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2W5A
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BU of 2w5a by Molmil
Human Nek2 kinase ADP-bound
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Westwood, I, Bayliss, R.
登録日2008-12-08
公開日2008-12-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase.
J.Mol.Biol., 386, 2009
6CN9
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BU of 6cn9 by Molmil
Crystal structure of the Kinase domain of WNK1
分子名称: GLYCEROL, SULFATE ION, Serine/threonine-protein kinase WNK1
著者Akella, R, Goldsmith, E.J.
登録日2018-03-07
公開日2019-03-27
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension.
Structure, 12, 2004
8YOP
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BU of 8yop by Molmil
Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Li, X, Wang, M, Denk, T, Cheng, J.
登録日2024-03-13
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
6CT2
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BU of 6ct2 by Molmil
MYST histone acetyltransferase KAT6A/B in complex with WM-1119
分子名称: 3-fluoro-N'-[(2-fluorophenyl)sulfonyl]-5-(pyridin-2-yl)benzohydrazide, Histone acetyltransferase KAT8, MAGNESIUM ION, ...
著者Ren, B, Peat, T.S.
登録日2018-03-22
公開日2018-08-01
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (2.128 Å)
主引用文献Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature, 560, 2018
8YOO
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BU of 8yoo by Molmil
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Li, X, Wang, M, Denk, T, Cheng, J.
登録日2024-03-13
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
6D0M
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BU of 6d0m by Molmil
Polymerase Eta post-insertion binary complex with cytarabine (AraC)
分子名称: DNA (5'-D(*CP*AP*TP*GP*AP*CP*AP*GP*TP*GP*CP*T)-3'), DNA polymerase eta, DNA/RNA (5'-D(*AP*GP*CP*AP*CP*TP*GP*T)-R(P*(CAR))-3'), ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2018-04-10
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.832 Å)
主引用文献Structural basis for polymerase eta-promoted resistance to the anticancer nucleoside analog cytarabine.
Sci Rep, 8, 2018
2IS2
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BU of 2is2 by Molmil
Crystal structure of UvrD-DNA binary complex
分子名称: 33-MER, DNA helicase II, FORMIC ACID, ...
著者Yang, W, Lee, J.Y.
登録日2006-10-16
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
2ISJ
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BU of 2isj by Molmil
BluB bound to oxidized FMN
分子名称: BluB, FLAVIN MONONUCLEOTIDE
著者Larsen, N.A, Taga, M.E, Howard-Jones, A.R, Walsh, C.T, Walker, G.C.
登録日2006-10-17
公開日2007-03-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献BluB cannibalizes flavin to form the lower ligand of vitamin B12.
Nature, 446, 2007
8C60
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BU of 8c60 by Molmil
Cryo-EM structure of the human SIN3B full-length complex at 3.4 Angstrom resolution
分子名称: CALCIUM ION, Histone deacetylase 2, Isoform 2 of Paired amphipathic helix protein Sin3b, ...
著者Alfieri, C, Wan, S.M, Muhammad, R.
登録日2023-01-10
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex.
Nat Commun, 14, 2023
2W2I
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BU of 2w2i by Molmil
Crystal structure of the human 2-oxoglutarate oxygenase LOC390245
分子名称: 2-OXOGLUTARATE OXYGENASE, GLYCEROL, NICKEL (II) ION, ...
著者Yue, W.W, Ng, S, Shafqat, N, Ugochukwu, E, McDonough, M, Pike, A.C.W, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C, Oppermann, U.
登録日2008-10-31
公開日2009-01-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human Kdm4 Histone Demethylase Family.
J.Biol.Chem., 286, 2011
6D24
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BU of 6d24 by Molmil
Trypanosoma cruzi Glucose-6-P Dehydrogenase in complex with G6P
分子名称: 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A.
登録日2018-04-12
公開日2018-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
6D3I
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BU of 6d3i by Molmil
ftv7 dioxygenase with 2,4-D bound
分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, 2-OXOGLUTARIC ACID, COBALT (II) ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.196 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D3M
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BU of 6d3m by Molmil
FT_T dioxygenase with bound quizalofop
分子名称: (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
2IF7
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BU of 2if7 by Molmil
Crystal Structure of NTB-A
分子名称: CALCIUM ION, CHLORIDE ION, SLAM family member 6
著者Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C.
