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2JAW
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BU of 2jaw by Molmil
Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 5-bromovinyldeoxyuridine 5'-monophosphate
分子名称: (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION
著者Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P.
登録日2006-11-30
公開日2007-11-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
2JAU
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Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 3'-azidothymidine 5'- monophosphate
分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION, ...
著者Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P.
登録日2006-11-30
公開日2007-12-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues.
Biochemistry, 46, 2007
5ZZN
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BU of 5zzn by Molmil
Crystal structure of photosystem II from an SQDG-deficient mutant of Thermosynechococcus elongatus
分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Nakajima, Y, Umena, Y, Nagao, R, Endo, K, Kobayashi, K, Akita, F, Suga, M, Wada, H, Noguchi, T, Shen, J.R.
登録日2018-06-03
公開日2018-08-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Thylakoid membrane lipid sulfoquinovosyl-diacylglycerol (SQDG) is required for full functioning of photosystem II inThermosynechococcus elongatus.
J. Biol. Chem., 293, 2018
8F2U
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BU of 8f2u by Molmil
Human CCC complex
分子名称: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
著者Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
登録日2022-11-08
公開日2023-05-24
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
5DNF
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BU of 5dnf by Molmil
Crystal structure of CC chemokine 5 (CCL5) oligomer in complex with heparin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, C-C motif chemokine 5, ...
著者Liang, W.G, Tang, W.
登録日2015-09-10
公開日2016-04-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.549 Å)
主引用文献Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
8FL0
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BU of 8fl0 by Molmil
Human nucleolar pre-60S ribosomal subunit (State H)
分子名称: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FL4
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Human nuclear pre-60S ribosomal subunit (State I3)
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
5F7Z
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BU of 5f7z by Molmil
Crystal structure of Double Mutant S12T and N87T of Adenosine/Methylthioadenosine Phosphorylase from Schistosoma mansoni in APO Form
分子名称: Methylthioadenosine phosphorylase, PHOSPHATE ION
著者Torini, J.R, Brandao-Neto, J, DeMarco, R, Pereira, H.M.
登録日2015-12-08
公開日2016-12-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Schistosoma mansoni Adenosine Phosphorylase/5'-Methylthioadenosine Phosphorylase and Its Importance on Adenosine Salvage Pathway.
PLoS Negl Trop Dis, 10, 2016
2JVW
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BU of 2jvw by Molmil
Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117
分子名称: Uncharacterized protein
著者Aramini, J.M, Rossi, P, Wang, D, Nwosu, C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-09-26
公開日2007-10-16
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.
Proteins, 79, 2011
2JVD
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BU of 2jvd by Molmil
Solution NMR structure of the folded N-terminal fragment of UPF0291 protein ynzC from Bacillus subtilis. Northeast Structural Genomics target SR384-1-46
分子名称: UPF0291 protein ynzC
著者Aramini, J.M, Sharma, S, Huang, Y.J, Zhao, L, Owens, L.A, Stokes, K, Jiang, M, Xiao, R, Baran, M.C, Swapna, G.V.T, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-09-18
公開日2007-10-02
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis.
Proteins, 72, 2008
1ZGY
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BU of 1zgy by Molmil
Structural and Biochemical Basis for Selective Repression of the Orphan Nuclear Receptor LRH-1 by SHP
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Nuclear receptor subfamily 0, ...
著者Li, Y, Choi, M, Suino, K, Kovach, A, Daugherty, J, Kliewer, S.A, Xu, H.E.
登録日2005-04-22
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1ZLL
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BU of 1zll by Molmil
NMR Structure of Unphosphorylated Human Phospholamban Pentamer
分子名称: Cardiac phospholamban
著者Oxenoid, K, Chou, J.J.
登録日2005-05-06
公開日2005-08-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of phospholamban pentamer reveals a channel-like architecture in membranes
Proc.Natl.Acad.Sci.USA, 102, 2005
1P3J
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BU of 1p3j by Molmil
Adenylate Kinase from Bacillus subtilis
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Bae, E, Phillips Jr, G.N.
登録日2003-04-17
公開日2004-05-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases.
J.Biol.Chem., 279, 2004
6BOH
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BU of 6boh by Molmil
Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Korostelev, A.A.
