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4IUJ
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BU of 4iuj by Molmil
Structure of Polymerase acid protein (PA) from Influenzavirus A Influenza A virus A, WILSON-SMITH/1933 (H1N1)
分子名称: Polymerase acidic protein
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-01-21
公開日2013-02-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Sci Rep, 4, 2014
3RJR
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BU of 3rjr by Molmil
Crystal Structure of pro-TGF beta 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Transforming growth factor beta-1
著者Zhu, J.H, Shi, M.L, Springer, T.A.
登録日2011-04-15
公開日2011-06-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Latent TGF-Beta structure and activation
Nature, 474, 2011
3DC8
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BU of 3dc8 by Molmil
Crystal structure of dihydropyrimidinase from Sinorhizobium meliloti
分子名称: ACETATE ION, Dihydropyrimidinase, GLYCEROL, ...
著者Gavira, J.A, Martinez-Rodriguez, S.
登録日2008-06-03
公開日2009-04-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of dihydropyrimidinase from Sinorhizobium meliloti CECT4114: new features in an amidohydrolase family member
J.Struct.Biol., 169, 2010
3DYV
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BU of 3dyv by Molmil
Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism
分子名称: CHLORIDE ION, Esterase D
著者Bennett, M.D, Delabre, M.-L, Holland, R, Norris, G.E.
登録日2008-07-28
公開日2009-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Snapshots of esterase D from lactobacillus rhamnosus: Insights into a rotation driven catalytic mechanism
To be Published
3DZ8
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BU of 3dz8 by Molmil
Crystal structure of human Rab3B GTPase bound with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-3B, UNKNOWN ATOM OR ION
著者Shen, Y, Tong, Y, Sukumar, D, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-07-29
公開日2008-08-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Rab3B GTPase bound with GDP
To be Published
2PL7
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BU of 2pl7 by Molmil
Orhorhombic crystal structure of hydrophobin HFBII in the presence of a detergent
分子名称: Hydrophobin-2, SULFATE ION, heptyl 1-thio-beta-D-glucopyranoside
著者Kallio, J.M, Rouvinen, J.P.
登録日2007-04-19
公開日2007-07-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal Structures of Hydrophobin HFBII in the Presence of Detergent Implicate the Formation of Fibrils and Monolayer Films.
J.Biol.Chem., 282, 2007
3R77
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BU of 3r77 by Molmil
Crystal structure of the D38A mutant of isochorismatase PhzD from Pseudomonas fluorescens 2-79 in complex with 2-amino-2-desoxyisochorismate ADIC
分子名称: (5S,6S)-6-amino-5-[(1-carboxyethenyl)oxy]cyclohexa-1,3-diene-1-carboxylic acid, CHLORIDE ION, Probable isochorismatase
著者Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W.
登録日2011-03-22
公開日2011-03-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE.
J.Biol.Chem., 286, 2011
3D97
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Crystal Structure of the R132K:R111L:L121E Mutant of Apo-Cellular Retinoic Acid Binding Protein Type II At 1.50 Angstroms Resolution
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular retinoic acid-binding protein 2, SODIUM ION
著者Vaezeslami, S, Geiger, J.H.
登録日2008-05-26
公開日2008-07-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Determining Crystal Structures of Proteins and Protein Complexes by X-Ray Crystallography: X-Ray Crystallographic Studies of the Mutants of Cellular Retinoic Acid Binding Protein Type II Toward Designing a Mimic of Rhodopsin.
Thesis
4H3Z
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BU of 4h3z by Molmil
Crystal structure of a symmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in both half-sites
分子名称: CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(1)-)-methyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-09-14
公開日2012-10-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
3DAX
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BU of 3dax by Molmil
Crystal structure of human CYP7A1
分子名称: Cytochrome P450 7A1, PROTOPORPHYRIN IX CONTAINING FE, UNKNOWN ATOM OR ION
著者Strushkevich, N.V, Tempel, W, Dombrovski, L, Dong, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-08-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of human CYP7A1
To be Published
4H5I
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BU of 4h5i by Molmil
Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P1 form)
分子名称: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
著者McMahon, C, Jeffrey, P.D, Hughson, F.M.
登録日2012-09-18
公開日2012-11-07
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012
2PRB
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BU of 2prb by Molmil
crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A
分子名称: Aminoglycoside 6-N-acetyltransferase type Ib11, COENZYME A
著者Maurice, F, Broutin, I, Podglajen, I, Benas, P, Collatz, E, Dardel, F.
登録日2007-05-04
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance.
