1CW4
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8AN8
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![BU of 8an8 by Molmil](/molmil-images/mine/8an8) | Crystal structure of wild-type c-MET bound by compound 7. | 分子名称: | 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, Hepatocyte growth factor receptor, SULFATE ION | 著者 | Collie, G.W. | 登録日 | 2022-08-04 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Discovery of a selective c-MET inhibitor with a novel binding mode. Bioorg.Med.Chem.Lett., 75, 2022
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1CZP
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![BU of 1czp by Molmil](/molmil-images/mine/1czp) | ANABAENA PCC7119 [2FE-2S] FERREDOXIN IN THE REDUCED AND OXIXIZED STATE AT 1.17 A | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I | 著者 | Morales, R, Charon, M.H, Frey, M. | 登録日 | 1999-09-06 | 公開日 | 2000-01-14 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Refined X-ray structures of the oxidized, at 1.3 A, and reduced, at 1.17 A, [2Fe-2S] ferredoxin from the cyanobacterium Anabaena PCC7119 show redox-linked conformational changes. Biochemistry, 38, 1999
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8ANS
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![BU of 8ans by Molmil](/molmil-images/mine/8ans) | Crystal structure of D1228V c-MET bound by compound 1. | 分子名称: | 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, GLYCEROL, Hepatocyte growth factor receptor | 著者 | Collie, G.W. | 登録日 | 2022-08-05 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Discovery of a selective c-MET inhibitor with a novel binding mode. Bioorg.Med.Chem.Lett., 75, 2022
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5TPY
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![BU of 5tpy by Molmil](/molmil-images/mine/5tpy) | Crystal structure of an exonuclease resistant RNA from Zika virus | 分子名称: | HEXANE-1,6-DIOL, MAGNESIUM ION, RNA (71-MER) | 著者 | Akiyama, B.M, Laurence, H.M, Massey, A.R, Costantino, D.A, Xie, X, Yang, Y, Shi, P.-Y, Nix, J.C, Beckham, J.D, Kieft, J.S. | 登録日 | 2016-10-21 | 公開日 | 2016-12-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | 主引用文献 | Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science, 354, 2016
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1CW7
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4FQF
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4FR8
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7ZS5
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![BU of 7zs5 by Molmil](/molmil-images/mine/7zs5) | Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-06 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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7ZPQ
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![BU of 7zpq by Molmil](/molmil-images/mine/7zpq) | Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-04-28 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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7ZRS
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![BU of 7zrs by Molmil](/molmil-images/mine/7zrs) | Structure of the RQT-bound 80S ribosome from S. cerevisiae (C2) - composite map | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-05 | 公開日 | 2023-02-22 | 最終更新日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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7ZUX
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![BU of 7zux by Molmil](/molmil-images/mine/7zux) | Collided ribosome in a disome unit from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-13 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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7ZUW
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![BU of 7zuw by Molmil](/molmil-images/mine/7zuw) | Structure of RQT (C1) bound to the stalled ribosome in a disome unit from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R. | 登録日 | 2022-05-13 | 公開日 | 2023-02-22 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis for clearing of ribosome collisions by the RQT complex. Nat Commun, 14, 2023
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7ZES
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![BU of 7zes by Molmil](/molmil-images/mine/7zes) | Human SLFN11 dimer bound to ssDNA | 分子名称: | DNA (5'-D(P*CP*GP*CP*GP*T)-3'), MAGNESIUM ION, Schlafen family member 11, ... | 著者 | Metzner, F.J, Kugler, M, Wenzl, S.J, Lammens, K. | 登録日 | 2022-03-31 | 公開日 | 2022-09-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanistic understanding of human SLFN11. Nat Commun, 13, 2022
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7ZEL
