PDB: 23413 件ウェブページステータス検索Chemie searchBIRD

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2KGA	NMR Solution Structures of hexanoyl ACP (a non natural intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor 分子名称: Actinorhodin polyketide synthase acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate 著者 Crump, M.P, Evans, S.E, Williams, C. 登録日 2009-03-07 公開日 2009-04-14 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
1HVB	CRYSTAL STRUCTURE OF STREPTOMYCES R61 DD-PEPTIDASE COMPLEXED WITH A NOVEL CEPHALOSPORIN ANALOG OF CELL WALL PEPTIDOGLYCAN 分子名称: 5-{3-(S)-(4-(R)-ACETYLAMINO-4-CARBOXY-BUTYRYLAMINO)-3-[1-(R)-(1-(R)-CARBOXY-ETHYLCARBAMOYL)-ETHYLCARBAMOYL]-PROPYL}-2-( CARBOXY-PHENYLACETYLAMINO-METHYL)-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE 著者 McDonough, M.A, Lee, W, Silvaggi, N.R, Mobashery, S, Kelly, J.A. 登録日 2001-01-08 公開日 2001-02-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis. Proc.Natl.Acad.Sci.USA, 98, 2001
8JNC	Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-maltophilin 分子名称: (1Z,3E,5S,8R,9S,10S,11R,13R,15R,16S,18Z,24S,25S)-11-ethyl-2,24-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-7,20,27,28-tetraone, Cytochrome P450, FORMIC ACID, ... 著者 Zhang, Y.L, Zhang, L.P, Zhang, C.S. 登録日 2023-06-06 公開日 2023-11-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
8JNO	Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-deOH-HSAF 分子名称: (1Z,3E,5S,7S,8R,9S,10S,11R,13R,15R,16S,18Z,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhang, Y.L, Zhang, L.P, Zhang, C.S. 登録日 2023-06-06 公開日 2023-11-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
3OII	Crystal structure of Saccharomyces Cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine 分子名称: Essential for mitotic growth 1, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE 著者 Thomas, S.R, Szyk, A, LaRonde-LeBlanc, N. 登録日 2010-08-19 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res., 39, 2011
3MNM	Crystal structure of GAE domain of GGA2p from Saccharomyces cerevisiae 分子名称: ADP-ribosylation factor-binding protein GGA2, GLYCEROL, SULFATE ION 著者 Fang, P, Wang, J, Li, X, Niu, L, Teng, M. 登録日 2010-04-21 公開日 2010-09-08 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural basis for the specificity of the GAE domain of yGGA2 for its accessory proteins Ent3 and Ent5 Biochemistry, 49, 2010
1PWD	Covalent acyl enzyme complex of the Streptomyces R61 DD-peptidase with cephalosporin C 分子名称: (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase precursor 著者 Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. 登録日 2003-07-01 公開日 2004-07-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
1PW1	Non-Covalent Complex Of Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin 分子名称: (2S,5R,6R)-6-{[(6R)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, D-alanyl-D-alanine carboxypeptidase, FORMYL GROUP, ... 著者 Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. 登録日 2003-06-30 公開日 2004-07-13 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
2NZ5	Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2) 分子名称: Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE, naphthalene-1,2,4,5,7-pentol 著者 Zhao, B, Lamb, D.C, Kelly, S.L, Waterman, M.R. 登録日 2006-11-22 公開日 2007-07-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2. Biochemistry, 46, 2007
6UCU	Cryo-EM structure of the mitochondrial TOM complex from yeast (dimer) 分子名称: DODECYL-BETA-D-MALTOSIDE, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... 著者 Park, E, Tucker, K. 登録日 2019-09-17 公開日 2019-11-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution. Nat.Struct.Mol.Biol., 26, 2019
6R86	Yeast Vms1-60S ribosomal subunit complex (post-state) 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. 登録日 2019-03-31 公開日 2019-07-31 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
