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8TZW
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Crystal structure of 10E8-GT4 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
分子名称: 10E8-GT4 epitope scaffold, 10E8-IGL1 Fab Light Chain, 10E8-IGL1 Fab heavy chain
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8U08
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BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
分子名称: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
8U03
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BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
分子名称: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
2M66
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BU of 2m66 by Molmil
Endoplasmic reticulum protein 29 (ERp29) C-terminal domain: 3D Protein Fold Determination from Backbone Amide Pseudocontact Shifts Generated by Lanthanide Tags at Multiple Sites
分子名称: Endoplasmic reticulum resident protein 29
著者Yagi, H, Pilla, K, Maleckis, A, Graham, B, Huber, T, Otting, G.
登録日2013-03-26
公開日2013-07-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Three-dimensional protein fold determination from backbone amide pseudocontact shifts generated by lanthanide tags at multiple sites
Structure, 21, 2013
4WAI
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BU of 4wai by Molmil
Structural characterization of the late competence protein ComFB from Bacillus subtilis.
分子名称: ComF operon protein 2, ZINC ION
著者Sysoeva, T.A, Bane, L.B, Xiao, D, Gaudet, R, Burton, B.M.
登録日2014-08-29
公開日2014-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.427 Å)
主引用文献Structural characterization of the late competence protein ComFB from Bacillus subtilis.
Biosci.Rep., 35, 2015
6WDD
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BU of 6wdd by Molmil
Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure V-A)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WDM
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BU of 6wdm by Molmil
Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-B2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
4U3P
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BU of 4u3p by Molmil
Octameric RNA duplex co-crystallized with strontium(II)chloride
分子名称: RNA (5'-R(*UP*CP*GP*UP*AP*CP*GP*A)-3'), STRONTIUM ION
著者Schaffer, M.F, Spingler, B, Schnabl, J, Peng, G, Olieric, V, Sigel, R.K.O.
登録日2014-07-22
公開日2015-07-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.866 Å)
主引用文献The X-ray Structures of Six Octameric RNA Duplexes in the Presence of Different Di- and Trivalent Cations.
Int J Mol Sci, 17, 2016
2YOP
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BU of 2yop by Molmil
Long wavelength S-SAD structure of FAM3B PANDER
分子名称: GLYCEROL, PROTEIN FAM3B
著者Johansson, P, Bernstrom, J, Gorman, T, Oster, L, Backstrom, S, Schweikart, F, Xu, B, Xue, Y, Holmberg Schiavone, L.
登録日2012-10-26
公開日2013-01-30
最終更新日2013-02-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fam3B Pander and Fam3C Ilei Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-Like Fold.
Structure, 21, 2013
2YS0
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BU of 2ys0 by Molmil
Solution structure of the Somatomedin B domain of human Ectonucleotide pyrophosphatase/phosphodiesterase family member
分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
著者Abe, H, Sasagawa, A, Tochio, N, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-03
公開日2007-10-09
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the Somatomedin B domain of human Ectonucleotide pyrophosphatase/phosphodiesterase family member
To be Published
4TYM
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BU of 4tym by Molmil
Crystal structure of purine nucleoside phosphorylase from Streptococcus agalactiae 2603V/R, NYSGRC Target 030935
分子名称: Purine nucleoside phosphorylase DeoD-type, SULFATE ION
著者Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-07-08
公開日2014-07-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Crystal structure of purine nucleoside phosphorylase from Streptococcus agalactiae 2603V/R, NYSGRC Target 030935.
To Be Published
5VLN
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BU of 5vln by Molmil
NMR structure of the N-domain of troponin C bound to switch region of troponin I
分子名称: Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle
著者Cai, F, Hwang, P.M, Sykes, B.D.
登録日2017-04-25
公開日2017-05-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
2B60
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BU of 2b60 by Molmil
Structure of HIV-1 protease mutant bound to Ritonavir
分子名称: GLYCEROL, Gag-Pol polyprotein, RITONAVIR
著者Clemente, J.C, Stow, L.R, Janka, L.K, Jeung, J.A, Desai, K.A, Govindasamy, L, Agbandje-McKenna, M, McKenna, R, Goodenow, M.M, Dunn, B.M.
