PDB: 225158 件ウェブページステータス検索Chemie searchBIRD

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4EDO	Crystal structure of far-red fluorescent protein eqFP650 分子名称: far-red fluorescent protein eqFP650 著者 Pletnev, S, Pletnev, V.Z, Pletneva, N.V. 登録日 2012-03-27 公開日 2012-09-05 最終更新日 2013-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for bathochromic shift of fluorescence in far-red fluorescent proteins eqFP650 and eqFP670. Acta Crystallogr.,Sect.D, 68, 2012
3OZK	Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4) 分子名称: 3,5,3',5'-TETRAIODO-L-THYRONINE, Transthyretin 著者 Lima, L.M.T.R, Palmieri, L.C, Foguel, D, Palhano, F.L. 登録日 2010-09-25 公開日 2011-08-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4) To be Published
3P2Y	Crystal structure of alanine dehydrogenase/pyridine nucleotide transhydrogenase from Mycobacterium smegmatis 分子名称: 1,2-ETHANEDIOL, Alanine dehydrogenase/pyridine nucleotide transhydrogenase, CALCIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-10-04 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2QJS	Stenotrophomonas maltophilia L1 metallo-beta-lactamase Asp-120 Asn mutant 分子名称: Metallo-beta-lactamase L1, ZINC ION 著者 Crisp, J, Conners, R, Spencer, J. 登録日 2007-07-09 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural Basis for the Role of Asp-120 in Metallo-beta-lactamases Biochemistry, 46, 2007
4EEV	Crystal structure of c-Met in complex with LY2801653 分子名称: Hepatocyte growth factor receptor, N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide 著者 Wang, Y, Stout, S.L. 登録日 2012-03-28 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models. Invest New Drugs, 31, 2013
3P03	Crystal structure of BetP-G153D with choline bound 分子名称: CHOLINE ION, Glycine betaine transporter BetP 著者 Perez, C, Ressl, S, Ziegler, Z. 登録日 2010-09-27 公開日 2011-03-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Substrate specificity and ion coupling in the Na(+)/betaine symporter BetP. Embo J., 30, 2011
2QK2	Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1 分子名称: LP04448p 著者 Slep, K.C, Vale, R.D. 登録日 2007-07-10 公開日 2007-10-02 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170, and EB1. Mol.Cell, 27, 2007
3P1B	Crystal structure of the native serine acetyltransferase 1 from Entamoeba histolytica 分子名称: SULFATE ION, Serine acetyltransferase 著者 Kumar, S, Gourinath, S. 登録日 2010-09-30 公開日 2011-02-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural and biochemical studies of serine acetyltransferase reveal why the parasite Entamoeba histolytica cannot form a cysteine synthase complex J.Biol.Chem., 286, 2011
2GWH	Human Sulfotranferase SULT1C2 in complex with PAP and pentachlorophenol 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, PENTACHLOROPHENOL, Sulfotransferase 1C2, ... 著者 Tempel, W, Pan, P.W, Dombrovski, L, Allali-Hassani, A, Vedadi, M, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2006-05-04 公開日 2006-05-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and chemical profiling of the human cytosolic sulfotransferases. Plos Biol., 5, 2007
2QKH	Crystal structure of the extracellular domain of human GIP receptor in complex with the hormone GIP 分子名称: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, D(-)-TARTARIC ACID, Glucose-dependent insulinotropic polypeptide, ... 著者 Parthier, C, Kleinschmidt, M, Neumann, P, Rudolph, R, Manhart, S, Schlenzig, D, Fanghanel, J, Rahfeld, J.-U, Demuth, H.-U, Stubbs, M.T. 登録日 2007-07-11 公開日 2007-08-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor Proc.Natl.Acad.Sci.Usa, 104, 2007
2QEH	Crystal Structure of Anopheles gambiae D7r4-serotonin complex 分子名称: D7R4 Protein, SEROTONIN 著者 Andersen, J.F, Mans, B.J, Calvo, E, Ribeiro, J.M. 登録日 2007-06-25 公開日 2007-10-09 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae J.Biol.Chem., 282, 2007
2QLQ	Crystal structure of SRC kinase domain with covalent inhibitor RL3 分子名称: (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, Proto-oncogene tyrosine-protein kinase Src 著者 Michalczyk, A, Rode, H.B, Gruetter, C, Rauh, D. 登録日 2007-07-13 公開日 2008-03-11 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg.Med.Chem., 16, 2008
3P3C	Crystal Structure of the Aquifex aeolicus LpxC/LPC-009 complex 分子名称: N-[(1S,2R)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide, PHOSPHATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... 著者 Lee, C.-J, Zhou, P. 登録日 2010-10-04 公開日 2011-01-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem.Biol., 18, 2011
