PDB: 2729 件ウェブページステータス検索Chemie searchBIRD

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8FV8	E coli. CTP synthase in complex with dF-dCTP + ADP 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-DIPHOSPHATE, CTP synthase, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVA	E coli. CTP synthase in complex with F-araCTP 分子名称: 4-amino-1-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CTP synthase, MALONIC ACID, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV9	E coli. CTP synthase in complex with F-dCTP 分子名称: 2'-deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVB	E coli. CTP synthase in complex with CTP 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVE	E coli. CTP synthase in complex with CTP (potassium malonate + 100 mM MgCl2) 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVD	E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 100 mM MgCl2) 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MAGNESIUM ION, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVC	E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 5 mM MgCl2) 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
7VKV	NMR structure of the zeta-subunit of the F1F0-ATPase from Sinorhizobium meliloti 分子名称: zeta-subunit 著者 Yang, L.Y, Mendoza-Hoffmann, F, Buratto, D. 登録日 2021-10-01 公開日 2021-10-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Inhibitory to non-inhibitory evolution of the zeta subunit of the F 1 F O -ATPase of Paracoccus denitrificans and alpha-proteobacteria as related to mitochondrial endosymbiosis. Front Mol Biosci, 10, 2023
5TET	TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate 分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-22 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TDZ	TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-20 公開日 2017-08-09 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TES	TEV Cleaved Human ATP Citrate Lyase Bound to Citrate and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-22 公開日 2017-08-09 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TDF	TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate 分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TDM	TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP 分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2025-04-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TE1	C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate 分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-20 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
2E89	Crystal structure of Aquifex aeolicus TilS in a complex with ATP, Magnesium ion, and L-lysine 分子名称: ADENOSINE-5'-TRIPHOSPHATE, LYSINE, MAGNESIUM ION, ... 著者 Kuratani, M, Yoshikawa, Y, Takahashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-01-19 公開日 2007-11-13 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine To be Published
9FNN	Cryo-EM structure of the c-di-GMP-saturated 'crown'less Bcs macrocomplex for cellulose secretion in E. coli 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-5'-TRIPHOSPHATE, Cell division protein, ... 著者 Anso, I, Krasteva, P.V. 登録日 2024-06-10 公開日 2024-10-16 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Structural basis for synthase activation and cellulose modification in the E. coli Type II Bcs secretion system. Nat Commun, 15, 2024
9FP0	Cryo-EM structure of the 'crown'less Bcs macrocomplex for E. coli cellulose secretion in non-saturating c-di-GMP (local) 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ADENOSINE-5'-TRIPHOSPHATE, Cell division protein, ... 著者 Anso, I, Krasteva, P.V. 登録日 2024-06-12 公開日 2024-10-16 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Structural basis for synthase activation and cellulose modification in the E. coli Type II Bcs secretion system. Nat Commun, 15, 2024
3LZE	Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS), E37C catalytic residue mutant 分子名称: PTERINE, Putative 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION 著者 Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2010-03-01 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published
3M0N	Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS), E37A catalytic residue mutant 分子名称: PTERINE, Putative 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION 著者 Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2010-03-03 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published
3TSY	4-Coumaroyl-CoA Ligase::Stilbene Synthase fusion protein 分子名称: Fusion Protein 4-coumarate--CoA ligase 1, Resveratrol synthase 著者 Yi, H, Jez, J.M. 登録日 2011-09-13 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and Kinetic Analysis of the Unnatural Fusion Protein 4-Coumaroyl-CoA Ligase::Stilbene Synthase. J.Am.Chem.Soc., 133, 2011
3LX3	Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin 分子名称: 2-amino-1,5-dihydropteridine-4,6-dione, 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION 著者 Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2010-02-24 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published
7MO6	Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293 分子名称: GMP synthase [glutamine-hydrolyzing] 著者 Nguyen, S, Bruning, J.B. 登録日 2021-05-01 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta Crystallogr D Struct Biol, 78, 2022
1DV2	The structure of biotin carboxylase, mutant E288K, complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE 著者 Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. 登録日 2000-01-19 公開日 2000-06-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
2OBL	Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria 分子名称: ACETATE ION, CALCIUM ION, EscN, ... 著者 Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J. 登録日 2006-12-19 公開日 2007-01-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural analysis of a prototypical ATPase from the type III secretion system. Nat.Struct.Mol.Biol., 14, 2007
2OBM	Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, EscN 著者 Zarivach, R, Vuckovic, M, Deng, W, Finlay, B.B, Strynadka, N.C.J. 登録日 2006-12-19 公開日 2007-01-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural analysis of a prototypical ATPase from the type III secretion system. Nat.Struct.Mol.Biol., 14, 2007

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