5MQQ
 
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6TOR
 | | human O-phosphoethanolamine phospho-lyase | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Ethanolamine-phosphate phospho-lyase, GLYCEROL | | 著者 | Vettraino, C, Donini, S, Parisini, E. | | 登録日 | 2019-12-11 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural characterization of human O-phosphoethanolamine phospho-lyase.
Acta Crystallogr.,Sect.F, 76, 2020
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7E6C
 | | Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis | | 分子名称: | (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, 1,2-ETHANEDIOL, Cysteine desulfurase SufS, ... | | 著者 | Nakamura, R, Takahashi, Y, Fujishiro, T. | | 登録日 | 2021-02-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
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7E6F
 | | Crystal structure of PMP-bound form of cysteine desulfurase SufS R376A from Bacillus subtilis in L-cycloserine-inhibition | | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ... | | 著者 | Nakamura, R, Takahashi, Y, Fujishiro, T. | | 登録日 | 2021-02-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
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7E6D
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7E6B
 | | Crystal structure of PMP-bound form of cysteine desulfurase SufS C361A from Bacillus subtilis | | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Cysteine desulfurase SufS, ... | | 著者 | Nakamura, R, Takahashi, Y, Fujishiro, T. | | 登録日 | 2021-02-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.
Febs J., 289, 2022
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6QXZ
 | | Solution structure of the ASHH2 CW domain with the N-terminal histone H3 tail mimicking peptide monomethylated on lysine 4 | | 分子名称: | ALA-ARG-THR-MLZ-GLN-THR-ALA-ARG-TYR, Histone-lysine N-methyltransferase ASHH2, ZINC ION | | 著者 | Dobrovolska, O, Madeleine, N, Teigen, K, Halskau, O, Bril'kov, M. | | 登録日 | 2019-03-08 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection.
Febs J., 287, 2020
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6RFT
 | | Crystal structure of Eis2 from Mycobacterium abscessus bound to Acetyl-CoA | | 分子名称: | ACETYL COENZYME *A, Uncharacterized N-acetyltransferase D2E36_21790 | | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | | 登録日 | 2019-04-16 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
Febs J., 286, 2019
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6RGU
 | | Photorhabdus asymbiotica lectin PHL in complex with 3-O-methyl-D-glucose | | 分子名称: | 3-O-methyl-beta-D-glucopyranose, CHLORIDE ION, Lectin PHL, ... | | 著者 | Houser, J, Fujdiarova, E, Jancarikova, G, Wimmerova, M. | | 登録日 | 2019-04-17 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Febs J., 288, 2021
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6RFX
 | | Crystal structure of Eis2 from Mycobacterium abscessus | | 分子名称: | ACETATE ION, CITRIC ACID, Eis2, ... | | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | | 登録日 | 2019-04-16 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
Febs J., 286, 2019
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5HKE
 | | bile salt hydrolase from Lactobacillus salivarius | | 分子名称: | Bile salt hydrolase, PHOSPHATE ION | | 著者 | Hu, X.-J. | | 登録日 | 2016-01-14 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of bile salt hydrolase from Lactobacillus salivarius.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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9CPM
 | | Thermus thermophilus HB27 laccase (Tth-Lac) mutant with partial deletion of beta-hairpin sequence | | 分子名称: | COPPER (II) ION, GLYCEROL, Laccase | | 著者 | Lee, J, Miranda-Zaragoza, B, Rodriguez-Almazan, C, Strynadka, N.C.J. | | 登録日 | 2024-07-18 | | 公開日 | 2025-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Function Relationship of the beta-Hairpin of Thermus thermophilus HB27 Laccase.
Int J Mol Sci, 26, 2025
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6RGW
 | | Photorhabdus asymbiotica lectin PHL in complex with O-methylated PGL-1-derived disaccharide | | 分子名称: | 1,2-ETHANEDIOL, 3,6-O-dimethyl-D-glucose, 4-(2-azanylethoxy)phenol, ... | | 著者 | Houser, J, Fujdiarova, E, Jancarikova, G, Wimmerova, M. | | 登録日 | 2019-04-17 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Heptabladed beta-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Febs J., 288, 2021
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2WDQ
 | | E. coli succinate:quinone oxidoreductase (SQR) with carboxin bound | | 分子名称: | 2-METHYL-N-PHENYL-5,6-DIHYDRO-1,4-OXATHIINE-3-CARBOXAMIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | | 著者 | Ruprecht, J, Yankovskaya, V, Maklashina, E, Iwata, S, Cecchini, G. | | 登録日 | 2009-03-25 | | 公開日 | 2009-08-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of Escherichia coli succinate:quinone oxidoreductase with an occupied and empty quinone-binding site.