登録日2005-09-29
公開日2006-11-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献In vivo, kinetic, and structural analysis of the development of ritonavir resistance
To be Published
6D7A
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BU of 6d7a by Molmil
Structure of T. gondii PLP1 beta-rich domain
分子名称: Perforin-like protein 1, SODIUM ION
著者Guerra, A.J, Koropatkin, N.M, Wawrzak, Z, Bahr, C.M.E, Carruthers, V.B.
登録日2018-04-24
公開日2018-05-16
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress.
PLoS Pathog., 14, 2018
2YBA
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BU of 2yba by Molmil
Crystal structure of Nurf55 in complex with histone H3
分子名称: HISTONE H3, PROBABLE HISTONE-BINDING PROTEIN CAF1
著者Schmitges, F.W, Prusty, A.B, Faty, M, Stutzer, A, Lingaraju, G.M, Aiwazian, J, Sack, R, Hess, D, Li, L, Zhou, S, Bunker, R.D, Wirth, U, Bouwmeester, T, Bauer, A, Ly-Hartig, N, Zhao, K, Chan, H, Gu, J, Gut, H, Fischle, W, Muller, J, Thoma, N.H.
登録日2011-03-02
公開日2011-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Histone Methylation by Prc2 is Inhibited by Active Chromatin Marks
Mol.Cell, 42, 2011
2AMO
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BU of 2amo by Molmil
Loose Dimer of a Bacillus subtilis Nitric Oxide Synthase
分子名称: Nitric oxide synthase oxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Pant, K, Crane, B.R.
登録日2005-08-09
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a loose dimer: an intermediate in nitric oxide synthase assembly.
J.Mol.Biol., 352, 2005
4TUH
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BU of 4tuh by Molmil
Bcl-xL in complex with inhibitor (Compound 10)
分子名称: 1,2-ETHANEDIOL, 2-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-5-{3-[4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy]propyl}-1,3-thiazole-4-carboxylic acid, ACETATE ION, ...
著者Czabotar, P.E, Lessense, G, Smith, B.J, Colman, P.M.
登録日2014-06-24
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.
Acs Med.Chem.Lett., 5, 2014
6WDJ
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BU of 6wdj by Molmil
Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-A1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WNV
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BU of 6wnv by Molmil
70S ribosome without free 5S rRNA and with a perturbed PTC
分子名称: 16S ribosomal RNA, 23s-5s joint ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N.
登録日2020-04-23
公開日2020-06-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly.
Nat Commun, 11, 2020
8SKU
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BU of 8sku by Molmil
Structure of human SIgA1 in complex with human CD89 (FcaR1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
著者Liu, Q, Stadtmueller, B.M.
登録日2023-04-20
公開日2023-10-25
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
6D4W
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BU of 6d4w by Molmil
M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 35 (VCC620637)
分子名称: 2-(4-fluorophenyl)-1-{4-[(isoquinolin-5-yl)sulfonyl]piperazin-1-yl}ethan-1-one, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
著者Ascher, D.B, Pacitto, A, Blundell, T.L.
登録日2018-04-18
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.
Eur.J.Med.Chem., 174, 2019
5KLY
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BU of 5kly by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant adenosine nucleoside phosphoramidate substrate complex
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Histidine triad nucleotide-binding protein 1, ...
著者Maize, K.M, Finzel, B.C.
登録日2016-06-26
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14, 2017
2YZ2
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BU of 2yz2 by Molmil
Crystal structure of the ABC transporter in the cobalt transport system
分子名称: Putative ABC transporter ATP-binding protein TM_0222
著者Ethayathullah, A.S, Bessho, Y, Padmanabhan, B, Singh, T.P, Kaur, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-02
公開日2007-11-06
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ABC transporter in the cobalt transport system
To be Published
5KM2
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BU of 5km2 by Molmil
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) CMP catalytic product complex
分子名称: CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, ...
著者Maize, K.M, Finzel, B.C.
登録日2016-06-26
公開日2017-06-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
Mol. Pharm., 14, 2017
2AIO
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BU of 2aio by Molmil
Metallo beta lactamase L1 from Stenotrophomonas maltophilia complexed with hydrolyzed moxalactam
分子名称: (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO XYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ...
著者Spencer, J, Read, J, Sessions, R.B, Howell, S, Blackburn, G.M, Gamblin, S.J.
登録日2005-07-30
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Antibiotic Recognition by Binuclear Metallo-beta-Lactamases Revealed by X-ray Crystallography
J.Am.Chem.Soc., 127, 2005

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件を2024-08-14に公開中

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