PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

---

6G2I	Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution 分子名称: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein 著者 Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. 登録日 2018-03-23 公開日 2018-06-13 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis for regulation of human acetyl-CoA carboxylase. Nature, 558, 2018
6FUY	Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066) 分子名称: CALCIUM ION, Vinculin 著者 Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B. 登録日 2018-02-28 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational states during vinculin unlocking differentially regulate focal adhesion properties. Sci Rep, 8, 2018
6FXR	Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Cocrystal with Fe2+, Mn2+, UDP-Gal 分子名称: 2-OXOGLUTARIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scietti, L, Chiapparino, A, De Giorgi, F, Fumagalli, M, Khoriauli, L, Nergadze, S, Basu, S, Olieric, V, Banushi, B, Giulotto, E, Gissen, P, Forneris, F. 登録日 2018-03-09 公開日 2018-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3. Nat Commun, 9, 2018
3OG9	Structure of YahD with Malic acid 分子名称: D-MALATE, protein yahD a copper inducible hydrolase 著者 Martinez Font, J, Mancini, S, Tauberger, E, Moniot, S. 登録日 2010-08-16 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Regulation and structure of YahD, a copper inducible alpha/beta hydrolase of Lactococcus lactis IL1403 Fems Microbiol.Lett., 314, 2011
3OGI	Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP complex (Rv2346c-Rv2347c) 分子名称: Putative ESAT-6-like protein 6, Putative ESAT-6-like protein 7 著者 Arbing, M.A, Chan, S, Zhou, T.T, Ahn, C, Harris, L, Kuo, E, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) 登録日 2010-08-16 公開日 2010-08-25 最終更新日 2014-05-21 実験手法 X-RAY DIFFRACTION (2.549 Å) 主引用文献 Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions. Plos One, 8, 2013
6GSB	Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical 分子名称: MANGANESE (II) ION, Superoxide dismutase 著者 Rashid, G.M, Zhang, X, Wilkinson, R.C, Fulop, V, Cottyn, B, Baumberger, S, Bugg, D.H. 登録日 2018-06-13 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Sphingobacterium sp. T2 Manganese Superoxide Dismutase Catalyzes the Oxidative Demethylation of Polymeric Lignin via Generation of Hydroxyl Radical. ACS Chem. Biol., 13, 2018
7LQ7	Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA1-16 heavy chain, COVA1-16 light chain, ... 著者 Yuan, M, Zhu, X, Wilson, I.A. 登録日 2021-02-13 公開日 2021-09-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern. Sci Transl Med, 13, 2021
3OGU	DNA Polymerase beta mutant 5P20 complexed with 6bp of DNA 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*AP*TP*CP*TP*G)-3', 5'-D(P*CP*AP*GP*AP*TP*G)-3', ... 著者 Marx, A, Diederichs, K, Bergen, K. 登録日 2010-08-17 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.845 Å) 主引用文献 Human DNA polymerase beta mutations allowing efficient abasic site bypass. J.Biol.Chem., 286, 2011
4AL7	Crystal structure of the Csy4-minimal crRNA complex 分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*AP*G)-3', CSY4 ENDORIBONUCLEASE 著者 Haurwitz, R.E, Sternberg, S.H, Doudna, J.A. 登録日 2012-03-02 公開日 2012-06-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Csy4 Relies on an Unusual Catalytic Dyad to Position and Cleave Crispr RNA. Embo J., 31, 2012
4AHE	K17I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: ANGIOGENIN, L(+)-TARTARIC ACID 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
4AHH	R31K - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: ANGIOGENIN, L(+)-TARTARIC ACID 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
6GQM	Crystal structure of human c-KIT kinase domain in complex with a small molecule inhibitor, AZD3229 分子名称: CHLORIDE ION, Mast/stem cell growth factor receptor Kit, ~{N}-[4-[[5-fluoranyl-7-(2-methoxyethoxy)quinazolin-4-yl]amino]phenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide 著者 Schimpl, M, Hardy, C.J, Ogg, D.J, Overman, R.C, Packer, M.J, Kettle, J.G, Anjum, R, Barry, E, Bhavsar, D, Brown, C, Campbell, A, Goldberg, K, Grondine, M, Guichard, S, Hunt, T, Jones, O, Li, X, Moleva, O, Pearson, S, Shao, W, Smith, A, Smith, J, Stead, D, Stokes, S, Tucker, M, Ye, Y. 登録日 2018-06-07 公開日 2018-09-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J. Med. Chem., 61, 2018
4AKE	ADENYLATE KINASE 分子名称: ADENYLATE KINASE 著者 Schlauderer, G.J, Schulz, G.E. 登録日 1995-12-29 公開日 1996-06-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Adenylate kinase motions during catalysis: an energetic counterweight balancing substrate binding. Structure, 4, 1996
1RW1	YFFB (PA3664) PROTEIN 分子名称: ISOPROPYL ALCOHOL, conserved hypothetical protein yffB 著者 Teplyakov, A, Pullalarevu, S, Obmolova, G, Doseeva, V, Galkin, A, Herzberg, O, Dauter, M, Dauter, Z, Gilliland, G.L, Structure 2 Function Project (S2F) 登録日 2003-12-15 公開日 2004-11-02 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function. Bmc Struct.Biol., 4, 2004
