8Q6S
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![BU of 8q6s by Molmil](/molmil-images/mine/8q6s) | A carbohydrate esterase family 15 (CE15) glucuronoyl esterase from Phocaeicola vulgatus ATCC 8482 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Putative acetyl xylan esterase, ... | 著者 | Mazurkewich, S, Seveso, A, Banerjee, S, Lo Leggio, L, Larsbrink, J. | 登録日 | 2023-08-14 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Polysaccharide utilization loci from Bacteroidota encode CE15 enzymes with possible roles in cleaving pectin-lignin bonds. Appl.Environ.Microbiol., 90, 2024
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3VSB
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![BU of 3vsb by Molmil](/molmil-images/mine/3vsb) | SUBTILISIN CARLSBERG D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | 分子名称: | SODIUM ION, SUBTILISIN CARLSBERG, TYPE VIII | 著者 | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | 登録日 | 1997-09-25 | 公開日 | 1998-03-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
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8DOY
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![BU of 8doy by Molmil](/molmil-images/mine/8doy) | Crystal structure of SARS-CoV-2 main protease in complex with an inhibitor TKB-198 | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3C-like proteinase nsp5, ... | 著者 | Bulut, H, Hayashi, H, Tsuji, K, Kuwata, N, Das, D, Tamamura, H, Mitsuya, H. | 登録日 | 2022-07-14 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Potent and biostable inhibitors of the main protease of SARS-CoV-2. Iscience, 25, 2022
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6GGO
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![BU of 6ggo by Molmil](/molmil-images/mine/6ggo) | Crystal structure of Salmonella zinc metalloprotease effector GtgA | 分子名称: | Bacteriophage virulence determinant, CHLORIDE ION, ZINC ION | 著者 | Jennings, E, Esposito, D, Rittinger, K, Thurston, T. | 登録日 | 2018-05-03 | 公開日 | 2018-08-29 | 最終更新日 | 2018-10-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B. J. Biol. Chem., 293, 2018
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6GGR
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![BU of 6ggr by Molmil](/molmil-images/mine/6ggr) | Crystal structure of Salmonella zinc metalloprotease effector GtgA in complex with p65 | 分子名称: | Bacteriophage virulence determinant, CHLORIDE ION, Transcription factor p65 | 著者 | Jennings, E, Esposito, D, Rittinger, K, Thurston, T. | 登録日 | 2018-05-03 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | 主引用文献 | Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B. J. Biol. Chem., 293, 2018
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5AOT
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![BU of 5aot by Molmil](/molmil-images/mine/5aot) | Very high resolution structure of a novel carbohydrate binding module from Ruminococcus flavefaciens FD-1 endoglucanase Cel5A | 分子名称: | CACODYLATE ION, Carbohydrate binding module, GLYCEROL | 著者 | Pires, A.J, Ribeiro, T, Thompson, A, Venditto, I, Fernandes, V.O, Bule, P, Santos, H, Alves, V.D, Pires, V, Ferreira, L.M.A, Fontes, C.M.G.A, Najmudin, S. | 登録日 | 2015-09-11 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.02 Å) | 主引用文献 | Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5CYV
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![BU of 5cyv by Molmil](/molmil-images/mine/5cyv) | Crystal structure of CouR from Rhodococcus jostii RHA1 bound to p-coumaroyl-CoA | 分子名称: | ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Stogios, P.J, Xu, X, Dong, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-07-30 | 公開日 | 2015-08-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism. Nucleic Acids Res., 44, 2016
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3K45
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![BU of 3k45 by Molmil](/molmil-images/mine/3k45) | Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase | 分子名称: | 5-[(1Z)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V. | 登録日 | 2009-10-05 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg.Med.Chem., 17, 2009
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3K47
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![BU of 3k47 by Molmil](/molmil-images/mine/3k47) | Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase | 分子名称: | 5-[(1E)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Cody, V, Pace, J, Queener, S.F, Gangjee, A. | 登録日 | 2009-10-05 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg.Med.Chem., 17, 2009
