PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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6OBG	Ricin A chain bound to VHH antibody V8E6 分子名称: CHLORIDE ION, Ricin A chain, VHH antibody V8E6, ... 著者 Rudolph, M.J. 登録日 2019-03-20 公開日 2020-04-01 最終更新日 2020-10-14 実験手法 X-RAY DIFFRACTION (1.996 Å) 主引用文献 Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J.Mol.Biol., 432, 2020
7K3Q	An ultra-potent human neutralizing antibody locks the SARS-CoV-2 spike in the closed conformation 分子名称: 1,2-ETHANEDIOL, Fab fragment of S2E12 monoclonal antibody, heavy chain, ... 著者 Snell, G, Czudnochowski, N, Ng, C. 登録日 2020-09-12 公開日 2020-10-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020
4M5Z	Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit 分子名称: Fab 5J8 heavy chain, Fab 5J8 light chain, Hemagglutinin HA1 chain 著者 Hong, M, Lee, P.S, Wilson, I.A. 登録日 2013-08-08 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site. J.Virol., 87, 2013
6MPH	Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DF1W-a.01 Light chain, ... 著者 Acharya, P, Xu, K, Kwong, P.D. 登録日 2018-10-06 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6VJT	Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen 分子名称: Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein 著者 Oren, D.A, Nussenzweig, M.C, Wang, Q. 登録日 2020-01-17 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell Host Microbe, 28, 2020
6MPG	Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ... 著者 Acharya, P, Kwong, P.D. 登録日 2018-10-06 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
7MDT	BG505 SOSIP.v5.2 in complex with the monoclonal antibody Rh4O9.8 (as Fab fragment) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Rh4O9.8 monoclonal antibody Heavy Chain, ... 著者 Antanasijevic, A, Ozorowski, G, Nogal, B, Ward, A.B. 登録日 2021-04-06 公開日 2022-01-26 最終更新日 2022-02-02 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 From structure to sequence: Antibody discovery using cryoEM. Sci Adv, 8, 2022
7JUM	Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01 分子名称: Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv 著者 Tolia, N, Tang, W.K. 登録日 2020-08-20 公開日 2021-03-31 最終更新日 2021-04-07 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes. Nat Commun, 12, 2021
8F0G	Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1C3 Fab Heavy Chain, ... 著者 Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. 登録日 2022-11-02 公開日 2023-05-03 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence. Cell Rep, 42, 2023
7BWJ	crystal structure of SARS-CoV-2 antibody with RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... 著者 Wang, X, Ge, J. 登録日 2020-04-14 公開日 2020-06-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Human neutralizing antibodies elicited by SARS-CoV-2 infection. Nature, 584, 2020
5AWN	Crystal structure of Human anti-HIV-1 broadly neutralizing antibody 3BC176 Fab 分子名称: Heavy chain of 3BC176 Fab, Light chain of 3BC176 Fab 著者 Lee, J.H, Wilson, I.A, Ward, A.B. 登録日 2015-07-06 公開日 2015-11-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.887 Å) 主引用文献 Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun, 6, 2015
7UEN	Genetic and structural basis of the human anti-alpha-galactosyl antibody response 分子名称: M86 antibody Fab heavy chain, M86 antibody Fab light chain, PHOSPHATE ION, ... 著者 Langley, D.B, Christ, D. 登録日 2022-03-22 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7JKS	Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ... 著者 Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. 登録日 2020-07-28 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
7JKT	Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core from strain d45-01dG5, ... 著者 Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R. 登録日 2020-07-28 公開日 2021-06-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth. Immunity, 54, 2021
8DXU	Fab arms of antibodies GAR03 and 10G4 bound to the receptor binding domain of SARS-CoV-2 in a 1:1:1 complex. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of Fab arm of antibody 10G4, ... 著者 Langley, D.B, Christ, D. 登録日 2022-08-03 公開日 2023-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.728 Å) 主引用文献 Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients. Nat Commun, 14, 2023
7UEL	Genetic and structural basis for the human anti-alpha-galactosyl antibody response 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heavy chain Fab of antibody JEC1, ... 著者 Langley, D.B, Christ, D. 登録日 2022-03-22 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7UEM	Genomic and structural basis for the human anti-alpha-galactosyl antibody response 分子名称: CHLORIDE ION, Heavy chain Fab arm of antibody HKB7, Light chain Fab of antibody HKB7, ... 著者 Langley, D.B, Christ, D. 登録日 2022-03-22 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.314 Å) 主引用文献 Genetic and structural basis of the human anti-alpha-galactosyl antibody response. Proc.Natl.Acad.Sci.USA, 119, 2022
7LRT	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 spike glycoprotein, ... 著者 Zhou, T, Tsybovsky, T. 登録日 2021-02-17 公開日 2021-07-14 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
7U0D	Local refinement of cryo-EM structure of the interface of the Omicron RBD in complex with antibodies B-182.1 and A19-46.1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 antibody A19-46.1, Heavy chain of SARS-CoV-2 antibody B1-182.1, ... 著者 Zhou, T, kwong, P.D. 登録日 2022-02-17 公開日 2022-03-30 最終更新日 2022-10-19 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529. Science, 376, 2022
5TOK	Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... 著者 Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. 登録日 2016-10-17 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
5TOJ	Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... 著者 Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. 登録日 2016-10-17 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
7KKZ	Crystal structure of mouse anti-HIV potent neutralizing antibody M4H2K1 分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Heavy chain of Fab fragment of mouse monoclonal antibody M4H2K1, ... 著者 Kumar, S, Wilson, I.A. 登録日 2020-10-28 公開日 2021-07-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles. Mbio, 12, 2021
8C0Y	SARS-CoV2 Omicron BA.1 RBD in complex with CAB-A17 antibody 分子名称: CAB-A17 antibody (variable), Spike protein S2' 著者 Das, H, Hallberg, B.M. 登録日 2022-12-19 公開日 2024-06-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.68 Å) 主引用文献 Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies. Cell Rep Med, 5, 2024
7FCQ	Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, P14-44 antibody Fab fragment heavy chain, ... 著者 Zheng, P, Jin, T. 登録日 2021-07-15 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance. J.Clin.Invest., 132, 2022
7LUE	Prefusion RSV F glycoprotein bound by neutralizing site V-directed antibody ADI-14442 分子名称: Fusion glycoprotein F0, Heavy chain of human antibody Fab ADI-14442, Light chain of human antibody Fab ADI-14442 著者 Gilman, M.S.A, McLellan, J.S. 登録日 2021-02-22 公開日 2021-06-16 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021

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