Embo Rep., 9, 2008
3R9Q
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BU of 3r9q by Molmil
Structure of a probable enoyl-coa hydratase/isomerase from Mycobacterium abscessus ATCC 19977 / DSM 44196
分子名称: CHLORIDE ION, GLYCEROL, enoyl-coA hydratase/isomerase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-25
公開日2011-04-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4ECK
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BU of 4eck by Molmil
Crystal Structure of the Toxoplasma gondii TS-DHFR
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Sharma, H, Anderson, K.S.
登録日2012-03-26
公開日2013-10-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.516 Å)
主引用文献First Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase-Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate Channeling.
Biochemistry, 52, 2013
4EDB
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BU of 4edb by Molmil
Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses
分子名称: Hemagglutinin
著者Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I.
登録日2012-03-27
公開日2013-05-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Insight into structural diversity of influenza virus haemagglutinin
J.Gen.Virol., 94, 2013
4H5P
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BU of 4h5p by Molmil
Crystal Structure of Rift Valley Fever Virus Nucleocapsid Protein Tetramer Bound to Single-stranded RNA
分子名称: 28-mer poly(U) RNA, Nucleocapsid protein
著者Raymond, D.D, Smith, J.L.
登録日2012-09-18
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Phleboviruses encapsidate their genomes by sequestering RNA bases.
Proc.Natl.Acad.Sci.USA, 109, 2012
3DJH
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BU of 3djh by Molmil
Macrophage Migration Inhibitory Factor (MIF) at 1.25 A Resolution
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
著者Crichlow, G.V, Lolis, E.
登録日2008-06-23
公開日2008-12-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Biochemistry, 48, 2009
4DYA
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BU of 4dya by Molmil
Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-885986 Ligand Bound
分子名称: N-[4-chloranyl-5-[4-[[3-(2-methoxyphenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]piperazin-1-yl]-2-nitro-phenyl]furan-2-carboxamide, Nucleocapsid protein
著者Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R.
登録日2012-02-28
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献To be determined
To be Published
3RPX
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BU of 3rpx by Molmil
Crystal structure of complement component 1, q subcomponent binding protein, C1QBP
分子名称: Complement component 1 Q subcomponent-binding protein, UNKNOWN ATOM OR ION
著者Tempel, W, Tong, Y, Crombet, L, Shen, Y, Guan, X, Nedyalkova, L, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
登録日2011-04-27
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of complement component 1, q subcomponent binding protein, C1QBP
to be published
4H7P
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Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin
分子名称: Malate dehydrogenase, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-09-20
公開日2012-10-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of a putative Cytosolic malate dehydrogenase from Leishmania major Friedlin
To be Published
4DYP
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BU of 4dyp by Molmil
Crystal Structure of WSN/A Influenza Nucleoprotein with BMS-831780 Ligand Bound
分子名称: Nucleocapsid protein, [4-(5-bromanyl-3-methyl-pyridin-2-yl)piperazin-1-yl]-[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]methanone
著者Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R.
登録日2012-02-29
公開日2013-03-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献To be determined
To be Published
4DI2
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BU of 4di2 by Molmil
Crystal structure of BACE1 in complex with hydroxyethylamine inhibitor 37
分子名称: (2R)-N-{(2S,3R)-4-{[(4'S)-6'-(2,2-dimethylpropyl)-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl]amino}-3-hydroxy-1-[3-(1,3-thiazol-2-yl)phenyl]butan-2-yl}-2-methoxypropanamide, Beta-secretase 1, GLYCEROL
著者Whittington, D.A, Long, A.M.
登録日2012-01-30
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Design and synthesis of potent, orally efficacious hydroxyethylamine derived beta-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors.
J.Med.Chem., 55, 2012
3RCY
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BU of 3rcy by Molmil
CRYSTAL STRUCTURE OF Mandelate racemase/muconate lactonizing enzyme-like protein from Roseovarius sp. TM1035
分子名称: GLYCEROL, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme-like protein, ...
著者Malashkevich, V.N, Toro, R, Seidel, R, Garrett, S, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2011-03-31
公開日2011-05-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献CRYSTAL STRUCTURE OF Mandelate racemase/muconate lactonizing enzyme-like protein from Roseovarius sp. TM1035
To be Published
4H8X
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Radiation damage study of lysozyme - 0.07 MGy
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C
著者Sutton, K.A, Snell, E.H.
登録日2012-09-24
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1998 Å)
主引用文献Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies.
Acta Crystallogr.,Sect.D, 69, 2013
3RR6
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Structure of a putative uncharacterized protein from Mycobacterium abscessus ATCC 19977 / DSM 44196
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Putative uncharacterized protein, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-04-29
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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