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1YD6
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![BU of 1yd6 by Molmil](/molmil-images/mine/1yd6) | Crystal structure of the GIY-YIG N-terminal endonuclease domain of UvrC from Bacillus caldotenax | 分子名称: | CHLORIDE ION, SULFATE ION, UvrC | 著者 | Truglio, J.J, Rhau, B, Croteau, D.L, Wang, L, Skorvaga, M, Karakas, E, DellaVecchia, M.J, Wang, H, Van Houten, B, Kisker, C. | 登録日 | 2004-12-23 | 公開日 | 2005-03-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into the first incision reaction during nucleotide excision repair Embo J., 24, 2005
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5AOS
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![BU of 5aos by Molmil](/molmil-images/mine/5aos) | Structure of a novel carbohydrate binding module from Ruminococcus flavefaciens FD-1 endoglucanase Cel5A solved at the As edge | 分子名称: | CACODYLATE ION, Carbohydrate binding module, GLYCEROL | 著者 | Pires, A.J, Ribeiro, T, Thompson, A, Venditto, I, Fernandes, V.O, Bule, P, Santos, H, Alves, V.D, Pires, V, Ferreira, L.M.A, Fontes, C.M.G.A, Najmudin, S. | 登録日 | 2015-09-11 | 公開日 | 2016-06-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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4UZN
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![BU of 4uzn by Molmil](/molmil-images/mine/4uzn) | The native structure of the family 46 carbohydrate-binding module (CBM46) of endo-beta-1,4-glucanase B (Cel5B) from Bacillus halodurans | 分子名称: | ENDO-BETA-1,4-GLUCANASE (CELULASE B) | 著者 | Venditto, I, Santos, H, Ferreira, L.M.A, Sakka, K, Fontes, C.M.G.A, Najmudin, S. | 登録日 | 2014-09-05 | 公開日 | 2015-02-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Family 46 Carbohydrate-Binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and Beta-1,3-1,4-Glucans Through Distinct Mechanisms. J.Biol.Chem., 290, 2015
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8FW7
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![BU of 8fw7 by Molmil](/molmil-images/mine/8fw7) | Histone from Bdellovibrio bacteriovorus bound to dsDNA | 分子名称: | CBFD_NFYB_HMF domain-containing protein, DNA (5'-D(P*AP*T)-3'), DNA (5'-D(P*CP*AP*T)-3') | 著者 | Laursen, S.P, Luger, K. | 登録日 | 2023-01-20 | 公開日 | 2023-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus. Nat Microbiol, 8, 2023
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8FVX
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![BU of 8fvx by Molmil](/molmil-images/mine/8fvx) | Histone from Bdellovibrio bacteriovorus | 分子名称: | CBFD_NFYB_HMF domain-containing protein | 著者 | Laursen, S.P, Luger, K. | 登録日 | 2023-01-19 | 公開日 | 2023-08-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Histones with an unconventional DNA-binding mode in vitro are major chromatin constituents in the bacterium Bdellovibrio bacteriovorus. Nat Microbiol, 8, 2023
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4UHU
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![BU of 4uhu by Molmil](/molmil-images/mine/4uhu) | W229D mutant of the last common ancestor of Gram-negative bacteria (GNCA) beta-lactamase class A | 分子名称: | ACETATE ION, FORMIC ACID, GNCA LACTAMASE W229D | 著者 | Gavira, J.A, Risso, V.A, Martinez-Rodriguez, S, Sanchez-Ruiz, J.M. | 登録日 | 2015-03-25 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.305 Å) | 主引用文献 | De novo active sites for resurrected Precambrian enzymes. Nat Commun, 8, 2017
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6IK5
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![BU of 6ik5 by Molmil](/molmil-images/mine/6ik5) | Crystal structure of tomato beta-galactosidase (TBG) 4 in complex with galactose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | 著者 | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | 登録日 | 2018-10-15 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation. Planta, 252, 2020
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6IK7
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![BU of 6ik7 by Molmil](/molmil-images/mine/6ik7) | Crystal structure of tomato beta-galactosidase (TBG) 4 in complex with beta-1,3-galactobiose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | 著者 | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | 登録日 | 2018-10-15 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation. Planta, 252, 2020
