7E2H
 
 | | Cryo-EM structure of hDisp1NNN-3C-Cleavage | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1 | | 著者 | Li, W, Wang, L, Gong, X. | | 登録日 | 2021-02-05 | | 公開日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release.
Nat Commun, 12, 2021
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8IO3
 | | Cryo-EM structure of human HCN3 channel with cilobradine | | 分子名称: | 3-[[(3~{S})-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1~{H}-3-benzazepin-4-one, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 | | 著者 | Yu, B, Lu, Q.Y, Li, J, Zhang, J. | | 登録日 | 2023-03-10 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Cryo-EM structure of human HCN3 channel with cilobradine
To Be Published
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5C51
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | 分子名称: | DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y. | | 登録日 | 2015-06-19 | | 公開日 | 2016-05-11 | | 最終更新日 | 2016-05-18 | | 実験手法 | X-RAY DIFFRACTION (3.426 Å) | | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5C52
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | 分子名称: | DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | | 登録日 | 2015-06-19 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.637 Å) | | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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5C53
 | | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | | 分子名称: | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | | 登録日 | 2015-06-19 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.567 Å) | | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
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7V3Z
 | | Structure of cannabinoid receptor type 1(CB1) | | 分子名称: | 2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol, CHOLESTEROL, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Liu, Z.J, Shen, L, Hua, T, Yao, D.Q, Wu, L.J. | | 登録日 | 2021-08-12 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | A Genetically Encoded F-19 NMR Probe Reveals the Allosteric Modulation Mechanism of Cannabinoid Receptor 1.
J.Am.Chem.Soc., 143, 2021
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7XB0
 | | Crystal structure of Omicron BA.2 RBD complexed with hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Li, L, Liao, H, Meng, Y, Li, W. | | 登録日 | 2022-03-19 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
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7XAZ
 | | Crystal structure of Omicron BA.1.1 RBD complexed with hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Liao, H, Meng, Y, Li, W. | | 登録日 | 2022-03-19 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
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7XCP
 | | Cryo-EM structure of Omicron RBD complexed with ACE2 and 304 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 304 Fab, ... | | 著者 | Zhao, Z, Qi, J, Gao, F.G. | | 登録日 | 2022-03-24 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Nat Commun, 13, 2022
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7XB1
 | | Crystal structure of Omicron BA.3 RBD complexed with hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Li, W, Meng, Y, Liao, H. | | 登録日 | 2022-03-19 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.
Cell, 185, 2022
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6RAS
 | | Pmar-Lig_Pre. | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent DNA ligase, DNA, ... | | 著者 | Leiros, H.K.S, Williamson, A. | | 登録日 | 2019-04-07 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Nucleic Acids Res., 47, 2019
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6RAU
 | | PostS3_Pmar_lig4_WT | | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent DNA ligase, DNA (5'-D(*AP*TP*TP*GP*CP*GP*AP*CP*CP*CP*CP*AP*CP*TP*AP*TP*CP*GP*GP*AP*A)-3'), ... | | 著者 | Leiros, H.K.S, Williamson, A. | | 登録日 | 2019-04-08 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural intermediates of a DNA-ligase complex illuminate the role of the catalytic metal ion and mechanism of phosphodiester bond formation.
Nucleic Acids Res., 47, 2019
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6MKS
 | | Cryo-EM structure of NLRC4-CARD filament | | 分子名称: | Chimera protein of NLR family CARD domain-containing protein 4 and EGFP | | 著者 | Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H. | | 登録日 | 2018-09-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
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7U8G
 | | Cryo-EM structure of the core human NADPH oxidase NOX2 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ... | | 著者 | Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T. | | 登録日 | 2022-03-08 | | 公開日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the core human NADPH oxidase NOX2.
Nat Commun, 13, 2022
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7FBV
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7FBR
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8HCO
 | | Substrate-engaged TOM complex from yeast | | 分子名称: | Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, Mitochondrial import receptor subunit TOM5, ... | | 著者 | Zhou, X.Y, Yang, Y.Q, Wang, G.P, Wang, S.S. | | 登録日 | 2022-11-02 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Molecular pathway of mitochondrial preprotein import through the TOM-TIM23 supercomplex.
Nat.Struct.Mol.Biol., 30, 2023
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8U1U
 | | Structure of a class A GPCR/agonist complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Sun, D, Johnson, M, Masureel, M. | | 登録日 | 2023-09-02 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
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6LR2
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8CPX
 | | Human apoferritin after 488 nm laser exposure in presence of rsEGFP2 | | 分子名称: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | 著者 | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | 登録日 | 2023-03-03 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (1.76 Å) | | 主引用文献 | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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8CPW
 | | Human apoferritin after 405 nm + 488 nm laser exposure in presence of rsEGFP2 | | 分子名称: | Ferritin heavy chain, N-terminally processed, MAGNESIUM ION, ... | | 著者 | Last, M.G.F, Noteborn, W.E.M, Sharp, T.H. | | 登録日 | 2023-03-03 | | 公開日 | 2023-03-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (1.79 Å) | | 主引用文献 | Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM.
J.Struct.Biol., 215, 2023
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4TS2
 | | Crystal structure of the Spinach RNA aptamer in complex with DFHBI, magnesium ions | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R. | | 登録日 | 2014-06-18 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.884 Å) | | 主引用文献 | Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.
Nat.Struct.Mol.Biol., 21, 2014
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4TS0
 | | Crystal structure of the Spinach RNA aptamer in complex with DFHBI, barium ions | | 分子名称: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, BARIUM ION, POTASSIUM ION, ... | | 著者 | Warner, K.D, Chen, M.C, Song, W, Strack, R.L, Thorn, A, Jaffrey, S.R, Ferre-D'Amare, A.R. | | 登録日 | 2014-06-18 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for activity of highly efficient RNA mimics of green fluorescent protein.
Nat.Struct.Mol.Biol., 21, 2014
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5WWK
 | | Highly stable green fluorescent protein | | 分子名称: | Green fluorescent protein | | 著者 | Sriram, R, George, A, Kesavan, M, Jaimohan, S.M, Kamini, N.R, Easwaramoorthi, S, Ganesh, S, Gunasekaran, K, Ayyadurai, N. | | 登録日 | 2017-01-02 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.199 Å) | | 主引用文献 | Excited State Electronic Interconversion and Structural Transformation of Engineered Red-Emitting Green Fluorescent Protein Mutant.
J.Phys.Chem.B, 123, 2019
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3AI5
 | | Crystal structure of yeast enhanced green fluorescent protein-ubiquitin fusion protein | | 分子名称: | 1,2-ETHANEDIOL, yeast enhanced green fluorescent protein,Ubiquitin | | 著者 | Suzuki, N, Wakatsuki, S, Kawasaki, M. | | 登録日 | 2010-05-10 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystallization of small proteins assisted by green fluorescent protein
Acta Crystallogr.,Sect.D, 66, 2010
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