Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6R1U
DownloadVisualize
BU of 6r1u by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2
分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ...
著者Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
登録日2019-03-15
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.36 Å)
主引用文献A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
6R25
DownloadVisualize
BU of 6r25 by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3
分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ...
著者Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
登録日2019-03-15
公開日2019-04-24
最終更新日2025-04-09
実験手法ELECTRON MICROSCOPY (4.61 Å)
主引用文献A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
3F0T
DownloadVisualize
BU of 3f0t by Molmil
Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT
分子名称: N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine, SULFATE ION, Thymidine kinase
著者Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L.
登録日2008-10-26
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
1RFG
DownloadVisualize
BU of 1rfg by Molmil
Crystal Structure of Human Purine Nucleoside Phosphorylase Complexed with Guanosine
分子名称: GUANOSINE, Purine nucleoside phosphorylase, SULFATE ION
著者Canduri, F, Silva, R.G, Dos Santos, D.M, Palma, M.S, Basso, L.A, Santos, D.S, de Azevedo, W.F.
登録日2003-11-09
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of human PNP complexed with ligands.
Acta Crystallogr.,Sect.D, 61, 2005
8RSA
DownloadVisualize
BU of 8rsa by Molmil
CRYSTAL STRUCTURE OF TWO COVALENT NUCLEOSIDE DERIVATIVES OF RIBONUCLEASE A
分子名称: 3'-DEOXY-3'-ACETAMIDO-THYMIDINE, RIBONUCLEASE A
著者Nachman, J, Wlodawer, A.
登録日1989-08-28
公開日1991-04-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of two covalent nucleoside derivatives of ribonuclease A.
Biochemistry, 29, 1990
4RW8
DownloadVisualize
BU of 4rw8 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor'
分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-12-01
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.878 Å)
主引用文献Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants.
J.Med.Chem., 58, 2015
1ZS6
DownloadVisualize
BU of 1zs6 by Molmil
structure of human nucleoside-diphosphate kinase 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3
著者Choe, J, Dimov, S, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2005-05-23
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human nucleoside-diphosphate kinase 3
To be Published
4RW4
DownloadVisualize
BU of 4rw4 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (K103N,Y181C) variant in complex with (E)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ494), a Non-nucleoside Inhibitor
分子名称: (2E)-3-(3-chloro-5-{4-chloro-2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-12-01
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.674 Å)
主引用文献Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants.
J.Med.Chem., 58, 2015
6R1T
DownloadVisualize
BU of 6r1t by Molmil
Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome
分子名称: DNA (147-MER), HISTONE H2A, Histone H2A, ...
著者Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A.
登録日2019-03-15
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27, 2019
4RW6
DownloadVisualize
BU of 4rw6 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) variant in complex with (E)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ494), a Non-nucleoside Inhibitor
分子名称: (2E)-3-(3-chloro-5-{4-chloro-2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-12-01
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants.
J.Med.Chem., 58, 2015
4RW9
DownloadVisualize
BU of 4rw9 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) variant in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor
分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-12-01
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.986 Å)
主引用文献Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants.
J.Med.Chem., 58, 2015
4RW7
DownloadVisualize
BU of 4rw7 by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) variant in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor
分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ...
著者Frey, K.M, Anderson, K.S.
登録日2014-12-01
公開日2015-04-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.014 Å)
主引用文献Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants.
J.Med.Chem., 58, 2015
9GD1
DownloadVisualize
BU of 9gd1 by Molmil
Structure of Chd1 bound to a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp.
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
著者Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
登録日2024-08-04
公開日2024-09-18
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
8I0T
DownloadVisualize
BU of 8i0t by Molmil
The cryo-EM structure of human Bact-III complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0P
DownloadVisualize
BU of 8i0p by Molmil
The cryo-EM structure of human pre-Bact complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0R
DownloadVisualize
BU of 8i0r by Molmil
The cryo-EM structure of human Bact-I complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0V
DownloadVisualize
BU of 8i0v by Molmil
The cryo-EM structure of human post-Bact complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0S
DownloadVisualize
BU of 8i0s by Molmil
The cryo-EM structure of human Bact-II complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0W
DownloadVisualize
BU of 8i0w by Molmil
The cryo-EM structure of human C complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
8I0U
DownloadVisualize
BU of 8i0u by Molmil
The cryo-EM structure of human Bact-IV complex
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ...
著者Zhan, X, Lu, Y, Shi, Y.
登録日2023-01-11
公開日2024-07-31
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for the activation of human spliceosome.
Nat Commun, 15, 2024
4R5P
DownloadVisualize
BU of 4r5p by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) with DNA and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor
分子名称: 5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', 5'-D(*TP*GP*GP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3', HIV-1 reverse transcriptase, ...
著者Das, K, Martinez, S.E, Arnold, E.
登録日2014-08-21
公開日2015-03-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.
Proc.Natl.Acad.Sci.USA, 112, 2015
1PAE
DownloadVisualize
BU of 1pae by Molmil
nucleoside diphosphate kinase
分子名称: Nucleoside diphosphate kinase, cytosolic, SELENIUM ATOM
著者Strub, M.-P, Hoh, F, Sanchez, J.-F, Strub, J.M, Bock, A, Aumelas, A, Dumas, C.
登録日2003-05-14
公開日2003-11-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Selenomethionine and Selenocysteine Double Labeling Strategy for Crystallographic Phasing
Structure, 11, 2003
8HY0
DownloadVisualize
BU of 8hy0 by Molmil
Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
9GD0
DownloadVisualize
BU of 9gd0 by Molmil
Structure of a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp.
分子名称: DNA (250-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
登録日2024-08-04
公開日2024-09-18
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024
9GD2
DownloadVisualize
BU of 9gd2 by Molmil
Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp.
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ...
著者Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L.
登録日2024-08-04
公開日2024-09-18
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT.
Mol.Cell, 84, 2024

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon