1UHX
| Crystal structure of d(GCGAGAGC): the base-intercalated duplex | 分子名称: | 5'-D(*GP*(CBR)P*GP*AP*GP*AP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III), ... | 著者 | Kondo, J, Umeda, S.I, Fujita, K, Sunami, T, Takenaka, A. | 登録日 | 2003-07-13 | 公開日 | 2004-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray analyses of d(GCGAXAGC) containing G and T at X: the base-intercalated duplex is still stable even in point mutants at the fifth residue. J.Synchrotron Radiat., 11, 2004
|
|
1D28
| |
3WA5
| Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate immunity protein Tsi3 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Tse3-specific immunity protein, ... | 著者 | Ding, J, Wang, T, Liu, W, Wang, D.C. | 登録日 | 2013-04-26 | 公開日 | 2013-10-02 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Complex structure of type VI peptidoglycan muramidase effector and a cognate immunity protein. Acta Crystallogr.,Sect.D, 69, 2013
|
|
5QEI
| PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_PKTTA024495b | 分子名称: | 1-methyl-N-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | 著者 | Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. | 登録日 | 2018-08-30 | 公開日 | 2018-10-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.743 Å) | 主引用文献 | An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018
|
|
3EXS
| Crystal structure of KGPDC from Streptococcus mutans in complex with D-R5P | 分子名称: | RIBULOSE-5-PHOSPHATE, RmpD (Hexulose-6-phosphate synthase) | 著者 | Li, G.L, Liu, X, Wang, K.T, Li, L.F, Su, X.D. | 登録日 | 2008-10-17 | 公開日 | 2009-08-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Open-closed conformational change revealed by the crystal structures of 3-keto-L-gulonate 6-phosphate decarboxylase from Streptococcus mutans Biochem.Biophys.Res.Commun., 381, 2009
|
|
1YIT
| Crystal Structure Of Virginiamycin M and S Bound To The 50S Ribosomal Subunit Of Haloarcula Marismortui | 分子名称: | 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... | 著者 | Tu, D, Blaha, G, Moore, P.B, Steitz, T.A. | 登録日 | 2005-01-13 | 公開日 | 2005-04-26 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance. Cell(Cambridge,Mass.), 121, 2005
|
|
3SQM
| Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kim, Y, Chhor, G, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2011-07-05 | 公開日 | 2011-07-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Crystal Structure of Glycoside Hydrolase from Synechococcus Complexed with N-acetyl-D-glucosamine To be Published
|
|
1YIJ
| Crystal Structure Of Telithromycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui | 分子名称: | 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ... | 著者 | Tu, D, Blaha, G, Moore, P.B, Steitz, T.A. | 登録日 | 2005-01-12 | 公開日 | 2005-04-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance. Cell(Cambridge,Mass.), 121, 2005
|
|
2IQ7
| Crystal structure of the polygalacturonase from Colletotrichum lupini and its implications for the interaction with polygalacturonase-inhibiting proteins | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bonivento, D, Federici, L, Matteo, A.D. | 登録日 | 2006-10-13 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal structure of the endopolygalacturonase from the phytopathogenic fungus Colletotrichum lupini and its interaction with polygalacturonase-inhibiting proteins Proteins, 70, 2008
|
|
4IXF
| pcDHFR-269 F69N variant | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, N~6~-methyl-N~6~-[4-(propan-2-yl)phenyl]pyrido[2,3-d]pyrimidine-2,4,6-triamine | 著者 | Cody, V. | 登録日 | 2013-01-25 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design, Synthesis, and Molecular Modeling of Novel Pyrido[2,3-d]pyrimidine Analogues As Antifolates; Application of Buchwald-Hartwig Aminations of Heterocycles. J.Med.Chem., 56, 2013
|
|
2J8F
| |
1V7N
| Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | 分子名称: | Monoclonal TN1 Fab Heavy Chain, Monoclonal TN1 Fab Light Chain, Thrombopoietin | 著者 | Feese, M.D, Tamada, T, Kato, Y, Maeda, Y, Hirose, M, Matsukura, Y, Shigematsu, H, Kato, T, Miyazaki, H, Kuroki, R. | 登録日 | 2003-12-18 | 公開日 | 2004-03-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
4LOV