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4USO
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![BU of 4uso by Molmil](/molmil-images/mine/4uso) | X-ray structure of the CCL2 lectin in complex with sialyl lewis X | 分子名称: | CCL2 LECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Bleuler-Martinez, S, Varrot, A, Schubert, M, Stutz, M, Sieber, R, Hengartner, M, Aebi, M, Kunzler, M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes. Glycobiology, 27, 2017
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4USP
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![BU of 4usp by Molmil](/molmil-images/mine/4usp) | X-ray structure of the dimeric CCL2 lectin in native form | 分子名称: | CCL2 LECTIN, CHLORIDE ION, PHOSPHATE ION | 著者 | Bleuler-Martinez, S, Varrot, A, Schubert, M, Stutz, M, Sieber, R, Hengartner, M, Aebi, M, Kunzler, M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes. Glycobiology, 27, 2017
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6IK8
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![BU of 6ik8 by Molmil](/molmil-images/mine/6ik8) | Crystal structure of tomato beta-galactosidase (TBG) 4 in complex with beta-1,6-galactobiose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | 著者 | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | 登録日 | 2018-10-15 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation. Planta, 252, 2020
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6IK6
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![BU of 6ik6 by Molmil](/molmil-images/mine/6ik6) | Crystal structure of Tomato beta-galactosidase (TBG) 4 with beta-1,4-galactobiose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase, ... | 著者 | Matsuyama, K, Nakae, S, Igarashi, K, Tada, T, Ishimaru, M. | 登録日 | 2018-10-15 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.791 Å) | 主引用文献 | Substrate-recognition mechanism of tomato beta-galactosidase 4 using X-ray crystallography and docking simulation. Planta, 252, 2020
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5EEG
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![BU of 5eeg by Molmil](/molmil-images/mine/5eeg) | Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with tetrazole-SAH | 分子名称: | (2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-[[(3~{S})-3-azanyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)propyl]sulfanylmethyl]oxolane-3,4-diol, Carminomycin 4-O-methyltransferase DnrK | 著者 | Wang, F, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2015-10-22 | 公開日 | 2015-12-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.255 Å) | 主引用文献 | Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. Acs Chem.Biol., 11, 2016
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6YAS
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![BU of 6yas by Molmil](/molmil-images/mine/6yas) | HYDROXYNITRILE LYASE FROM HEVEA BRASILIENSIS, ROOM TEMPERATURE STRUCTURE | 分子名称: | PROTEIN (HYDROXYNITRILE LYASE), SULFATE ION | 著者 | Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C. | 登録日 | 1999-03-15 | 公開日 | 1999-10-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis. Protein Sci., 8, 1999
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6YUG
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![BU of 6yug by Molmil](/molmil-images/mine/6yug) | Crystal structure of C. parvum GNA1 in complex with acetyl-CoA and glucose 6P. | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, ACETYL COENZYME *A, Diamine acetyltransferase | 著者 | Chi, J, Cova, M, de las Rivas, M, Medina, A, Borges, R, Leivar, P, Planas, A, Uson, I, Hurtado-Guerrero, R, Izquierdo, L. | 登録日 | 2020-04-27 | 公開日 | 2020-09-30 | 最終更新日 | 2020-11-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N -Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development. Mbio, 11, 2020
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5FU3
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![BU of 5fu3 by Molmil](/molmil-images/mine/5fu3) | The complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition | 分子名称: | CBM74-RFGH5, SODIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Basle, A, Luis, A.S, Venditto, I, Gilbert, H.J. | 登録日 | 2016-01-20 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Complexity of the Ruminococcus Flavefaciens Cellulosome Reflects an Expansion in Glycan Recognition. Proc.Natl.Acad.Sci.USA, 113, 2016
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