PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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6R1U	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 2 分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A, ... 著者 Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. 登録日 2019-03-15 公開日 2019-04-24 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
6R25	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 3 分子名称: DNA (147-MER), FLAVIN-ADENINE DINUCLEOTIDE, H2B, ... 著者 Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. 登録日 2019-03-15 公開日 2019-04-24 最終更新日 2025-04-09 実験手法 ELECTRON MICROSCOPY (4.61 Å) 主引用文献 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
3F0T	Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT 分子名称: N-Methyl-6-(1,3-dihydroxy-isobutyl)thymine, SULFATE ION, Thymidine kinase 著者 Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L. 登録日 2008-10-26 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo. Nucleosides Nucleotides Nucleic Acids, 30, 2011
1RFG	Crystal Structure of Human Purine Nucleoside Phosphorylase Complexed with Guanosine 分子名称: GUANOSINE, Purine nucleoside phosphorylase, SULFATE ION 著者 Canduri, F, Silva, R.G, Dos Santos, D.M, Palma, M.S, Basso, L.A, Santos, D.S, de Azevedo, W.F. 登録日 2003-11-09 公開日 2004-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of human PNP complexed with ligands. Acta Crystallogr.,Sect.D, 61, 2005
8RSA	CRYSTAL STRUCTURE OF TWO COVALENT NUCLEOSIDE DERIVATIVES OF RIBONUCLEASE A 分子名称: 3'-DEOXY-3'-ACETAMIDO-THYMIDINE, RIBONUCLEASE A 著者 Nachman, J, Wlodawer, A. 登録日 1989-08-28 公開日 1991-04-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of two covalent nucleoside derivatives of ribonuclease A. Biochemistry, 29, 1990
4RW8	Crystal Structure of HIV-1 Reverse Transcriptase in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor' 分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... 著者 Frey, K.M, Anderson, K.S. 登録日 2014-12-01 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.878 Å) 主引用文献 Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
1ZS6	structure of human nucleoside-diphosphate kinase 3 分子名称: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3 著者 Choe, J, Dimov, S, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2005-05-23 公開日 2005-06-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of human nucleoside-diphosphate kinase 3 To be Published
4RW4	Crystal Structure of HIV-1 Reverse Transcriptase (K103N,Y181C) variant in complex with (E)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ494), a Non-nucleoside Inhibitor 分子名称: (2E)-3-(3-chloro-5-{4-chloro-2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... 著者 Frey, K.M, Anderson, K.S. 登録日 2014-12-01 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.674 Å) 主引用文献 Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
6R1T	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome 分子名称: DNA (147-MER), HISTONE H2A, Histone H2A, ... 著者 Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. 登録日 2019-03-15 公開日 2019-04-24 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
4RW6	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) variant in complex with (E)-3-(3-chloro-5-(4-chloro-2-(2-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ494), a Non-nucleoside Inhibitor 分子名称: (2E)-3-(3-chloro-5-{4-chloro-2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... 著者 Frey, K.M, Anderson, K.S. 登録日 2014-12-01 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.631 Å) 主引用文献 Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
4RW9	Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) variant in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor 分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... 著者 Frey, K.M, Anderson, K.S. 登録日 2014-12-01 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.986 Å) 主引用文献 Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
4RW7	Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) variant in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor 分子名称: (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... 著者 Frey, K.M, Anderson, K.S. 登録日 2014-12-01 公開日 2015-04-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.014 Å) 主引用文献 Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
9GD1	Structure of Chd1 bound to a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp. 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... 著者 Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. 登録日 2024-08-04 公開日 2024-09-18 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
8I0T	The cryo-EM structure of human Bact-III complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0P	The cryo-EM structure of human pre-Bact complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-06-25 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0R	The cryo-EM structure of human Bact-I complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0V	The cryo-EM structure of human post-Bact complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0S	The cryo-EM structure of human Bact-II complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0W	The cryo-EM structure of human C complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
8I0U	The cryo-EM structure of human Bact-IV complex 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... 著者 Zhan, X, Lu, Y, Shi, Y. 登録日 2023-01-11 公開日 2024-07-31 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
4R5P	Crystal structure of HIV-1 reverse transcriptase (RT) with DNA and a nucleoside triphosphate mimic alpha-carboxy nucleoside phosphonate inhibitor 分子名称: 5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3', 5'-D(*TP*GP*GP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3', HIV-1 reverse transcriptase, ... 著者 Das, K, Martinez, S.E, Arnold, E. 登録日 2014-08-21 公開日 2015-03-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.894 Å) 主引用文献 Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics. Proc.Natl.Acad.Sci.USA, 112, 2015
1PAE	nucleoside diphosphate kinase 分子名称: Nucleoside diphosphate kinase, cytosolic, SELENIUM ATOM 著者 Strub, M.-P, Hoh, F, Sanchez, J.-F, Strub, J.M, Bock, A, Aumelas, A, Dumas, C. 登録日 2003-05-14 公開日 2003-11-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Selenomethionine and Selenocysteine Double Labeling Strategy for Crystallographic Phasing Structure, 11, 2003
8HY0	Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome 分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
9GD0	Structure of a hexasome-nucleosome complex with a dyad-to-dyad distance of 103 bp. 分子名称: DNA (250-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. 登録日 2024-08-04 公開日 2024-09-18 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024
9GD2	Structure of Chd1 bound to a dinucleosome with a dyad-to-dyad distance of 103 bp. 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... 著者 Engeholm, M, Roske, J.J, Oberbeckmann, E, Dienemann, C, Lidschreiber, M, Cramer, P, Farnung, L. 登録日 2024-08-04 公開日 2024-09-18 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Mol.Cell, 84, 2024

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