4C4C
 
 | | Michaelis complex of Hypocrea jecorina CEL7A E217Q mutant with cellononaose spanning the active site | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ... | | 著者 | Haddad-Momeni, M, Sandgren, M, Stahlberg, J. | | 登録日 | 2013-09-05 | | 公開日 | 2014-01-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Mechanism of Cellulose Hydrolysis by a Two-Step, Retaining Cellobiohydrolase Elucidated by Structural and Transition Path Sampling Studies.
J.Am.Chem.Soc., 136, 2014
|
|
4BPQ
 | | Structure and substrate induced conformational changes of the secondary citrate-sodium symporter CitS revealed by electron crystallography | | 分子名称: | CITRATE:SODIUM SYMPORTER | | 著者 | Kebbel, F, Kurz, M, Arheit, M, Gruetter, M.G, Stahlberg, H. | | 登録日 | 2013-05-27 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6 Å) | | 主引用文献 | Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter Cits Revealed by Electron Crystallography.
Structure, 21, 2013
|
|
3OTO
 | | Crystal Structure of the 30S ribosomal subunit from a KsgA mutant of Thermus thermophilus (HB8) | | 分子名称: | 16S rRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Demirci, H, Murphy IV, F, Belardinelli, R, Kelley, A.C, Ramakrishnan, V, Gregory, S.T, Dahlberg, A.E, Jogl, G. | | 登録日 | 2010-09-13 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.69 Å) | | 主引用文献 | Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
Rna, 16, 2010
|
|
3OWI
 | |
3OXD
 | |
3P0K
 | |
4BWF
 | | Pex4p-Pex22p disulphide bond mutant | | 分子名称: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | | 著者 | Williams, C, van den Berg, M, Stanley, W.A, Wilmanns, M, Distel, B. | | 登録日 | 2013-07-01 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | A Disulphide Bond in the E2 Enzyme Pex4P Modulates Ubiquitin-Conjugating Activity
Sci.Rep., 3, 2013
|
|
4CB8
 | | Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha | | 分子名称: | BETA-CATENIN-LIKE PROTEIN 1, SULFATE ION | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Mutational Analysis Reveals that Ctnnbl1 Binds Nlss in a Manner Distinct from that of its Closest Armadillo-Relative, Karyopherin Alpha
FEBS Lett., 588, 2014
|
|
1SQA
 | | Substituted 2-Naphthamidine Inhibitors of Urokinase | | 分子名称: | 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE, SULFATE ION, Urokinase-type plasminogen activator | | 著者 | Wendt, M.D, Geyer, A, McClellan, W.J, Rockway, T.W, Weitzberg, M, Zhao, X, Stewart, K, Nienaber, V, Klinghofer, V, Giranda, V.L. | | 登録日 | 2004-03-18 | | 公開日 | 2004-04-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Interaction with the S1beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
|
|
1SLT
 | |
1SL0
 | | Ternary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template and an incoming nucleotide | | 分子名称: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', ... | | 著者 | Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T. | | 登録日 | 2004-03-05 | | 公開日 | 2004-07-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
|
|
1SN0
 | | Crystal Structure Of Sea Bream Transthyretin in complex with thyroxine At 1.9A Resolution | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, SULFATE ION, transthyretin | | 著者 | Eneqvist, T, Lundberg, E, Karlsson, A, Huang, S, Santos, C.R, Power, D.M, Sauer-Eriksson, A.E. | | 登録日 | 2004-03-10 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine.
J.Biol.Chem., 279, 2004
|
|
3PEH
 | | Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative | | 分子名称: | 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, Endoplasmin homolog, SULFATE ION | | 著者 | Wernimont, A.K, Tempel, W, Hutchinson, A, Weadge, J, Cossar, D, MacKenzie, F, Vedadi, M, Senisterra, G, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Wyatt, P.G, Fairlamb, A.H, MacKenzie, C, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2010-10-26 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative
To be Published
|
|
3PE6
 | |
1SAA
 | |
3PEU
 | | S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 H337R and IP6 | | 分子名称: | ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2020-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
|
|
3PEW
 | | S. cerevisiae Dbp5 L327V bound to RNA and ADP BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
|
|
3PEV
 | | S. cerevisiae Dbp5 L327V C-terminal domain bound to Gle1 and IP6 | | 分子名称: | ATP-dependent RNA helicase DBP5, GLYCEROL, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2020-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
|
|
3PEY
 | | S. cerevisiae Dbp5 bound to RNA and ADP BeF3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Montpetit, B, Thomsen, N.D, Helmke, K.J, Seeliger, M.A, Berger, J.M, Weis, K. | | 登録日 | 2010-10-27 | | 公開日 | 2011-03-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | | 主引用文献 | A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP(6) in mRNA export.
Nature, 472, 2011
|
|
3PFU
 | | N-terminal domain of Thiol:disulfide interchange protein DsbD in its reduced form | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thiol:disulfide interchange protein dsbD | | 著者 | Mavridou, D.A.I, Saridakis, E, Ferguson, S.J, Redfield, C. | | 登録日 | 2010-10-29 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Oxidation state-dependent protein-protein interactions in disulfide cascades
J.Biol.Chem., 286, 2011
|
|
3Q7U
 | | Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP | | 分子名称: | 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION | | 著者 | Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2011-01-05 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target
Proteins, 2011
|
|
3QEP
 | | RB69 DNA Polymerase (L561A/S565G/Y567A) Ternary Complex with dTTP Opposite Difluorotoluene Nucleoside | | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*GP*(DFT)P*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... | | 著者 | Xia, S, Konigsberg, W.H, Wang, J. | | 登録日 | 2011-01-20 | | 公開日 | 2011-08-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex.
J.Am.Chem.Soc., 133, 2011
|
|
3QIP
 | | Structure of HIV-1 reverse transcriptase in complex with an RNase H inhibitor and nevirapine | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 5,6-dihydroxy-2-[(2-phenyl-1H-indol-3-yl)methyl]pyrimidine-4-carboxylic acid, CHLORIDE ION, ... | | 著者 | Lansdon, E.B, Kirschberg, T.A. | | 登録日 | 2011-01-27 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.0926 Å) | | 主引用文献 | Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors.
Antimicrob.Agents Chemother., 55, 2011
|
|
3QB2
 | |
3QQY
 | |