登録日2017-11-20
公開日2018-05-23
最終更新日2025-03-19
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
2L3Y
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BU of 2l3y by Molmil
Solution structure of mouse IL-6
分子名称: Interleukin-6
著者Veverka, V, Redpath, N.T, Carrington, B, Muskett, F.W, Taylor, R.J, Henry, A.J, Carr, M.D.
登録日2010-09-25
公開日2011-09-28
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
J.Biol.Chem., 287, 2012
2CN7
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BU of 2cn7 by Molmil
Recombinant human H ferritin, K86Q, E27D and E107D mutant
分子名称: CALCIUM ION, FERRITIN HEAVY CHAIN, GLYCEROL
著者Toussaint, L, Crichton, R.R, Declercq, J.P.
登録日2006-05-18
公開日2006-12-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献High-Resolution X-Ray Structures of Human Apoferritin H-Chain Mutants Correlated with Their Activity and Metal-Binding Sites.
J.Mol.Biol., 365, 2007
2L9H
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BU of 2l9h by Molmil
Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data
分子名称: C-C motif chemokine 5
著者Wang, X, Watson, C.M, Sharp, J.S, Handel, T.M, Prestegard, J.H.
登録日2011-02-09
公開日2011-06-22
最終更新日2024-11-27
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data.
Structure, 19, 2011
2NOM
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BU of 2nom by Molmil
Terminal uridylyl transferase 4 from Trypanosoma brucei with bound dUTP
分子名称: DEOXYURIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase
著者Luecke, H, Stagno, J.
登録日2006-10-25
公開日2007-02-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UTP-bound and Apo Structures of a Minimal RNA Uridylyltransferase.
J.Mol.Biol., 366, 2007
2HYN
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BU of 2hyn by Molmil
Complete ensemble of NMR structures of unphosphorylated human phospholamban pentamer
分子名称: Cardiac phospholamban
著者Potluri, S, Yan, A.K, Chou, J.J, Donald, B.R, Bailey-Kellogg, C.
登録日2006-08-07
公開日2006-08-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure determination of symmetric homo-oligomers by a complete search of symmetry configuration space, using NMR restraints and van der Waals packing.
Proteins, 65, 2006
2ORI
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BU of 2ori by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (A193V/Q199R/)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Counago, R, Shamoo, Y, Wilson, C.J, Wu, G, Myers, J.
登録日2007-02-02
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (A193V/Q199R/)
To be Published
6Y05
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BU of 6y05 by Molmil
Crystal structure of the cAMP-dependent protein kinase A cocrystallized with adenine and PKI (5-24)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENINE, ...
著者Oebbeke, M, Wienen-Schmidt, B, Heine, A, Klebe, G.
登録日2020-02-06
公開日2021-02-17
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Fragment based drug design - Small chemical changes of fragments effecting big changes in binding
To Be Published
6L1L
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BU of 6l1l by Molmil
Apo-BacF structure from Bacillus subtillis
分子名称: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Balasubramanian, G, Deshmukh, A.A.
登録日2019-09-29
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6Y1P
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BU of 6y1p by Molmil
Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)
分子名称: 3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid, Aldo-keto reductase family 1 member B1, CITRIC ACID, ...
著者Hubert, L.-S, Ley, M, Heine, A, Klebe, G.
登録日2020-02-13
公開日2021-02-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.94 Å)
主引用文献Human Aldose Reductase Mutant L300/301A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)
To Be Published
6L4O
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BU of 6l4o by Molmil
Crystal structure of API5-FGF2 complex
分子名称: Apoptosis inhibitor 5, Fibroblast growth factor 2
著者Lee, B.I, Bong, S.M.
登録日2019-10-18
公開日2020-04-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of mRNA export through API5 and nuclear FGF2 interaction.
Nucleic Acids Res., 48, 2020
6L9N
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H2-Ld complexed with A5 peptide
分子名称: MHC, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, b2m
著者Wei, P.C, Yin, L.
登録日2019-11-10
公開日2020-11-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer.
Proc.Natl.Acad.Sci.USA, 118, 2021

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件を2025-07-09に公開中

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