6X0S
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6X0T
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![BU of 6x0t by Molmil](/molmil-images/mine/6x0t) | Structure of human plasma factor XIIa in complex with (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 8h) | 分子名称: | (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide, Coagulation factor XII, SULFATE ION | 著者 | Orth, P. | 登録日 | 2020-05-17 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.388 Å) | 主引用文献 | Structure of human plasma factor XIIa in complex with (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 8h) To Be Published
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6Z29
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![BU of 6z29 by Molmil](/molmil-images/mine/6z29) | Structure of eIF4G1 (37-49) - PUB1 RRM3 chimera in solution | 分子名称: | Eukaryotic initiation factor 4F subunit p150,Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 | 著者 | Chaves-Arquero, B, Martinez-Lumbreras, S, Perez-Canadillas, J.M. | 登録日 | 2020-05-15 | 公開日 | 2021-05-26 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly. Front Mol Biosci, 9, 2022
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7C4C
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7C4B
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7C45
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7C47
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6Z2C
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![BU of 6z2c by Molmil](/molmil-images/mine/6z2c) | Engineered lipocalin C3A5 in complex with a transition state analog | 分子名称: | 1,7,8,9,10,10-hexachloro-4-carboxypentyl-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione, Neutrophil gelatinase-associated lipocalin | 著者 | Skerra, A, Eichinger, A. | 登録日 | 2020-05-15 | 公開日 | 2021-05-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of an engineered lipocalin that catalyzes a Diels-Alder reaction To be published
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6X0B
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6WZL
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![BU of 6wzl by Molmil](/molmil-images/mine/6wzl) | LY3041658 Fab bound to CXCL7 | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, C-X-C motif chemokine 7, LY3041658 Fab heavy chain, ... | 著者 | Durbin, J.D, Druzina, Z. | 登録日 | 2020-05-14 | 公開日 | 2020-11-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
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6WZM
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![BU of 6wzm by Molmil](/molmil-images/mine/6wzm) | LY3041658 Fab bound to CXCL8 | 分子名称: | 1,2-ETHANEDIOL, Interleukin-8, LY3041658 Fab heavy chain, ... | 著者 | Durbin, J.D, Druzina, Z. | 登録日 | 2020-05-14 | 公開日 | 2020-11-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
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6WZJ
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![BU of 6wzj by Molmil](/molmil-images/mine/6wzj) | LY3041658 Fab bound to CXCL2 | 分子名称: | C-X-C motif chemokine 2, LY3041658 Fab Heavy Chain, LY3041658 Fab Light Chain | 著者 | Durbin, J.D, Druzina, Z. | 登録日 | 2020-05-14 | 公開日 | 2020-11-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
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6WZP
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![BU of 6wzp by Molmil](/molmil-images/mine/6wzp) | The crystal structure of 4-vinylbenzoate-bound T252A mutant CYP199A4 | 分子名称: | 4-ethenylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... | 著者 | Coleman, T, Bruning, J.B, Bell, S.G. | 登録日 | 2020-05-14 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Understanding the Mechanistic Requirements for Efficient and Stereoselective Alkene Epoxidation by a Cytochrome P450 Enzyme Acs Catalysis, 11, 2021
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7C43
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7C42
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7C41
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![BU of 7c41 by Molmil](/molmil-images/mine/7c41) | KRAS G12V and H-REV107 peptide complex | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, HRAS-like suppressor 3, ... | 著者 | Han, C.W, Jeong, M.S, Jang, S.B. | 登録日 | 2020-05-14 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.276 Å) | 主引用文献 | A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants. Cancers (Basel), 12, 2020
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7C40
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![BU of 7c40 by Molmil](/molmil-images/mine/7c40) | MgGDP bound KRAS G12V | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Han, C.W, Jeong, M.S, Jang, S.B. | 登録日 | 2020-05-14 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.516 Å) | 主引用文献 | A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants. Cancers (Basel), 12, 2020
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6Z1T
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![BU of 6z1t by Molmil](/molmil-images/mine/6z1t) | MAP3K14 (NIK) in complex with 4S/3694 | 分子名称: | 4S/3694, Mitogen-activated protein kinase kinase kinase 14 | 著者 | Jacoby, E, van Vlijmen, H, Querolle, O, Stansfield, I, Meerpoel, L, Versele, M, Hynd, G, Attar, R. | 登録日 | 2020-05-14 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma Future Drug Discov, 2, 2020
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6Z1Q
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![BU of 6z1q by Molmil](/molmil-images/mine/6z1q) | MAP3K14 (NIK) in complex with DesF-3R/4076 | 分子名称: | DesF-3R/4076, Mitogen-activated protein kinase kinase kinase 14 | 著者 | Jacoby, E, van Vlijmen, H, Querolle, O, Stansfield, I, Meerpoel, L, Versele, M, Hynd, G, Attar, R. | 登録日 | 2020-05-14 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | FEP+ calculations predict a stereochemical SAR switch for first-in-class indoline NIK inhibitors for multiple myeloma Future Drug Discov, 2, 2020
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6Z1R
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![BU of 6z1r by Molmil](/molmil-images/mine/6z1r) | bovine ATP synthase F1-peripheral stalk domain, state 2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-05-14 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Z1U
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![BU of 6z1u by Molmil](/molmil-images/mine/6z1u) | bovine ATP synthase F1c8-peripheral stalk domain, state 3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... | 著者 | Spikes, T, Montgomery, M.G, Walker, J.E. | 登録日 | 2020-05-14 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-30 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure of the dimeric ATP synthase from bovine mitochondria. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WZK
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![BU of 6wzk by Molmil](/molmil-images/mine/6wzk) | LY3041658 Fab bound to CXCL3 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, C-X-C motif chemokine 3, ... | 著者 | Durbin, J.D, Druzina, Z. | 登録日 | 2020-05-14 | 公開日 | 2020-11-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody. Mabs, 12
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6Z1E
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6Z1D
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6Z1F
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![BU of 6z1f by Molmil](/molmil-images/mine/6z1f) | CryoEM structure of Rubisco Activase with its substrate Rubisco from Nostoc sp. (strain PCC7120) | 分子名称: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Wang, H, Bracher, A, Flecken, M, Popilka, L, Hartl, F.U, Hayer-Hartl, M. | 登録日 | 2020-05-13 | 公開日 | 2020-09-23 | 最終更新日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes. Cell, 183, 2020
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