J. Biol. Chem., 284, 2009
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6DCN
 | | Bcl-xL complex with Beclin 1 BH3 domain T108pThr | | 分子名称: | BCL-xl protein, Beclin-1 | | 著者 | Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D. | | 登録日 | 2018-05-07 | | 公開日 | 2018-05-23 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.444 Å) | | 主引用文献 | Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
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2LHT
 | | Solution structure of Venturia inaequalis cellophane-induced 1 protein (ViCin1) domains 1 and 2 | | 分子名称: | Cellophane-induced protein 1 | | 著者 | Mesarich, C.H, Schmitz, M, Tremouilhac, P, Greenwood, D.R, Mcgillivray, D.J, Templeton, M.D, Dingley, A.J. | | 登録日 | 2011-08-16 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure, dynamics and domain organization of the repeat protein Cin1 from the apple scab fungus.
Biochim.Biophys.Acta, 1824, 2012
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8Y55
 | | Crystal Structure of NAMPT-PF403 | | 分子名称: | (13~{a}~{S})-6,7-dimethoxy-9,11,12,13,13~{a},14-hexahydrophenanthro[9,10-f]indolizin-3-ol, DI(HYDROXYETHYL)ETHER, Nicotinamide phosphoribosyltransferase | | 著者 | Yu, S.S, Liu, Y.B, Li, Y. | | 登録日 | 2024-01-31 | | 公開日 | 2025-02-19 | | 最終更新日 | 2025-06-25 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Thermal proteome profiling (TPP) reveals NAMPT as the anti-glioma target of phenanthroindolizidine alkaloid PF403.
Acta Pharm Sin B, 15, 2025
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8YRT
 | | Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis in the holo form obtained at pH 7.0 | | 分子名称: | Aminotransferase class IV, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Matyuta, I.O, Bakunova, A.K, Minyaev, M.E, Popov, V.O, Boyko, K.M. | | 登録日 | 2024-03-21 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Incorporation of pyridoxal-5'-phosphate into the apoenzyme: A structural study of D-amino acid transaminase from Haliscomenobacter hydrossis.
Biochim Biophys Acta Proteins Proteom, 1873, 2024
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8YRU
 | | Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis (apo form) after 15 sec of soaking with phenylhydrazine | | 分子名称: | ACETATE ION, Aminotransferase class IV, [6-methyl-5-oxidanyl-4-[(2-phenylhydrazinyl)methyl]pyridin-3-yl]methyl dihydrogen phosphate | | 著者 | Matyuta, I.O, Bakunova, A.K, Minyaev, M.E, Popov, V.O, Boyko, K.M. | | 登録日 | 2024-03-21 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Incorporation of pyridoxal-5'-phosphate into the apoenzyme: A structural study of D-amino acid transaminase from Haliscomenobacter hydrossis.
Biochim Biophys Acta Proteins Proteom, 1873, 2024
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5HMJ
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6DCO
 | | Bcl-xL complex with Beclin 1 BH3 domain T108D | | 分子名称: | Bcl-2-like protein 1,Bcl-2-like protein 1, Beclin-1, CHLORIDE ION | | 著者 | Lee, E.F, Smith, B.J, Smith, N.A, Yao, S, Fairlie, W.D. | | 登録日 | 2018-05-07 | | 公開日 | 2018-05-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1.
Autophagy, 15, 2019
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8YP5
 | | The structure of MAP2K4 complexed with 5Z7-oxozeaenol | | 分子名称: | (3S,5Z,8S,9S,11E)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, Dual specificity mitogen-activated protein kinase kinase 4, MAGNESIUM ION | | 著者 | Yumura, S, Kinishita, T. | | 登録日 | 2024-03-15 | | 公開日 | 2025-01-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conserved gatekeeper methionine regulates the binding and access of kinase inhibitors to ATP sites of MAP2K1, 4, and 7: Clues for developing selective inhibitors.
Bioorg.Med.Chem.Lett., 112, 2024
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6RPV
 | | Extremely stable monomeric variant of human cystatin C with single amino acid substitution | | 分子名称: | Cystatin-C | | 著者 | Zhukov, I, Rodziewicz-Motowidlo, S, Maszota-Zieleniak, M, Jurczak, P, Kozak, M. | | 登録日 | 2019-05-14 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-11-13 | | 実験手法 | SOLUTION NMR, SOLUTION SCATTERING | | 主引用文献 | NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution.
Febs J., 287, 2020
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7CYG
 | | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation | | 分子名称: | Transporter, sodium/bile acid symporter family | | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | | 登録日 | 2020-09-03 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.198 Å) | | 主引用文献 | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter.
Acta Crystallogr D Struct Biol, 77, 2021
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6RFY
 | | Crystal structure of Eis2 form Mycobacterium abscessus | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Eis2, SULFATE ION | | 著者 | Blaise, M, Kremer, L, Olieric, V, Alsarraf, H, Ung, K.L. | | 登録日 | 2019-04-16 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
Febs J., 286, 2019
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