| Crystal structure of FimH in complex with Heptylmannoside | 分子名称: | GLYCEROL, Protein FimH, SODIUM ION, ... | 著者 | Garcia-Pino, A, Vanwetswinkel, S, van Nuland, N. | 登録日 | 2013-07-13 | 公開日 | 2014-02-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Study of the Structural and Dynamic Effects in the FimH Adhesin upon alpha-d-Heptyl Mannose Binding. J.Med.Chem., 57, 2014
|
|
4IFM
| |
3GJJ
| crystal structure of a DNA duplex containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one | 分子名称: | 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*(B7C)P*CP*GP*CP*G)-3' | 著者 | Takenaka, A, Juan, E.C.M, Shimizu, S, Haraguchi, T, Xiao, M, Kurose, T, Ohkubo, A, Sekine, M, Shibata, T, Millington, C.L, Williams, D.M. | 登録日 | 2009-03-09 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Insights into the stabilizing contributions of bicyclic cytosine analogues: crystal structures of DNA duplexes containing 7,8-dihydropyridol[2,3-d]pyrimidin-2-one To be Published
|
|
210D
| CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE | 分子名称: | DNA (5'-D(*CP*GP*TP*(1AP)P*CP*G)-3'), SPERMINE | 著者 | Parkinson, G.N, Arvantis, G.M, Lessinger, L, Ginell, S.L, Jones, R, Gaffney, B, Berman, H.M. | 登録日 | 1995-06-13 | 公開日 | 1996-03-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative. Biochemistry, 34, 1995
|
|
4IQ2
| P21 crystal form of FKBP12.6 | 分子名称: | MALONIC ACID, Peptidyl-prolyl cis-trans isomerase FKBP1B | 著者 | Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G. | 登録日 | 2013-01-10 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6. Acta Crystallogr.,Sect.D, 70, 2014
|
|
3DJF
| Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34 | 分子名称: | 2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | 著者 | Postigo, M.P, Pereira, H.M, Oliva, G, Andricopulo, A.D. | 登録日 | 2008-06-23 | 公開日 | 2009-06-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | 主引用文献 | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies. Bioorg.Med.Chem., 18, 2010
|
|
2NSX
| Structure of acid-beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCEROL, ... | 著者 | Lieberman, R.L, Petsko, G.A, Ringe, D. | 登録日 | 2006-11-06 | 公開日 | 2006-12-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease. Nat.Chem.Biol., 3, 2007
|
|
1C7E
| D95E HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D. | 登録日 | 2000-02-16 | 公開日 | 2000-08-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin Biochemistry, 41, 2002
|
|
1KZC
| Complex of MBP-C and high-affinity linear trimannose | 分子名称: | CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN C, ... | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-02-06 | 公開日 | 2002-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
|
|
1LJ7
| Crystal structure of calcium-depleted human C-reactive protein from perfectly twinned data | 分子名称: | C-reactive protein | 著者 | Ramadan, M.A, Shrive, A.K, Holden, D, Myles, D.A, Volanakis, J.E, DeLucas, L.J, Greenhough, T.J. | 登録日 | 2002-04-19 | 公開日 | 2002-06-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | The three-dimensional structure of calcium-depleted human C-reactive protein from perfectly twinned crystals. Acta Crystallogr.,Sect.D, 58, 2002
|
|
2NXH
| Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase. | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, PHOSPHATE ION, PHOSPHOENOLPYRUVATE | 著者 | Kona, F, Xu, X, Martin, P, Kuzmic, P, Gatti, D.L. | 登録日 | 2006-11-17 | 公開日 | 2007-04-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structural and Mechanistic Changes along an Engineered Path from Metallo to Nonmetallo 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthases. Biochemistry, 46, 2007
|
|
1XH2
| Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride and acarbose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, Alpha-amylase, ... | 著者 | Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D. | 登録日 | 2004-09-17 | 公開日 | 2005-05-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase PROTEIN SCI., 14, 2005
|
|
1KZB
| Complex of MBP-C and trimannosyl core | 分子名称: | CALCIUM ION, MANNOSE-BINDING PROTEIN C, alpha-D-mannopyranose | 著者 | Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I. | 登録日 | 2002-02-06 | 公開日 | 2002-07-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition. J.Biol.Chem., 277, 2002
|
|