2QF4	High resolution structure of the major periplasmic domain from the cell shape-determining filament MreC (orthorhombic form) 分子名称: 1,2-ETHANEDIOL, Cell shape determining protein MreC, SULFATE ION 著者 Lovering, A.L, Strynadka, N.C.J. 登録日 2007-06-26 公開日 2007-08-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 High-resolution Structure of the Major Periplasmic Domain from the Cell Shape-determining Filament MreC. J.Mol.Biol., 372, 2007
2QFC	Crystal Structure of Bacillus thuringiensis PlcR complexed with PapR 分子名称: C-terminus pentapeptide from PapR protein, DI(HYDROXYETHYL)ETHER, PlcR protein 著者 Declerck, N, Chaix, D, Rugani, N, Hoh, F, Arold, S.T. 登録日 2007-06-27 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria Proc.Natl.Acad.Sci.Usa, 104, 2007
2HB4	Structure of HIV Protease NL4-3 in an Unliganded State 分子名称: MAGNESIUM ION, Protease, R-1,2-PROPANEDIOL 著者 Heaslet, H, Tam, K, Elder, J.H, Stout, C.D. 登録日 2006-06-13 公開日 2007-06-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63, 2007
3P8J	Y351S mutant of pentaerythritol tetranitrate reductase containing a bound acetate molecule 分子名称: ACETATE ION, FLAVIN MONONUCLEOTIDE, Pentaerythritol tetranitrate reductase 著者 Toogood, H.S, Scrutton, N.S. 登録日 2010-10-14 公開日 2011-04-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with a,b-unsaturated nitroolefins Catalysis Science and Technology, 2011
4EFZ	Crystal Structure of a hypothetical metallo-beta-lactamase from Burkholderia pseudomallei 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 SSGCID, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-03-30 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of a hypothetical metallo-beta-lactamase from Burkholderia pseudomallei TO BE PUBLISHED
2H0B	Crystal Structure of the second LNS/LG domain from Neurexin 1 alpha 分子名称: CALCIUM ION, GLYCEROL, Neurexin-1-alpha 著者 Sheckler, L.R, Henry, L, Sugita, S, Sudhof, T.C, Rudenko, G. 登録日 2006-05-14 公開日 2006-06-20 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the Second LNS/LG Domain from Neurexin 1{alpha}: Ca2+ binding and the effects of alternative splicing J.Biol.Chem., 281, 2006
3P4N	Crystal Structure of H2-Kb in complex with the NP205-PV epitope YTVKFPNM, an 8-mer peptide from PV 分子名称: ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... 著者 Gras, S, Guillonneau, C, Rossjohn, J. 登録日 2010-10-06 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of H2-Kb in complex with the NP205-PV epitope YTVKFPNM, an 8-mer peptide from PV To be Published
2QFV	Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+) 分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Peng, Y.J, Ding, J.P. 登録日 2007-06-28 公開日 2008-07-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17, 2008
3P56	The structure of the human RNase H2 complex defines key interaction interfaces relevant to enzyme function and human disease 分子名称: Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C 著者 Bubeck, D, Graham, S.C, Jones, E.Y. 登録日 2010-10-08 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4.06 Å) 主引用文献 The Structure of the Human RNase H2 Complex Defines Key Interaction Interfaces Relevant to Enzyme Function and Human Disease. J.Biol.Chem., 286, 2011
2QGH	Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori complexed with L-lysine 分子名称: Diaminopimelate decarboxylase, GLYCEROL, LYSINE, ... 著者 Hu, T, Wu, D, Jiang, H, Shen, X. 登録日 2007-06-28 公開日 2008-05-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of diaminopimelate decarboxylase from Helicobacter pylori complexed with L-lysine TO BE PUBLISHED
2QOJ	Coevolution of a homing endonuclease and its host target sequence 分子名称: I-AniI DNA target seq1, I-AniI DNA target seq2, LAGLIDADG endonuclease, ... 著者 Scalley-Kim, M, McConnell Smith, A, Stoddard, B.L. 登録日 2007-07-20 公開日 2008-11-11 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Coevolution of a homing endonuclease and its host target sequence. J.Mol.Biol., 372, 2007
2QGW	Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with a Chloro-Indazole Compound 分子名称: 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL, Estrogen receptor, Nuclear receptor coactivator 2 著者 Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L. 登録日 2007-06-29 公開日 2008-03-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008

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