Possible 4'-phosphopantetheinyl transferase 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-07 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
6QXR	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mn2+ and CoA. 分子名称: CALCIUM ION, COENZYME A, MANGANESE (II) ION, ... 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-07 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
8CN5	Pa.FabF-C164Q in complex with propan-2-yl 1~{H}-pyrazole-3-carboxylate 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Georgiou, C, Brenk, R. 登録日 2023-02-22 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
8CN8	apo Pseudomonas aeruginosa FabF C164A mutant 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2 著者 Georgiou, C, Brenk, R, Espeland, L.O. 登録日 2023-02-22 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
8CNG	Pa.FabF-C164Q in complex with ~{N}-cyclopentyl-3-methyl-1~{H}-pyrazole-5-carboxamide 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Georgiou, C, Brenk, R. 登録日 2023-02-22 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023
8CN2	Pa.FabF-C164Q in complex with N-isobutyl-1H-pyrazole-3-carboxamide 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ~{N}-(2-methylpropyl)-1~{H}-pyrazole-3-carboxamide 著者 Georgiou, C, Brenk, R. 登録日 2023-02-21 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023

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