PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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2GQJ	Solution structure of the two zf-C2H2 like domains(493-575) of human zinc finger protein KIAA1196 分子名称: ZINC ION, Zinc finger protein KIAA1196 著者 Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-21 公開日 2006-10-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the two zf-C2H2 like domains(493-575) of human zinc finger protein KIAA1196 To be Published
2H5G	Crystal structure of human pyrroline-5-carboxylate synthetase 分子名称: Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION 著者 Papagrigoriou, E, Shafqat, N, Turnbull, A.P, Berridge, G, Hozjan, V, Kavanagh, K, Gileadi, O, Smee, C, Bray, J, Gorrec, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) 登録日 2006-05-26 公開日 2006-06-23 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of human pyrroline-5-carboxylate synthetase To be published
4DAY	Crystal structure of the RMI core complex with MM2 peptide from FANCM 分子名称: Fanconi anemia group M protein, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 著者 Hoadley, K.A, Keck, J.L. 登録日 2012-01-13 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome. Proc.Natl.Acad.Sci.USA, 109, 2012
4C0D	Structure of the NOT module of the human CCR4-NOT complex (CNOT1-CNOT2-CNOT3) 分子名称: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 著者 Raisch, T, Jonas, S, Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O. 登録日 2013-08-01 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure and Assembly of the not Module of the Human Ccr4-not Complex Nat.Struct.Mol.Biol., 20, 2013
4FTC	Crystal Structure of the CHK1 分子名称: 1-(5-cyanopyrazin-2-yl)-3-(5-phenyl-1H-pyrazol-3-yl)urea, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
5L91	The 2.2 A crystal structure of CYP109E1 from Bacillus megaterium bound with four corticosterone molecules 分子名称: CORTICOSTERONE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
4FTN	Crystal Structure of the CHK1 分子名称: 4'-{6-methoxy-7-[2-(piperidin-1-yl)ethoxy]-1,2-dihydroindeno[1,2-c]pyrazol-3-yl}biphenyl-4-ol, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4GA7	Crystal structure of human serpinB1 mutant 分子名称: Leukocyte elastase inhibitor 著者 Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. 登録日 2012-07-25 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
2RD8	Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195 分子名称: BETA-MERCAPTOETHANOL, PHOSPHATE ION, Thymidylate synthase 著者 Gibson, L.M, Lovelace, L.L, Lebioda, L. 登録日 2007-09-21 公開日 2008-05-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The R163K Mutant of Human Thymidylate Synthase Is Stabilized in an Active Conformation: Structural Asymmetry and Reactivity of Cysteine 195. Biochemistry, 47, 2008
3CWW	Crystal Structure of IDE-bradykinin complex 分子名称: 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ... 著者 Malito, E, Tang, W.J. 登録日 2008-04-23 公開日 2008-11-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme Biochemistry, 47, 2008
4FZS	Structure of human SNX1 BAR domain 分子名称: Sorting nexin-1 著者 van Weering, J.R.T, Sessions, R.B, Traer, C.J, Kloer, D.P, Bhatia, V.K, Stamou, D, Hurley, J.H, Cullen, P.J. 登録日 2012-07-07 公開日 2013-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular insight into vesicle-to-tubule membrane remodeling by SNX-BAR proteins To be Published
2RFI	Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide 分子名称: Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... 著者 Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2007-09-30 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
4FSW	Crystal Structure of the CHK1 分子名称: 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
2RGZ	Ensemble refinement of the protein crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme 分子名称: Heme oxygenase 2, PROTOPORPHYRIN IX CONTAINING FE 著者 Bianchetti, C.M, Bingman, C.A, Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2007-10-05 公開日 2007-10-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Comparison of Apo- and Heme-bound Crystal Structures of a Truncated Human Heme Oxygenase-2. J.Biol.Chem., 282, 2007
3D45	Crystal structure of mouse PARN in complex with m7GpppG 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Poly(A)-specific ribonuclease PARN 著者 Wu, M, Song, H. 登録日 2008-05-13 公開日 2009-03-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease. Structure, 17, 2009
3D4Q	Pyrazole-based inhibitors of B-Raf kinase 分子名称: (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime, B-Raf proto-oncogene serine/threonine-protein kinase 著者 Morales, T, Vigers, G.P.A, Brandhuber, B.J. 登録日 2008-05-14 公開日 2008-08-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Potent and selective pyrazole-based inhibitors of B-Raf kinase. Bioorg.Med.Chem.Lett., 18, 2008
4G21	Structural basis for the accommodation of bis- and tris-aromatic derivatives in Vitamin D Nuclear Receptor 分子名称: 3-(5'-{[3,4-bis(hydroxymethyl)benzyl]oxy}-2'-ethyl-2-propylbiphenyl-4-yl)pentan-3-ol, Nuclear receptor coactivator 1, Vitamin D3 receptor A 著者 Ciesielski, F, Sato, Y, Moras, D, Rochel, N. 登録日 2012-07-11 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin d nuclear receptor. J.Med.Chem., 55, 2012
3CZF	Crystal structure of HLA-B*2709 complexed with the glucagon receptor (GR) peptide (residues 412-420) 分子名称: BETA-2-MICROGLOBULIN, GLUCAGON RECEPTOR PEPTIDE, GLYCEROL, ... 著者 Loll, B, Fiorillo, M.T, Rueckert, C, Saenger, W, Sorrentino, R, Ziegler, A, Uchanska-Ziegler, B. 登録日 2008-04-29 公開日 2009-04-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection. Front Immunol, 11, 2020
4FTL	Crystal Structure of the CHK1 分子名称: 4'-[7-(hydroxymethyl)-2,4-dihydroindeno[1,2-c]pyrazol-3-yl]biphenyl-4-ol, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
4FTU	Crystal Structure of the CHK1 分子名称: GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-28 公開日 2012-08-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
2RF9	Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide 分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor 著者 Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. 登録日 2007-09-28 公開日 2007-12-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature, 450, 2007
3CH6	Crystal Structure of 11beta-HSD1 Double Mutant (L262R, F278E) Complexed with (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone 分子名称: (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sheriff, S. 登録日 2008-03-07 公開日 2008-06-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 Bioorg.Med.Chem.Lett., 18, 2008
5L92	The 2.1 A crystal structure of CYP109E1 from Bacillus megaterium in complex with corticosterone 分子名称: CORTICOSTERONE, Cytochrome P450, MALONIC ACID, ... 著者 Jozwik, I.K, Thunnissen, A.M.W.H. 登録日 2016-06-09 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium. Febs J., 283, 2016
3D6M	Crystal structure of human caspase-1 with a naturally-occurring Lys319->Arg substitution in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK) 分子名称: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide 著者 Rosen-Wolff, A, Roesler, J, Romanowski, M.J. 登録日 2008-05-19 公開日 2010-03-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mutated, structurally altered caspase-1 with decreased enzymatic and increased RIP2-meditated inflammatory activity leads to a new type of periodic fever (ICE fever). To be Published, 2008
3D7H	A high resolution crystal structure of human glutamate carboxypeptidase II (GCPII) in a complex with DCIBzL, a urea-based inhibitor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Lubkowski, J, Barinka, C. 登録日 2008-05-21 公開日 2008-12-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Interactions between Human Glutamate Carboxypeptidase II and Urea-Based Inhibitors: Structural Characterization J.Med.Chem., 51, 2008

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