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6TDA
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BU of 6tda by Molmil
Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome
分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC58, ...
著者Wagner, F.R, Dienemann, C, Wang, H, Stuetzer, A, Tegunov, D, Urlaub, H, Cramer, P.
登録日2019-11-08
公開日2020-03-18
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome.
Nature, 579, 2020
3SCZ
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BU of 3scz by Molmil
Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase
分子名称: HYPOXANTHINE, Purine nucleoside phosphorylase
著者de Azevedo Jr, W.F, Caceres, R.A, Timmers, L.F.S.M, Ducati, R.G, Rosado, L.A, Basso, L.A, Santos, D.S.
登録日2011-06-08
公開日2012-06-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Combining crystallographic, thermodynamic, and molecular dynamics studies of Mycobacterium tuberculosis purine nucleoside phosphorylase
To be Published
1YRY
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BU of 1yry by Molmil
Crystal structure of human PNP complexed with MESG
分子名称: 7-METHYL-6-THIO-GUANOSINE, Purine nucleoside phosphorylase, SULFATE ION
著者Silva, R.G, Pereira, J.H, Canduri, F, Basso, L.A, de Azevedo Jr, W.F, Santos, D.S.
登録日2005-02-05
公開日2006-01-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
Arch.Biochem.Biophys., 442, 2005
6JR1
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BU of 6jr1 by Molmil
Crystal structure of the human nucleosome phased with 16 selenium atoms
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W.
登録日2019-04-02
公開日2019-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure determination of the nucleosome core particle by selenium SAD phasing.
Acta Crystallogr D Struct Biol, 75, 2019
6JR0
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BU of 6jr0 by Molmil
Crystal structure of the human nucleosome phased with 12 selenium atoms
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W.
登録日2019-04-02
公開日2019-10-02
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure determination of the nucleosome core particle by selenium SAD phasing.
Acta Crystallogr D Struct Biol, 75, 2019
8YNY
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BU of 8yny by Molmil
Structure of Cas9-sgRNA ribonucleoprotein bound to nucleosome
分子名称: CRISPR-associated endonuclease Cas9/Csn1, DNA (17-mer), DNA (175-mer), ...
著者Nagamura, R, Kujirai, T, Kusakizako, T, Hirano, H, Kurumizaka, H, Nureki, O.
登録日2024-03-12
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Structural insights into how Cas9 targets nucleosomes.
Nat Commun, 15, 2024
5B2J
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BU of 5b2j by Molmil
Human nucleosome containing CpG methylated DNA
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S.
登録日2016-01-18
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
5T3K
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BU of 5t3k by Molmil
Fluorescence detection of RNA-ligand binding and crystal structure determination of ribosomal decoding site RNA using a heavy atom containing fluorescent ribonucleoside
分子名称: MAGNESIUM ION, RNA (5'-R(*CP*AP*GP*CP*GP*(75B)P*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*UP*GP*G)-3')
著者Hermann, T, Boerneke, M.A.
登録日2016-08-25
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.142 Å)
主引用文献Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe.
Angew. Chem. Int. Ed. Engl., 56, 2017
8XJV
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BU of 8xjv by Molmil
Structural basis for the linker histone H5-nucleosome binding and chromatin compaction
分子名称: DNA, Histone H2A, Histone H2B 1.1, ...
著者Li, W.Y, Song, F, Zhu, P.
登録日2023-12-22
公開日2024-09-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction.
Cell Res., 34, 2024
9J0P
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BU of 9j0p by Molmil
Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC2-nuc)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Naganuma, M, Kujirai, T, Ehara, H, Uejima, T, Ito, T, Goto, M, Aoki, M, Henmi, M, Miyamoto-Kohno, S, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2024-08-02
公開日2025-02-05
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome.
Sci Adv, 11, 2025
9J0N
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BU of 9j0n by Molmil
Paused elongation complex of mammalian RNA polymerase II with nucleosome (PEC2-nuc)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Naganuma, M, Kujirai, T, Ehara, H, Uejima, T, Ito, T, Goto, M, Aoki, M, Henmi, M, Miyamoto-Kohno, S, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2024-08-02
公開日2025-02-05
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome.
Sci Adv, 11, 2025
9J0O
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BU of 9j0o by Molmil
Arrested elongation complex of mammalian RNA polymerase II with nucleosome (AEC1-nuc)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Naganuma, M, Kujirai, T, Ehara, H, Uejima, T, Ito, T, Goto, M, Aoki, M, Henmi, M, Miyamoto-Kohno, S, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2024-08-02
公開日2025-02-05
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into promoter-proximal pausing of RNA polymerase II at +1 nucleosome.
Sci Adv, 11, 2025
6JOU
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BU of 6jou by Molmil
Crystal structure of the human nucleosome containing H2A.Z.1 S42R
分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
著者Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H.
登録日2019-03-23
公開日2020-03-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo.
Biochem.Biophys.Res.Commun., 515, 2019
5B2I
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BU of 5b2i by Molmil
Human nucleosome containing CpG unmethylated DNA
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S.
登録日2016-01-16
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
8HXY
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BU of 8hxy by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
6T90
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BU of 6t90 by Molmil
OCT4-SOX2-bound nucleosome - SHL-6
分子名称: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ...
著者Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-10-25
公開日2020-05-06
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
1YVX
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BU of 1yvx by Molmil
Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor
分子名称: 3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION
著者Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G.
登録日2005-02-16
公開日2005-03-22
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
9GD3
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BU of 9gd3 by Molmil
Structure of a mononucleosome bound by one copy of Chd1 with the DBD on the exit-side DNA.
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
著者Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
登録日2024-08-04
公開日2024-09-18
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
8V7L
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BU of 8v7l by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-12-04
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8GXQ
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BU of 8gxq by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y.
登録日2022-09-21
公開日2022-11-02
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (5.04 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
8GXS
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BU of 8gxs by Molmil
PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X.
登録日2022-09-21
公開日2022-11-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
1SQ6
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BU of 1sq6 by Molmil
Plasmodium falciparum homolog of Uridine phosphorylase/Purine nucleoside phosphorylase
分子名称: SULFATE ION, uridine phosphorylase, putative
著者Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-03-17
公開日2004-04-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
Acta Crystallogr.,Sect.D, 61, 2005
5TBV
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BU of 5tbv by Molmil
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with tubercidin
分子名称: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase, ...
著者Faheem, M, Torini, J.R, Romanello, L, Brandao-Neto, J, Pereira, H.M.
登録日2016-09-13
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase
To Be Published
9J8O
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BU of 9j8o by Molmil
Cryo-EM structure of BAF-Lamin A/C IgF-H1-nucleosome complex
分子名称: Barrier-to-autointegration factor, DNA (193-MER), Histone H1.1, ...
著者Horikoshi, N, Miyake, R, Sogawa-Fujiwara, C, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-08-21
公開日2025-02-26
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Cryo-EM structures of the BAF-Lamin A/C complex bound to nucleosomes.
Nat Commun, 16, 2025
9J8N
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BU of 9j8n by Molmil
Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (Low mobility complex)
分子名称: Barrier-to-autointegration factor, DNA (193-MER), Histone H2A type 1-B/E, ...
著者Horikoshi, N, Miyake, R, Sogawa-Fujiwara, C, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-08-21
公開日2025-02-26
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (7.14 Å)
主引用文献Cryo-EM structures of the BAF-Lamin A/C complex bound to nucleosomes.
Nat Commun, 16, 2025

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件を2025-07-09に公開中

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