PDB: 235458 件ウェブページステータス検索Chemie searchBIRD

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4EHR	Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide 分子名称: 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide, Bcl-2-like protein 1, IMIDAZOLE 著者 Schroeder, G.M, Wei, D, Banfi, P, Cai, Z, Lippy, J, Menichincheri, M, Modugno, M, Naglich, J, Penhallow, B, Perez, H.L, Sack, J, Schmidt, R.J, Tebben, A, Yan, C, Zhang, L, Galvani, A, Lombardo, L.J, Borzilleri, R.M. 登録日 2012-04-03 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorg.Med.Chem.Lett., 22, 2012
4EHS	Crystal structure of Helicobacter pylori DnaG Primase C terminal domain 分子名称: BETA-MERCAPTOETHANOL, DNA primase 著者 Abdul Rehman, S.A, Gourinath, S. 登録日 2012-04-04 公開日 2013-05-01 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal structure and mode of helicase binding of the C-terminal domain of primase from Helicobacter pylori J.Bacteriol., 195, 2013
4EHT	Activator of the 2-Hydroxyisocaproyl-CoA dehydratase from Clostridium difficile with bound ADP 分子名称: ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, AMMONIUM ION, ... 著者 Knauer, S.H, Dobbek, H. 登録日 2012-04-04 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 On the ATP-Dependent Activation of the Radical Enzyme (R)-2-Hydroxyisocaproyl-CoA Dehydratase. Biochemistry, 51, 2012
4EHU	Activator of the 2-Hydroxyisocaproyl-CoA Dehydratase from Clostridium difficile with bound ADPNP 分子名称: ACETATE ION, Activator of 2-hydroxyisocaproyl-CoA dehydratase, IRON/SULFUR CLUSTER, ... 著者 Knauer, S.H, Dobbek, H. 登録日 2012-04-04 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 On the ATP-Dependent Activation of the Radical Enzyme (R)-2-Hydroxyisocaproyl-CoA Dehydratase. Biochemistry, 51, 2012
4EHV	Human p38 MAP kinase in complex with NP-F10 and RL87 分子名称: (1R,5S)-3-(4-chlorobenzoyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one, Mitogen-activated protein kinase 14, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine 著者 Over, B, Gruetter, C, Waldmann, H, Rauh, D. 登録日 2012-04-04 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
4EHW	Crystal structure of LpxK from Aquifex aeolicus at 2.3 angstrom resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, Tetraacyldisaccharide 4'-kinase 著者 Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. 登録日 2012-04-04 公開日 2012-08-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
4EHX	Crystal structure of LpxK from Aquifex aeolicus at 1.9 angstrom resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. 登録日 2012-04-04 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
4EHY	Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. 登録日 2012-04-04 公開日 2012-08-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
4EHZ	The Jak1 kinase domain in complex with inhibitor 分子名称: 1,2-ETHANEDIOL, 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK1 著者 Lupardus, P.J, Steffek, M. 登録日 2012-04-04 公開日 2012-07-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.174 Å) 主引用文献 Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. J.Med.Chem., 55, 2012
4EI0	Crystal structure of a DUF4466 family protein (PARMER_03218) from Parabacteroides merdae ATCC 43184 at 2.00 A resolution 分子名称: GLYCEROL, uncharacterized hypothetical protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-04-04 公開日 2012-05-30 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a hypothetical protein (PARMER_03218) from Parabacteroides merdae ATCC 43184 at 2.00 A resolution To be published
4EI2	Crystal Structures of MthK RCK gating ring bound to Barium 分子名称: BARIUM ION, Calcium-gated potassium channel mthK 著者 Smith, F.J, Cingolani, G, Rothberg, B.S. 登録日 2012-04-04 公開日 2012-12-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.108 Å) 主引用文献 Crystal Structure of a Ba(2+)-Bound Gating Ring Reveals Elementary Steps in RCK Domain Activation. Structure, 20, 2012
4EI4	JAK1 kinase (JH1 domain) in complex with compound 20 分子名称: (1R,3R)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8H)-yl)cyclohexanol, Tyrosine-protein kinase JAK1 著者 Eigenbrot, C, Steffek, M. 登録日 2012-04-04 公開日 2012-07-04 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2. J.Med.Chem., 55, 2012