6Q8Y	Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2018-12-16 公開日 2019-03-13 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the 80S ribosome-Xrn1 nuclease complex. Nat.Struct.Mol.Biol., 26, 2019
6R87	Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1) 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. 登録日 2019-03-31 公開日 2019-06-26 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
6GZW	Ferric DtpA from Streptomyces lividans 分子名称: Dye type peroxidase A, PROTOPORPHYRIN IX CONTAINING FE 著者 Moreno Chicano, T, Worrall, J.A.R, Hough, M.A. 登録日 2018-07-05 公開日 2019-05-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis. Chemistry, 25, 2019
1N4U	CHOLESTEROL OXIDASE FROM STREPTOMYCES @ pH 4.5 (STREPTOMYCES SP. SA-COO) 分子名称: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Vrielink, A, Lario, P.I. 登録日 2002-11-01 公開日 2004-04-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment Nat.Chem.Biol., 2, 2006
1CG7	HMG PROTEIN NHP6A FROM SACCHAROMYCES CEREVISIAE 分子名称: PROTEIN (NON HISTONE PROTEIN 6 A) 著者 Allain, F.H.T, Yen, Y.M, Masse, J.E, Schultze, P, Dieckmann, T, Johnson, R.C, Feigon, J. 登録日 1999-03-27 公開日 1999-10-14 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding. EMBO J., 18, 1999
7ZSB	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZSA	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2022-05-06 公開日 2022-11-16 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
6R84	Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. 登録日 2019-03-31 公開日 2019-06-26 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
7DXO	The mutant of bifunctional thioesterase catalyzing epimerization and cyclization 分子名称: Non-ribosomal peptide synthetase 4 著者 Yu, J.H, Song, J, Chi, C.B, Ma, M. 登録日 2021-01-19 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Functional Characterization and Crystal Structure of the Bifunctional Thioesterase Catalyzing Epimerization and Cyclization in Skyllamycin Biosynthesis Acs Catalysis, 11, 2021
1PWG	Covalent Penicilloyl Acyl Enzyme Complex Of The Streptomyces R61 DD-Peptidase With A Highly Specific Penicillin 分子名称: (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, D-alanyl-D-alanine carboxypeptidase 著者 Silvaggi, N.R, Josephine, H.R, Pratt, R.F, Kelly, J.A. 登録日 2003-07-01 公開日 2004-07-13 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.074 Å) 主引用文献 Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin" J.Mol.Biol., 345, 2005
8AIP	Crystal Structure of Two-domain bacterial laccase from the actinobacterium Streptomyces carpinensis VKM Ac-1300 分子名称: COPPER (II) ION, OXYGEN MOLECULE, Two-Domain Laccase 著者 Gabdulkhakov, A.G, Tishchenko, T.V, Trubitsina, L, Trubitsin, I, Leontievsky, A, Lisov, A. 登録日 2022-07-27 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A Novel Two-Domain Laccase with Middle Redox Potential: Physicochemical and Structural Properties. Biochemistry Mosc., 88, 2023
5MJS	S. pombe microtubule copolymerized with GTP and Mal3-143 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Microtubule integrity protein mal3, ... 著者 von Loeffelholz, O, Moores, C. 登録日 2016-12-01 公開日 2017-12-20 最終更新日 2025-03-19 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics. Nat Commun, 8, 2017
1IKG	MICHAELIS COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT 分子名称: D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANYL-D-ALANINE 著者 Mcdonough, M.A, Anderson, J.W, Silvaggi, N.R, Pratt, R.F, Knox, J.R, Kelly, J.A. 登録日 2001-05-03 公開日 2002-09-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins. J.Mol.Biol., 322, 2002
6UCV	Cryo-EM structure of the mitochondrial TOM complex from yeast (tetramer) 分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... 著者 Park, E, Tucker, K. 登録日 2019-09-17 公開日 2019-11-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution. Nat.Struct.Mol.Biol., 26, 2019

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