PDB: 231319 件ウェブページステータス検索Chemie searchBIRD

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7AHT	Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 7.5 分子名称: K(+)/H(+) antiporter subunit KhtT 著者 Cereija, T.B, Morais-Cabral, J.H. 登録日 2020-09-25 公開日 2021-03-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 c-di-AMP, a likely master regulator of bacterial K + homeostasis machinery, activates a K + exporter. Proc.Natl.Acad.Sci.USA, 118, 2021
6GSC	Sphingobacterium sp. T2 manganese superoxide dismutase catalyses the oxidative demethylation of polymeric lignin via generation of hydroxyl radical 分子名称: MANGANESE (II) ION, Superoxide dismutase 著者 Rashid, G.M.M, Zhang, X, Wilkinson, R.C, Fulop, V, Cottyn, B, Baumberger, S, Bugg, T.D.H. 登録日 2018-06-13 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Sphingobacterium sp. T2 Manganese Superoxide Dismutase Catalyzes the Oxidative Demethylation of Polymeric Lignin via Generation of Hydroxyl Radical. ACS Chem. Biol., 13, 2018
4YM3	Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lactose 分子名称: Galectin-4, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Bum-Erdene, K, Blanchard, H. 登録日 2015-03-06 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens. Febs J., 282, 2015
9IIP	Fucokinase part of FKP with beta-L-fucose 1-phosphate 分子名称: 6-deoxy-1-O-phosphono-beta-L-galactopyranose, L-fucokinase/L-fucose-1-P guanylyltransferase 著者 Ko, T.P, Lin, S.W, Hsu, M.F, Lin, C.H. 登録日 2024-06-21 公開日 2025-03-05 最終更新日 2025-04-09 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural insight into the catalytic mechanism of the bifunctional enzyme l-fucokinase/GDP-fucose pyrophosphorylase. J.Biol.Chem., 301, 2025
7T5H	Structure of rabies virus phosphoprotein C-terminal domain, wild type 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Phosphoprotein, ... 著者 Zhan, J, Metcalfe, R.D, Gooley, P.R, Griffin, M.D.W. 登録日 2021-12-12 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein. J.Virol., 96, 2022
7LXL	Crystal structure of human CYP3A4 bound to the testosterone dimer 分子名称: 17alpha-hydroxy-7alpha-[(2Z)-4-(17beta-hydroxy-3-oxo-8alpha-androst-4-en-7beta-yl)but-2-en-1-yl]-8alpha,10alpha,13alpha,14beta-androst-4-en-3-one, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F. 登録日 2021-03-04 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Innovative C 2 -symmetric testosterone and androstenedione dimers: Design, synthesis, biological evaluation on prostate cancer cell lines and binding study to recombinant CYP3A4. Eur.J.Med.Chem., 220, 2021
5IHP	Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ADP and Magnesium 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cobyrinic Acid a,c-diamide synthase, MAGNESIUM ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-29 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium TO BE PUBLISHED
9DIG	Rous sarcoma virus frameshifting pseudoknot RNA EM straight dimer 分子名称: MAGNESIUM ION, POTASSIUM ION, frameshifting pseudoknot RNA 著者 Jones, C.P, Ferre-D'Amare, A.R. 登録日 2024-09-05 公開日 2025-04-09 最終更新日 2025-04-16 実験手法 ELECTRON MICROSCOPY (3.22 Å) 主引用文献 Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element. Proc.Natl.Acad.Sci.USA, 122, 2025
6SD4	Structure of the RBM3/collar region of the Salmonella flagella MS-ring protein FliF with 34-fold symmetry applied 分子名称: Flagellar M-ring protein 著者 Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. 登録日 2019-07-26 公開日 2020-03-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation. Nat Microbiol, 5, 2020
5MGX	The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP8, yeast HSP90 C-terminus 著者 Roe, S.M, Blundell, K.L, Prodromou, C. 登録日 2016-11-22 公開日 2017-03-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90. PLoS ONE, 12, 2017
6FKV	Structure and function of aldehyde dehydrogenase from Thermus thermophilus: An enzyme with an evolutionarily-distinct C-terminal arm (Recombinant protein with shortened C-terminal, ADH508) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aldehyde dehydrogenase, CHLORIDE ION, ... 著者 Hayes, K.A, Noor, M.R, Djeghader, A, Soulimane, T. 登録日 2018-01-24 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension. Sci Rep, 8, 2018
6ZXK	Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement 分子名称: Lethal factor, Protective antigen 著者 Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S. 登録日 2020-07-29 公開日 2020-09-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. Plos Pathog., 16, 2020
