PDB: 23413 件ウェブページステータス検索Chemie searchBIRD

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8QTR	Cryo-EM structure of the FB-bound yeast Ceramide Synthase 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, AMMONIUM ION, Ceramide synthase LAC1, ... 著者 Schaefer, J, Clausmeyer, L, Koerner, C, Moeller, A, Froehlich, F. 登録日 2023-10-13 公開日 2024-10-23 最終更新日 2025-03-26 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the yeast ceramide synthase. Nat.Struct.Mol.Biol., 32, 2025
7YW9	Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG 分子名称: ACETATE ION, CmnC, D-ARGININE, ... 著者 Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. 登録日 2022-08-22 公開日 2023-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer. Front Chem, 10, 2022
4WU4	Crystal structure of E. faecalis DNA binding domain LiaRD191N complexed with 22bp DNA 分子名称: DNA (5'-D(P*AP*AP*AP*TP*CP*GP*TP*TP*CP*TP*TP*AP*AP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*TP*AP*AP*GP*AP*AP*CP*GP*AP*TP*TP*T)-3'), GLYCEROL, ... 著者 Davlieva, M, Shamoo, Y. 登録日 2014-10-31 公開日 2015-05-06 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A variable DNA recognition site organization establishes the LiaR-mediated cell envelope stress response of enterococci to daptomycin. Nucleic Acids Res., 43, 2015
5IQE	Aminoglycoside Phosphotransferase (2'')-Ia (CTD of AAC(6')-Ie/APH(2'')-Ia) in complex with GMPPNP, Magnesium, and Neomycin B 分子名称: Bifunctional AAC/APH, GLYCEROL, MAGNESIUM ION, ... 著者 Caldwell, S.J, Berghuis, A.M. 登録日 2016-03-10 公開日 2016-05-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2)-Ia. Structure, 24, 2016
8FOJ	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOC	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
3N8D	Crystal structure of Staphylococcus aureus VRSA-9 D-Ala:D-Ala ligase 分子名称: CHLORIDE ION, D-alanine--D-alanine ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Saul, F.A, Haouz, A, Meziane-Cherif, D. 登録日 2010-05-28 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis of vancomycin dependence in VanA-type Staphylococcus aureus VRSA-9. J.Bacteriol., 192, 2010
8FOH	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8Q1B	III2-IV1 respiratory supercomplex from S. pombe 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, CALCIUM ION, CARDIOLIPIN, ... 著者 Moe, A, Brzezinski, P. 登録日 2023-07-31 公開日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and function of the S. pombe III-IV-cyt c supercomplex. Proc.Natl.Acad.Sci.USA, 120, 2023
8FOE	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOK	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOD	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FS5	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 3 (open 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS4	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2 (open 9-1-1 ring and flexibly bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS3	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 1 (open 9-1-1 and shoulder bound DNA only) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS8	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1 encircling fully bound DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS7	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5 (closed 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8FS6	Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4 (partially closed 9-1-1 and stably bound chamber DNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DDC1 isoform 1, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2023-01-09 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology. Biorxiv, 2023
8RVO	Proteasomal late precursor complex from pre1-1, state 1 分子名称: Probable proteasome subunit alpha type-7, Proteasome assembly chaperone 2, Proteasome chaperone 1, ... 著者 Mark, E, Ramos, P.C, Kayser, F, Hoeckendorff, J, Dohmen, R.J, Wendler, P. 登録日 2024-02-01 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Structural roles of Ump1 and beta-subunit propeptides in proteasome biogenesis. Life Sci Alliance, 7, 2024
8RVP	Proteasomal late precursor complex from pre1-1, state 2 分子名称: Probable proteasome subunit alpha type-7, Proteasome assembly chaperone 2, Proteasome chaperone 1, ... 著者 Mark, E, Ramos, P.C, Kayser, F, Hoeckendorff, J, Dohmen, R.J, Wendler, P. 登録日 2024-02-01 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (2.28 Å) 主引用文献 Structural roles of Ump1 and beta-subunit propeptides in proteasome biogenesis. Life Sci Alliance, 7, 2024
8RVQ	20S proteasome from pre1-1 分子名称: Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... 著者 Mark, E, Ramos, P.C, Kayser, F, Hoeckendorff, J, Dohmen, R.J, Wendler, P. 登録日 2024-02-01 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (2.02 Å) 主引用文献 Structural roles of Ump1 and beta-subunit propeptides in proteasome biogenesis. Life Sci Alliance, 7, 2024
8RVL	Proteasomal late precursor complex from pre1-1 分子名称: Probable proteasome subunit alpha type-7, Proteasome assembly chaperone 2, Proteasome chaperone 1, ... 著者 Mark, E, Ramos, P.C, Kayser, F, Hoeckendorff, J, Dohmen, R.J, Wendler, P. 登録日 2024-02-01 公開日 2024-09-11 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (2.14 Å) 主引用文献 Structural roles of Ump1 and beta-subunit propeptides in proteasome biogenesis. Life Sci Alliance, 7, 2024
5D75	Crystal structure of Human FKBD25 in complex with FK506 分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Peptidyl-prolyl cis-trans isomerase FKBP3 著者 Rajan, S, Prakash, A, Yoon, H.S. 登録日 2015-08-13 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506. Protein Sci., 25, 2016
8RIF	Cryo-EM structure of the MCM double hexamer loaded onto dsDNA. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (53-MER), ... 著者 Miller, T.C.R, Lim, C.T, Diffley, J.F.X, Costa, A. 登録日 2023-12-18 公開日 2025-01-01 実験手法 ELECTRON MICROSCOPY (2.79 Å) 主引用文献 Inhibition of Origin Recognition Complex by Cyclin Dependent Kinase Reveals Alternate Mechanism of MCM Loading To Be Published
7CMS	Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with chuangxinmycin 分子名称: (5~{S},6~{R})-5-methyl-7-thia-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-6-carboxylic acid, PHOSPHATE ION, Tryptophan--tRNA ligase 著者 Lyu, G, Fan, S, Jin, Y, Zou, S, Wu, G, Yang, Z. 登録日 2020-07-28 公開日 2021-08-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into the specific interaction between Geobacillus stearothermophilus tryptophanyl-tRNA synthetase and antimicrobial Chuangxinmycin. J.Biol.Chem., 298, 2022

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