登録日2006-09-20
公開日2006-10-17
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
6CT6
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BU of 6ct6 by Molmil
Crystal structure of lactate dehydrogenase from Eimeria maxima with NADH and oxamate
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Lactate dehydrogenase, OXAMIC ACID, ...
著者Wirth, J.D, Xu, C, Theobald, D.L.
登録日2018-03-22
公開日2019-03-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献The Mechanistic, Structural, and Evolutionary Origin of Lactate Dehydrogenase Substrate Specificity in Apicomplexa
To Be Published
2IS6
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BU of 2is6 by Molmil
Crystal structure of UvrD-DNA-ADPMgF3 ternary complex
分子名称: 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*GP*TP*TP*AP*T)-3', ADENOSINE-5'-DIPHOSPHATE, DNA helicase II, ...
著者Yang, W, Lee, J.Y.
登録日2006-10-16
公開日2007-01-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
6D3H
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BU of 6d3h by Molmil
FT_T dioxygenase with bound dichlorprop
分子名称: (2R)-2-(2,4-dichlorophenoxy)propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
2YCC
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BU of 2ycc by Molmil
OXIDATION STATE-DEPENDENT CONFORMATIONAL CHANGES IN CYTOCHROME C
分子名称: CYTOCHROME C, HEME C, SULFATE ION
著者Berghuis, A.M, Brayer, G.D.
登録日1991-01-29
公開日1992-07-15
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Oxidation state-dependent conformational changes in cytochrome c.
J.Mol.Biol., 223, 1992
6D0O
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BU of 6d0o by Molmil
rdpA dioxygenase holoenzyme
分子名称: (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, COBALT (II) ION
著者Rydel, T.J, Sturman, E.J, Zheng, M, Evdokimov, A.
登録日2018-04-10
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D23
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BU of 6d23 by Molmil
GLUCOSE-6-P DEHYDROGENASE (APO FORM) FROM TRYPANOSOMA CRUZI
分子名称: CHLORIDE ION, GLYCEROL, Glucose-6-phosphate 1-dehydrogenase, ...
著者Botti, H, Ortiz, C, Comini, M.A, Larrieux, N, Buschiazzo, A.
登録日2018-04-12
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation.
J.Mol.Biol., 431, 2019
2J7A
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BU of 2j7a by Molmil
Crystal structure of cytochrome c nitrite reductase NrfHA complex from Desulfovibrio vulgaris
分子名称: ACETATE ION, CALCIUM ION, CYTOCHROME C NITRITE REDUCTASE NRFA, ...
著者Rodrigues, M.L, Oliveira, T.F, Pereira, I.A.C, Archer, M.
登録日2006-10-06
公開日2006-12-06
最終更新日2019-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献X-Ray Structure of the Membrane-Bound Cytochrome C Quinol Dehydrogenase Nrfh Reveals Novel Haem Coordination.
Embo J., 25, 2006
8IPT
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BU of 8ipt by Molmil
Cryo-EM structure of heme transporter CydDC from Escherichia coli in the occluded ATP bound state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPS
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BU of 8ips by Molmil
Cryo-EM structure of heme transporter CydDC from Escherichia coli in the inward facing heme loading state
分子名称: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPR
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BU of 8ipr by Molmil
Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the outward facing ATP bound state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, MAGNESIUM ION, ...
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023
8IPQ
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BU of 8ipq by Molmil
Cryo-EM structure of heme transporter CydDC from Mycobacterium smegmatis in the inward facing apo state
分子名称: Component linked with the assembly of cytochrome' ABC transporter ATP-binding protein CydC, Transmembrane ATP-binding protein ABC transporter cydD
著者Zhu, C, Li, J.
登録日2023-03-14
公開日2023-06-14
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of a prokaryotic heme transporter CydDC.
Protein Cell, 14, 2023

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