8TDQ	SFX-XFEL structure of CYP121 cocrystallized with substrate cYY 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Nguyen, R.C, Dasgupta, M, Bhowmick, A, Kern, J.F, Liu, A. 登録日 2023-07-04 公開日 2023-11-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 In Situ Structural Observation of a Substrate- and Peroxide-Bound High-Spin Ferric-Hydroperoxo Intermediate in the P450 Enzyme CYP121. J.Am.Chem.Soc., 145, 2023
8R4C	LRR domain of Roco protein from C. tepidum bound to the activating Nanobody NbRoco2 分子名称: NbRoco2, Rab family protein 著者 Galicia, C, Versees, W. 登録日 2023-11-13 公開日 2024-05-01 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Structural insights into the GTP-driven monomerization and activation of a bacterial LRRK2 homolog using allosteric nanobodies. Elife, 13, 2024
5XQH	Crystal structure of truncated human Rogdi 分子名称: Protein rogdi homolog 著者 Lee, H, Lee, C. 登録日 2017-06-07 公開日 2017-07-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 The crystal structure of human Rogdi provides insight into the causes of Kohlschutter-Tonz Syndrome Sci Rep, 7, 2017
5XHB	Crystal structure of the full length of NisI in a lipid free form, the nisin immunity protein, from Lactococcus lactis 分子名称: Nisin immunity protein, SULFATE ION 著者 Ha, S.C. 登録日 2017-04-20 公開日 2017-12-27 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of NisI in a Lipid-Free Form, the Nisin Immunity Protein, from Lactococcus lactis Antimicrob. Agents Chemother., 62, 2018
8TDP	Time-resolved SFX-XFEL crystal structure of CYP121 bound with cYY reacted with peracetic acid for 200 milliseconds 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, HYDROGEN PEROXIDE, Mycocyclosin synthase, ... 著者 Nguyen, R.C, Dasgupta, M, Bhowmick, A, Kern, J.F, Liu, A. 登録日 2023-07-04 公開日 2023-11-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 In Situ Structural Observation of a Substrate- and Peroxide-Bound High-Spin Ferric-Hydroperoxo Intermediate in the P450 Enzyme CYP121. J.Am.Chem.Soc., 145, 2023
6NT9	Cryo-EM structure of the complex between human TBK1 and chicken STING 分子名称: Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein 著者 Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. 登録日 2019-01-28 公開日 2019-03-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of STING binding with and phosphorylation by TBK1. Nature, 567, 2019
8R4B	Roco protein from C. tepidum in the GTP state bound to the activating Nanobodies NbRoco1 and NbRoco2 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, NbRoco1, NbRoco2, ... 著者 Galicia, C, Versees, W. 登録日 2023-11-13 公開日 2024-05-01 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Structural insights into the GTP-driven monomerization and activation of a bacterial LRRK2 homolog using allosteric nanobodies. Elife, 13, 2024
6NKS	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with beta-gamma CHF analog of dGTP 分子名称: 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKW	Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with beta-gamma-methylene dGTP 分子名称: 2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
2WH9	Solution structure of GxTX-1E 分子名称: GUANGXITOXIN-1EGXTX-1E 著者 Lee, S.K, Jung, H.H, Lee, J.Y, Lee, C.W, Kim, J.I. 登録日 2009-05-02 公開日 2010-05-26 最終更新日 2024-11-06 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels. Biochemistry, 49, 2010
7M6M	Full length alpha1 Glycine receptor in presence of 32uM Tetrahydrocannabinol 分子名称: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1 著者 Kumar, A, Chakrapani, S. 登録日 2021-03-26 公開日 2022-08-03 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs. Nat Commun, 13, 2022
6VQJ	Mammalian V-ATPase from rat brain collar and peripheral stalks rotational state 2 (from focused refinement) 分子名称: V-type proton ATPase 116 kDa subunit a isoform 1, V-type proton ATPase subunit C 1, V-type proton ATPase subunit E 1, ... 著者 Abbas, Y.M, Rubinstein, J.L. 登録日 2020-02-05 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structure of V-ATPase from the mammalian brain. Science, 367, 2020
7M6Q	Full length alpha1 Glycine receptor in presence of 1mM Glycine and 32uM Tetrahydrocannabinol State 1 分子名称: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... 著者 Kumar, A, Chakrapani, S. 登録日 2021-03-26 公開日 2022-08-03 最終更新日 2025-05-28 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs. Nat Commun, 13, 2022

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