PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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6QMO	Death-associated Protein Kinase 1 (DAPK1) catalytic and auto-regulatory domains with S289E and S308A mutations 分子名称: CHLORIDE ION, Death-associated protein kinase 1, GLYCEROL, ... 著者 Huart, A.-S, Wilmanns, M. 登録日 2019-02-07 公開日 2019-08-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Molecular mechanisms behind DAPK regulation: how phosphorylation switches work To Be Published
6QN6	Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide 分子名称: Carbonic anhydrase 9, ZINC ION, ~{N}-butyl-4-chloranyl-2-(2-phenylethylsulfanyl)-5-sulfamoyl-benzamide 著者 Leitans, J, Tars, K. 登録日 2019-02-09 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur.J.Med.Chem., 185, 2020
5L6Y	il13 in complex with tralokinumab 分子名称: FORMIC ACID, Interleukin-13, tralokinumab FAb digest VH, ... 著者 Breed, J. 登録日 2016-06-01 公開日 2016-12-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2. J. Mol. Biol., 429, 2017
5L8F	Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant E32A, E62A, H65A. 分子名称: MAGNESIUM ION, Rru_A0973, TRIETHYLENE GLYCOL 著者 He, D, Hughes, S, Vanden-Hehir, S, Georgiev, A, Altenbach, K, Tarrant, E, Mackay, C.L, Waldron, K.J, Clarke, D.J, Marles-Wright, J. 登録日 2016-06-07 公開日 2017-06-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.247 Å) 主引用文献 Crystal structure of Rhodospirillum rubrum Rru_A0973 mutant E32A, E62A, H65A. To be published
6QNM	Apo state of chemotaxis sensor ODP from T. denticola 分子名称: OXYGEN-BINDING DI-IRON PROTEIN 著者 Muok, A.R, Chong, J.E, Crane, B.R. 登録日 2019-02-11 公開日 2019-06-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A di-iron protein recruited as an Fe[II] and oxygen sensor for bacterial chemotaxis functions by stabilizing an iron-peroxy species. Proc.Natl.Acad.Sci.USA, 116, 2019
4UFL	Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. 登録日 2015-03-17 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6, 2015
6QY9	Human CSNK2A2 bound to a Pyrrolo[2,3-d]pyrimidinyl inhibitor 分子名称: 1,2-ETHANEDIOL, 3-[3-[2-[(3,4,5-trimethoxyphenyl)amino]pyrrolo[2,3-d]pyrimidin-7-yl]phenyl]propanenitrile, CHLORIDE ION, ... 著者 Abdul Azeez, K.R, Sorrell, F.J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M. 登録日 2019-03-08 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Human CSNK2A2 bound to a Pyrrolo[2,3-d]pyrimidinyl inhibitor To Be Published
6QYG	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 8.5 with Mg2+ and CoA. 分子名称: COENZYME A, MAGNESIUM ION, Possible 4'-phosphopantetheinyl transferase 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-08 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
4W9J	pVHL:EloB:EloC in complex with (2S,4R)-1-((S)-2-((S)-2-acetamido-4-methylpentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 13) 分子名称: N-acetyl-L-leucyl-3-methyl-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Gadd, M.S, Galdeano, C, van Molle, I, Ciulli, A. 登録日 2014-08-27 公開日 2014-09-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities. J.Med.Chem., 57, 2014
5L9U	Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination 分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ... 著者 Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A. 登録日 2016-06-11 公開日 2016-09-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
6QYQ	Crystal structure of human thymidylate synthase (hTS) variant R175C 分子名称: CHLORIDE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... 著者 Pozzi, C, Mangani, M. 登録日 2019-03-09 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors. Molecules, 24, 2019
6QYY	The crystal structure of head fiber gp8.5 N base in bacteriophage phi29 分子名称: Capsid fiber protein, SULFATE ION 著者 Xu, J, Wang, D, Gui, M, Xiang, Y. 登録日 2019-03-10 公開日 2019-06-12 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural assembly of the tailed bacteriophage φ29. Nat Commun, 10, 2019
4WBE	Crystal structure of the HR-1 domain of human caprin-1 in the C121 space group 分子名称: Caprin-1 著者 Wu, Y, Zhu, J, Huang, X, Du, Z. 登録日 2014-09-03 公開日 2015-10-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the HR-1 domain of human caprin-1 in the C121 space group To be published