4A4Q	Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors 分子名称: PROTEASE, methyl [(2S)-1-{2-(2-{(3R,4S)-3-benzyl-4-hydroxy-1-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-2-oxopyrrolidin-3-yl}ethyl)-2-[4-(pyridin-4-yl)benzyl]hydrazinyl}-3,3-dimethyl-1-oxobutan-2-yl]carbamate 著者 Wu, X, Ohrngren, P, Joshi, A.A, Trejos, A, Persson, M, Arvela, R.K, Wallberg, H, Vrang, L, Rosenquist, A, Samuelsson, B, Unge, J, Larhed, M. 登録日 2011-10-19 公開日 2012-11-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthesis, X-Ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors. J.Med.Chem., 55, 2012
4A6C	Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors 分子名称: METHYL ((S)-1-(2-(3-((3S,4S)-3-BENZYL-4-HYDROXY-1-((1S,2R)-2-HYDROXY-2,3-DIHYDRO-1H-INDEN-1-YL)-2-OXOPYRROLIDIN-3-YL)PROPYL)-2-(4-(PYRIDIN-4-YL)BENZYL)HYDRAZINYL)-3,3-DIMETHYL-1-OXOBUTAN-2-YL)CARBAMATE, POL PROTEIN 著者 Wu, X, Ohrngren, P, Joshi, A.A, Trejos, A, Persson, M, Unge, J, Arvela, R.K, Wallberg, H, Vrang, L, Rosenquist, A, Samuelsson, B.B, Unge, J, Larhed, M. 登録日 2011-11-01 公開日 2012-05-09 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Synthesis, X-Ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease Inhibitors. J.Med.Chem., 55, 2012
3ZMP	Src-derived peptide inhibitor complex of PTP1B 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 著者 Temmerman, K, Pogenberg, V, Meyer, C, Koehn, M, Wilmanns, M. 登録日 2013-02-12 公開日 2014-01-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.619 Å) 主引用文献 Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells. Acs Chem.Biol., 9, 2014
3ZOH	Crystal structure of FMN-binding protein (YP_005476) from Thermus thermophilus with bound 1-Cyclohex-2-enone 分子名称: FLAVIN MONONUCLEOTIDE, FLAVOREDOXIN, cyclohex-2-en-1-one 著者 Pavkov-Keller, T, Steinkellner, G, Gruber, C.C, Steiner, K, Winkler, C, Schwamberger, O, Schwab, H, Faber, K, Gruber, K. 登録日 2013-02-21 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations. Nat.Commun., 5, 2014
1RGS	REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP DEPENDENT PROTEIN KINASE 著者 Su, Y, Dostmann, W.R.G, Herberg, F.W, Durick, K, Xuong, N.-H, Ten Eyck, L, Taylor, S.S, Varughese, K.I. 登録日 1995-06-21 公開日 1996-12-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains. Science, 269, 1995
3ZBU	Ferredoxin-NADP Reductase Mutant with SER 80 Replaced by ALA (S80A) 分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Martinez-Julvez, M, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M. 登録日 2012-11-13 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency. Biochim.Biophys.Acta, 1837, 2013
3ZBT	Ferredoxin-NADP Reductase Mutant with SER 59 Replaced by ALA (S59A) 分子名称: FERREDOXIN-NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Martinez-Julvez, M, Herguedas, B, Sanchez-Azqueta, A, Hervas, M, Navarro, J.A, Medina, M. 登録日 2012-11-13 公開日 2013-11-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 A Hydrogen Bond Network in the Active Site of Anabaena Ferredoxin-Nadp(+) Reductase Modulates its Catalytic Efficiency. Biochim.Biophys.Acta, 1837, 2013
3ZOC	Crystal structure of FMN-binding protein (NP_142786.1) from Pyrococcus horikoshii with bound p-hydroxybenzaldehyde 分子名称: FLAVIN MONONUCLEOTIDE, FMN-BINDING PROTEIN, P-HYDROXYBENZALDEHYDE 著者 Pavkov-Keller, T, Steinkellner, G, Gruber, C.C, Steiner, K, Winkler, C, Schwamberger, O, Schwab, H, Faber, K, Gruber, K. 登録日 2013-02-21 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification of Promiscuous Ene-Reductase Activity by Mining Structural Databases Using Active Site Constellations. Nat.Commun., 5, 2014
3PGR	Asp348Arg mutant of EcFadL 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Long-chain fatty acid transport protein 著者 Lepore, B.W, van den Berg, B, Indic, M, Hearn, E, Patel, D, Pham, H. 登録日 2010-11-02 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 From the Cover: Ligand-gated diffusion across the bacterial outer membrane. Proc.Natl.Acad.Sci.USA, 108, 2011
3PGU	Phe3Glu mutant of EcFadL 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Long-chain fatty acid transport protein, NICKEL (II) ION, ... 著者 Lepore, B.W, Indic, M, Pham, H, Hearn, E, Patel, D, van den Berg, B. 登録日 2010-11-02 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 From the Cover: Ligand-gated diffusion across the bacterial outer membrane. Proc.Natl.Acad.Sci.USA, 108, 2011
6FM0	Deoxyguanylosuccinate synthase (DgsS) and ATP structure at 1.7 Angstrom resolution 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase 著者 Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. 登録日 2018-01-29 公開日 2019-06-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021

<363364365366367368369370371372373374375376377378>