8IMX
 
 | | Cryo-EM structure of GPI-T with a chimeric GPI-anchored protein | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Xu, Y, Li, T, Qu, Q, Li, D. | | 登録日 | 2023-03-07 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structures of liganded glycosylphosphatidylinositol transamidase illuminate GPI-AP biogenesis.
Nat Commun, 14, 2023
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2JAD
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7K18
 | | Cardiac Sodium channel with toxin bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ... | | 著者 | Jiang, D, Catterall, W.A. | | 登録日 | 2020-09-07 | | 公開日 | 2021-01-20 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin.
Nat Commun, 12, 2021
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7KS0
 | | GluK2/K5 with 6-Cyano-7-nitroquinoxaline-2,3-dione (CNQX) | | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | | 登録日 | 2020-11-20 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor.
Elife, 10, 2021
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7KS3
 | | GluK2/K5 with L-Glu | | 分子名称: | Glutamate receptor ionotropic, kainate 2, kainate 5,Green fluorescent protein chimera | | 著者 | Khanra, N, Brown, P.M.G.E, Perozzo, A.M, Bowie, D, Meyerson, J.R. | | 登録日 | 2020-11-20 | | 公開日 | 2021-03-24 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | | 主引用文献 | Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor.
Elife, 10, 2021
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4U2V
 | | Bak BH3-in-Groove dimer (GFP) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Green fluorescent protein,Bcl-2 homologous antagonist/killer | | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | | 登録日 | 2014-07-18 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers.
Mol.Cell, 55, 2014
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5KTG
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8FED
 | | Structure of Mce1-LucB complex from Mycobacterium smegmatis (Map1) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8FEF
 | | Structure of Mce1 transporter from Mycobacterium smegmatis (Map0) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8FEE
 | | Structure of Mce1 transporter from Mycobacterium smegmatis in the absence of LucB (Map2) | | 分子名称: | ABC transporter, ATP-binding protein,Green fluorescent protein chimera, ABC-transporter integral membrane protein, ... | | 著者 | Chen, J, Bhabha, G, Ekiert, D.C. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of an endogenous mycobacterial MCE lipid transporter.
Nature, 620, 2023
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8HCO
 | | Substrate-engaged TOM complex from yeast | | 分子名称: | Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, ... | | 著者 | Zhou, X.Y, Yang, Y.Q, Wang, G.P, Wang, S.S. | | 登録日 | 2022-11-02 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Molecular pathway of mitochondrial preprotein import through the TOM-TIM23 supercomplex.
Nat.Struct.Mol.Biol., 30, 2023
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7SUN
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7SQY
 | | CSDaV GFP mutant | | 分子名称: | Citrus Sudden Death-associated Virus Capsid Protein,Green fluorescent protein,Citrus Sudden Death-associated Virus Capsid Protein | | 著者 | Guo, F, Matsumura, E.E, Falk, B.W. | | 登録日 | 2021-11-07 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Citrus sudden death-associated virus as a new expression vector for rapid in planta production of heterologous proteins, chimeric virions, and virus-like particles.
Biotechnol Rep., 35, 2022
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7SSX
 | | Structure of human Kv1.3 | | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | | 著者 | Meyerson, J.R, Selvakumar, P. | | 登録日 | 2021-11-11 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7SSZ
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7SSY
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7SSV
 | | Structure of human Kv1.3 with Fab-ShK fusion | | 分子名称: | Fab-ShK fusion, heavy chain, light chain, ... | | 著者 | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | | 登録日 | 2021-11-11 | | 公開日 | 2022-06-29 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
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7X5V
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4BDU
 | | Bax BH3-in-Groove dimer (GFP) | | 分子名称: | GREEN FLUORESCENT PROTEIN, APOPTOSIS REGULATOR BAX | | 著者 | Czabotar, P.E, Colman, P.M. | | 登録日 | 2012-10-08 | | 公開日 | 2013-02-13 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
Cell(Cambridge,Mass.), 152, 2013
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4ANJ
 | | MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ... | | 著者 | Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M. | | 登録日 | 2012-03-19 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi.
Mol.Cell, 48, 2012
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7XSU
 | | Cardiac sodium channel in complex with LqhIII | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-like toxin Lqh3, ... | | 著者 | Jiang, D, Catterall, W.A. | | 登録日 | 2022-05-15 | | 公開日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural Basis for Nav1.5 Opening Modulated by a Gating Modifier Toxin
To Be Published
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8DFL
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8ET3
 | | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | 著者 | Ghanbarpour, A, Fei, X, Davis, J.H, Sauer, R.T. | | 登録日 | 2022-10-16 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8F6P
 | | Rat Cardiac Sodium Channel with Ranolazine Bound | | 分子名称: | (R)-ranolazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Lenaeus, M.J, Tonggu, L. | | 登録日 | 2022-11-16 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural Basis for Inhibition of the Cardiac Sodium Channel by the Atypical Antiarrhythmic Drug Ranolazine
To Be Published
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6RMG
 | | Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Korkhov, V.M, Qi, C. | | 登録日 | 2019-05-06 | | 公開日 | 2019-10-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of sterol recognition by human hedgehog receptor PTCH1.
Sci Adv, 5, 2019
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