4EI5	Crystal Structure of XV19 TCR in complex with CD1d-sulfatide C24:1 分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Patel, O, Gras, S, Rossjohn, J. 登録日 2012-04-04 公開日 2012-07-25 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat.Immunol., 13, 2012
4EI6	Structure of XV19 Valpha1-Vbeta16 Type-II Natural Killer T cell receptor 分子名称: Valpha1 XV19 Type II Natural Killer T cell receptor (mouse variable domain, human constant domain), Vbeta16 XV19 Type II Natural Killer T cell receptor (mouse variable domain 著者 Patel, O, Rossjohn, J. 登録日 2012-04-04 公開日 2012-07-25 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor. Nat.Immunol., 13, 2012
4EI7	Crystal structure of Bacillus cereus TubZ, GDP-form 分子名称: GUANOSINE-5'-DIPHOSPHATE, Plasmid replication protein RepX 著者 Hayashi, I, Hoshino, S. 登録日 2012-04-05 公開日 2012-08-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J.Biol.Chem., 287, 2012
4EI8	Crystal structure of Bacillus cereus TubZ, apo-form 分子名称: Plasmid replication protein RepX 著者 Hayashi, I, Hoshino, S. 登録日 2012-04-05 公開日 2012-08-15 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J.Biol.Chem., 287, 2012
4EI9	Crystal structure of Bacillus cereus TubZ, GTP-form 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Plasmid replication protein RepX 著者 Hayashi, I, Hoshino, S. 登録日 2012-04-05 公開日 2012-08-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Filament formation of the FtsZ/tubulin-like protein TubZ from the Bacillus cereus pXO1 plasmid. J.Biol.Chem., 287, 2012
4EIA	Activator of the 2-Hydroxyisocaproyl-CoA Dehydratase from Clostridium difficile without nucleotide 分子名称: Activator of 2-hydroxyisocaproyl-CoA dehydratase, IRON/SULFUR CLUSTER 著者 Knauer, S.H, Dobbek, H. 登録日 2012-04-05 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 On the ATP-Dependent Activation of the Radical Enzyme (R)-2-Hydroxyisocaproyl-CoA Dehydratase. Biochemistry, 51, 2012
4EIB	Crystal Structure of Circular Permuted CBM21 (CP90) Gives Insight into the Altered Selectivity on Carbohydrate Binding. 分子名称: ACETATE ION, AMMONIUM ION, CHLORIDE ION, ... 著者 Stephen, P, Cheng, K.C, Lyu, P.C. 登録日 2012-04-05 公開日 2012-12-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal structure of circular permuted RoCBM21 (CP90): dimerisation and proximity of binding sites Plos One, 7, 2012
4EIC	Crystal structure of reduced cytochrome c6 from Synechococcus sp. PCC 7002 at ultra-high resolution 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cytochrome c6, HEME C 著者 Krzywda, S, Bialek, W, Jaskolski, M, Szczepaniak, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (0.84 Å) 主引用文献 Cytochrome c6 and c6C from Synechococcus sp. PCC 7002 - structure and function. To be Published
4EID	Crystal structure of cytochrome c6 Q57V mutant from Synechococcus sp. PCC 7002 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cytochrome c6, HEME C 著者 Krzywda, S, Bialek, W, Zatwarnicki, P, Jaskolski, M, Szczepaniak, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Cytochrome c6 and c6C from Synechococcus sp. PCC 7002 - structure and function. To be Published
4EIE	Crystal structure of cytochrome c6C from Synechococcus sp. PCC 7002 分子名称: CHLORIDE ION, Cytochrome c6, HEME C, ... 著者 Krzywda, S, Bialek, W, Zatwarnicki, P, Jaskolski, M, Szczepaniak, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Cytochrome c6 and c6C from Synechococcus sp. PCC 7002 - structure and function. To be Published
4EIF	Crystal structure of cytochrome c6C L50Q mutant from Synechococcus sp. PCC 7002 分子名称: CHLORIDE ION, Cytochrome c6, HEME C, ... 著者 Krzywda, S, Bialek, W, Zatwarnicki, P, Jaskolski, M, Szczepaniak, A. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Cytochrome c6 and c6C from Synechococcus sp. PCC 7002 - structure and function. To be Published
4EIG	CA1698 camel antibody fragment in complex with DHFR 分子名称: CA1698 camel antibody fragment, Dihydrofolate reductase 著者 Oyen, D, Srinivasan, V. 登録日 2012-04-05 公開日 2013-04-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli. Biochim.Biophys.Acta, 1834, 2013
4EIH	Crystal structure of Arg SH2 domain 分子名称: Abelson tyrosine-protein kinase 2, CHLORIDE ION 著者 Liu, W, MacGrath, S.M, Koleske, A.J, Boggon, T.J. 登録日 2012-04-05 公開日 2013-04-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin. J.Biol.Chem., 289, 2014

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