4WBT	Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Shabalin, I.G, Bacal, P, Kowalska, A.K, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2014-09-03 公開日 2014-09-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of histidinol-phosphate aminotransferase from Sinorhizobium meliloti in complex with pyridoxal-5'-phosphate to be published
4WCL	Crystal Structure of product bound Cell Shape Determinant protein Csd4 from Helicobacter pylori 分子名称: 2,6-DIAMINOPIMELIC ACID, Conserved hypothetical secreted protein, IODIDE ION, ... 著者 Chan, A.C, Murphy, M.E. 登録日 2014-09-05 公開日 2014-12-24 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. J.Biol.Chem., 290, 2015
6QZR	14-3-3 sigma in complex with FOXO1 pT24 peptide 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Forkhead box protein O1, ... 著者 Ottmann, C, Wolter, M, Lau, R.A. 登録日 2019-03-12 公開日 2019-07-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294, 2019
5KVJ	Crystal structure of the 16-mer doublestranded RNA. Northeast Structural Genomics Consortium (NESG) target RNA1 分子名称: ARGININE, RNA (5'-R(P*CP*CP*AP*UP*CP*CP*UP*CP*UP*AP*CP*AP*GP*GP*CP*G)-3'), RNA (5'-R(P*CP*GP*CP*CP*UP*GP*UP*AP*GP*AP*GP*GP*AP*UP*GP*G)-3') 著者 Vorobiev, S.M, Ma, L.-C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2016-07-14 公開日 2016-08-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.261 Å) 主引用文献 Crystal structure of the 16-mer double stranded RNA. To be published
7C6A	Crystal structure of AT2R-BRIL and SRP2070_Fab complex 分子名称: IgG Light Chain, IgG heavy chain, SAR1, ... 著者 Suzuki, M, Miyagi, H, Asada, H, Yasunaga, M, Suno, C, Takahashi, Y, Saito, J, Iwata, S. 登録日 2020-05-21 公開日 2020-07-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 The discovery of a new antibody for BRIL-fused GPCR structure determination. Sci Rep, 10, 2020
6QWS	Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum in the apo state 分子名称: Pre-mRNA splicing helicase-like protein, SULFATE ION 著者 Absmeier, E, Santos, K.F, Wahl, M.C. 登録日 2019-03-06 公開日 2020-01-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
5KWN	The WD domain ofArabidopsis thaliana E3 Ubiquitin Ligase COP1 in complex with peptide from HY5 分子名称: E3 ubiquitin-protein ligase COP1, peptide 16-mer 著者 Uljon, S, Blacklow, S. 登録日 2016-07-18 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The COP1 WD domain in complex with HY5 peptide To Be Published
4UNW	Structure of the A_Equine_Newmarket_2_93 H3 haemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Vachieri, S.G, Collins, P.J, Haire, L.F, Ogrodowicz, R.W, Martin, S.R, Walker, P.A, Xiong, X, Gamblin, S.J, Skehel, J.J. 登録日 2014-05-31 公開日 2014-07-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Recent Evolution of Equine Influenza and the Origin of Canine Influenza. Proc.Natl.Acad.Sci.USA, 111, 2014
6QY7	Human CSNK2A1 bound to ERB-041 分子名称: 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL, CHLORIDE ION, Casein kinase II subunit alpha 著者 Abdul Azeez, K.R, Sorrell, F.J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M. 登録日 2019-03-08 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 CSNK2A1 bound to ERB-041 To Be Published
6QYF	4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus at pH 4.6 with Mg2+ and CoA. 分子名称: COENZYME A, MAGNESIUM ION, Possible 4'-phosphopantetheinyl transferase 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-03-08 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
6QY8	Human CSNK2A2 bound to ERB-041 分子名称: 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL, Casein kinase II subunit alpha' 著者 Abdul Azeez, K.R, Sorrell, F.J, Krojer, T, Bountra, C, Edwards, A.M, Arrowsmith, C, Knapp, S, Elkins, J.M. 登録日 2019-03-08 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 CSNK2A1 bound to ERB-041 To Be Published
5L0P	Symmetry-based assembly of a two-dimensional protein lattice 分子名称: Transcription factor ETV6, Ferric uptake regulation protein chimera 著者 Faham, S. 登録日 2016-07-27 公開日 2017-03-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Symmetry based assembly of a 2 dimensional protein lattice. PLoS ONE, 12, 2017

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