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![BU of 7zel by Molmil](/molmil-images/mine/7zel) | Human SLFN11 dimer apoenzyme | 分子名称: | MAGNESIUM ION, Schlafen family member 11, ZINC ION | 著者 | Metzner, F.J, Kugler, M, Wenzl, S.J, Lammens, K. | 登録日 | 2022-03-31 | 公開日 | 2022-09-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanistic understanding of human SLFN11. Nat Commun, 13, 2022
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7ZEP
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![BU of 7zep by Molmil](/molmil-images/mine/7zep) | Human SLFN11 E209A dimer | 分子名称: | Schlafen family member 11, ZINC ION | 著者 | Metzner, F.J, Kugler, M, Wenzl, S.J, Lammens, K. | 登録日 | 2022-03-31 | 公開日 | 2022-09-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanistic understanding of human SLFN11. Nat Commun, 13, 2022
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2VA3
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![BU of 2va3 by Molmil](/molmil-images/mine/2va3) | Complex structure of Sulfolobus solfataricus DPO4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *CP*TP*A)-3', 5'-D(*TP*TP*CP*AP*DFTP*TP*AP*GP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Irimia, A, Pallan, P.S, Egli, M. | 登録日 | 2007-08-28 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Structure and Activity of Y-Class DNA Polymerase Dpo4 from Sulfolobus Solfataricus with Templates Containing the Hydrophobic Thymine Analog 2,4-Difluorotoluene. J.Biol.Chem., 282, 2007
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7YZZ
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![BU of 7yzz by Molmil](/molmil-images/mine/7yzz) | Crystal structure of Vibrio alkaline phosphatase in 0.5 M NaCl | 分子名称: | 1,2-ETHANEDIOL, Alkaline phosphatase, CHLORIDE ION, ... | 著者 | Markusson, S, Hjorleifsson, J.G, Kursula, P, Asgeirsson, B. | 登録日 | 2022-02-21 | 公開日 | 2022-11-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Structural Characterization of Functionally Important Chloride Binding Sites in the Marine Vibrio Alkaline Phosphatase. Biochemistry, 61, 2022
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3RZ0
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![BU of 3rz0 by Molmil](/molmil-images/mine/3rz0) | Fluoroalkyl and Alkyl Chains Have Similar Hydrophobicities in Binding to the Hydrophobic Wall of Carbonic Anhydrase | 分子名称: | Carbonic anhydrase 2, N-butyl-4-sulfamoylbenzamide, ZINC ION | 著者 | Snyder, P.W, Bai, S, Heroux, A, Whitesides, G.W. | 登録日 | 2011-05-11 | 公開日 | 2011-08-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Fluoroalkyl and alkyl chains have similar hydrophobicities in binding to the "hydrophobic wall" of carbonic anhydrase. J.Am.Chem.Soc., 133, 2011
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5UZT
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8AGU
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![BU of 8agu by Molmil](/molmil-images/mine/8agu) | Yeast RQC complex in state E | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AAF
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![BU of 8aaf by Molmil](/molmil-images/mine/8aaf) | Yeast RQC complex in state G | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-01 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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1CK6
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![BU of 1ck6 by Molmil](/molmil-images/mine/1ck6) | BINDING MODE OF SALICYLHYDROXAMIC ACID TO ARTHROMYCES RAMOSUS PEROXIDASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN (PEROXIDASE), ... | 著者 | Fukuyama, K, Itakura, H. | 登録日 | 1999-04-28 | 公開日 | 1999-12-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Binding of salicylhydroxamic acid and several aromatic donor molecules to Arthromyces ramosus peroxidase, investigated by X-ray crystallography, optical difference spectroscopy, NMR relaxation, molecular dynamics, and kinetics. Biochemistry, 38, 1999
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2X0W
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![BU of 2x0w by Molmil](/molmil-images/mine/2x0w) | STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-dimethoxy- 2-methylbenzothiazole | 分子名称: | 5,6-DIMETHOXY-2-METHYL-1,3-BENZOTHIAZOLE, CELLULAR TUMOR ANTIGEN P53, ZINC ION | 著者 | Kaar, J.L, Basse, N, Joerger, A.C, Fersht, A.R. | 登録日 | 2009-12-17 | 公開日 | 2010-01-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Toward the Rational Design of P53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant. Chem.Biol., 17, 2010
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1CW1
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