PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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8CUN	Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in 50% d6-DMSO and 50% water with cis/trans switching (CC conformation, 50%) 分子名称: Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-05-17 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
8CWA	Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in CDCl3 with cis/trans switching (TC conformation, 53%) 分子名称: Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-05-18 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
8JJS	Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... 著者 Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. 登録日 2023-05-31 公開日 2023-07-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.534 Å) 主引用文献 Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
7UBF	Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in 50% d6-DMSO and 50% water with cis/trans switching (CC conformation, 50%) 分子名称: Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-03-14 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
7UBI	Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in CDCl3 with cis/trans switching (TT conformation, 47%) 分子名称: Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-03-14 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
7UBE	Solution NMR structure of 8-residue Rosetta-designed cyclic peptide D8.21 in d6-DMSO with cis/trans switching 分子名称: Cyclic peptide D8.21 DVA-MLE-DPR-LEU-DVA-MLE-DPR-LEU 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-03-14 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
8SZQ	Cat DHX9 bound to ADP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. 登録日 2023-05-30 公開日 2023-08-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.711 Å) 主引用文献 Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
8SZP	Human DHX9 bound to ADP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, ... 著者 Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. 登録日 2023-05-30 公開日 2023-08-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
8SZR	Dog DHX9 bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNA helicase, ... 著者 Lee, Y.-T, Sickmier, E.A, Grigoriu, S, Boriack-Sjodin, P.A. 登録日 2023-05-30 公開日 2023-08-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Crystal structures of the DExH-box RNA helicase DHX9. Acta Crystallogr D Struct Biol, 79, 2023
7JRH	X-ray crystal structure of a cyclic peptide containing medin(19-25) and medin(31-37) 分子名称: CALCIUM ION, Cyclic peptide ASP-GLN-TRP-MLE-GLN-VAL-ASP-ORD-GLU-VAL-THR-GLY-ILE-ILE-THR-ORD 著者 Wierzbicki, M, Howitz, W.J, Nowick, J.S. 登録日 2020-08-12 公開日 2020-09-09 最終更新日 2020-09-30 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin 19-36 . J.Am.Chem.Soc., 142, 2020
5W5U	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141037 (P4) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-MLE-GLU-TYR-PHE-GLU-TRP-LEU-SER-BAL, ... 著者 Wilson, I.A, Kadam, R.U. 登録日 2017-06-15 公開日 2017-10-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.461 Å) 主引用文献 Potent peptidic fusion inhibitors of influenza virus. Science, 358, 2017
7UZL	Solution NMR structure of 9-residue Rosetta-designed cyclic peptide D9.16 in CDCl3 with cis/trans switching (B-TC conformation) 分子名称: Cyclic peptide D9.16 DPR-MAA-ALA-DVA-MLE-LEU-LEU-PRO-DLE 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-05-09 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
7UBC	Solution NMR structure of 9-residue Rosetta-designed cyclic peptide D9.16 in d6-DMSO with cis/trans switching 分子名称: Cyclic peptide D9.16 DPR-MAA-ALA-DVA-MLE-LEU-LEU-PRO-DLE 著者 Ramelot, T.A, Tejero, R, Monteltione, G.T. 登録日 2022-03-14 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
7UBG	Solution NMR structure of 9-residue Rosetta-designed cyclic peptide D9.16 in CDCl3 with cis/trans switching (A-TT conformation) 分子名称: Cyclic peptide D9.16 DPR-MAA-ALA-DVA-MLE-LEU-LEU-PRO-DLE 著者 Ramelot, T.A, Tejero, R, Montelione, G.T. 登録日 2022-03-14 公開日 2022-09-14 最終更新日 2022-09-28 実験手法 SOLUTION NMR 主引用文献 Accurate de novo design of membrane-traversing macrocycles. Cell, 185, 2022
3VEU	Crystal Structure of Human Beta Secretase in Complex with NVP-AVI326 分子名称: (2S)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(propan-2-yl)benzyl]amino}butan-2-yl]-2-[(5S)-6-oxo-1-propyl-1,7-diazaspiro[4.4]non-7-yl]propanamide, Beta-secretase 1 著者 Rondeau, J.M, Bourgier, E. 登録日 2012-01-09 公開日 2012-11-21 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Discovery of cyclic sulfone hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides J.Med.Chem., 55, 2012
1MVW	MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 分子名称: RABBIT SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL; LIGHT CHAIN, ... 著者 Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. 登録日 2002-09-26 公開日 2002-11-20 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (70 Å) 主引用文献 Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.STRUCT.BIOL., 138, 2002
8AV2	Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin receptor, SULFATE ION, ... 著者 Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. 登録日 2022-08-26 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
3QXX	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid 分子名称: 1,2-ETHANEDIOL, 8-aminooctanoic acid, Dethiobiotin synthetase, ... 著者 Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-02 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
3QXS	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ANP 分子名称: 1,2-ETHANEDIOL, Dethiobiotin synthetase, MAGNESIUM ION, ... 著者 Klimecka, M.M, Porebski, P.J, Chruszcz, M, Jablonska, K, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-02 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
3QXC	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ATP 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-01 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
3QXJ	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GTP 分子名称: 1,2-ETHANEDIOL, Dethiobiotin synthetase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Klimecka, M.M, Porebski, P.J, Chruszcz, M, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-01 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
3QY0	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP 分子名称: 1,2-ETHANEDIOL, Dethiobiotin synthetase, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-02 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
3QXH	Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ADP and 8-aminocaprylic acid 分子名称: 1,2-ETHANEDIOL, 8-aminooctanoic acid, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Minor, C, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) 登録日 2011-03-01 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
2IMQ	Crystal structure of ferrous cimex nitrophorin 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Salivary nitrophorin 著者 Weichsel, A, Montfort, W.R. 登録日 2006-10-04 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystallographic and spectroscopic characterization of ferrous complexes of cimex nitrophorin, a heme-thiolate protein from the bedbug To be Published
8UN5	KRAS-G13D-GDP in complex with Cpd38 ((E)-1-((3S)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one) 分子名称: (2E)-1-{(3S)-4-[(7M)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-{[(4R,7aS)-2-methylidenetetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-4-yl]-3-methylpiperazin-1-yl}-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one, GLYCEROL, GTPase KRas, ... 著者 Ultsch, M.H. 登録日 2023-10-18 公開日 2023-12-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors. Acs Med.Chem.Lett., 15, 2024

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