PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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3N1W	Human FPPS COMPLEX WITH FBS_02 分子名称: (5-chloro-1-benzothiophen-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-17 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3MZV	Crystal structure of a decaprenyl diphosphate synthase from Rhodobacter capsulatus 分子名称: Decaprenyl diphosphate synthase 著者 Quartararo, C.E, Patskovsky, Y, Bonanno, J.B, Rutter, M, Bain, K.T, Chang, S, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-05-13 公開日 2010-06-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
3MT9	Glycogen phosphorylase complexed with 4-nitrobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-nitrophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3MS2	Glycogen phosphorylase complexed with 4-methylbenzaldehyde-4-(beta-D-glucopyranosyl) thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(4-methylphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-29 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3M9U	Crystal structure of geranylgeranyl pyrophosphate synthase from lactobacillus brevis atcc 367 分子名称: Farnesyl-diphosphate synthase, GLYCEROL 著者 Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-03-22 公開日 2010-04-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Lactobacillus Brevis Atcc 367 To be Published
3MAV	Crystal structure of Plasmodium vivax putative farnesyl pyrophosphate synthase (Pv092040) 分子名称: Farnesyl pyrophosphate synthase, SULFATE ION 著者 Dong, A, Dunford, J, Lew, J, Wernimont, A.K, Ren, H, Zhao, Y, Koeieradzki, I, Opperman, U, Sundstrom, M, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) 登録日 2010-03-24 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J.Biol.Chem., 286, 2011
3MTB	Glycogen phosphorylase complexed with 3-chlorobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(3-chlorophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3N45	Human FPPS complex with FBS_04 and zoledronic acid/MG2+ 分子名称: (2S)-1-[(benzyloxy)carbonyl]-2,3-dihydro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, ... 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N5H	Human fpps complex with NOV_304 分子名称: 3-(carboxymethyl)-4,7-dichloro-1H-indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-25 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N6K	Human FPPS complex with NOV_823 分子名称: 1-(carboxymethyl)-1H-benzo[g]indole-2-carboxylic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-26 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3MTA	Glycogen phosphorylase complexed with 3-bromobenzaldehyde-4-(beta-D-glucopyranosyl)-thiosemicarbazone 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(3-bromophenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-04-30 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3N1V	Human FPPS COMPLEX WITH FBS_01 分子名称: (5-chloro-3-methyl-1-benzothiophen-2-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-17 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3NC4	The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors 分子名称: Glycogen phosphorylase, muscle form, N-({(2E)-2-[(2-hydroxyphenyl)methylidene]hydrazino}carbonothioyl)-beta-D-glucopyranosylamine 著者 Alexacou, K.-M. 登録日 2010-06-04 公開日 2011-01-05 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 The binding of beta-D-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: a new class of inhibitors Bioorg.Med.Chem., 18, 2010
3N3L	Human FPPS complex with FBS_03 分子名称: (6-methoxy-1-benzofuran-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-20 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N3D	Crystal structure of geranylgeranyl pyrophosphate synthase from lactobacillus brevis atcc 367 分子名称: Geranylgeranyl pyrophosphate synthase, SULFATE ION 著者 Patskovsky, Y, Toro, R, Rutter, M, Chang, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-05-19 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of Geranylgeranyl Pyrophosphate Synthase from Lactobacillus Brevis To be Published
3N49	Human FPPS COMPLEX WITH NOV_292 分子名称: FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION, naphtho[2,1-b]thiophen-1-ylacetic acid 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
7Z4T	AAL160 FAB IN COMPLEX WITH HUMAN INTERLEUKIN-1 BETA 分子名称: AAL160 Fab heavy-chain, AAL160 light-chain, Interleukin-1 beta 著者 Rondeau, J.M, Lehmann, S. 登録日 2022-03-04 公開日 2023-02-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 "Redirecting an anti-IL-1 beta antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A". Commun Biol, 6, 2023
3NBU	Crystal structure of pGI glucosephosphate isomerase 分子名称: CHLORIDE ION, Glucose-6-phosphate isomerase 著者 Alber, T, Zubieta, C, Totir, M, May, A, Echols, N. 登録日 2010-06-04 公開日 2011-06-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Macro-to-Micro Structural Proteomics: Native Source Proteins for High-Throughput Crystallization. Plos One, 7, 2012
3NJ5	Crystal structure of chicken IL-1 hydrophobic cavity mutant 157 分子名称: IL-1 beta 著者 Yin, H.S, Chen, Y.W. 登録日 2010-06-17 公開日 2011-06-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structural and functional comparison of cytokine interleukin-1 beta from chicken and human Mol.Immunol., 48, 2011
8EMS	Cryo-EM structure of human liver glycogen phosphorylase 分子名称: Glycogen phosphorylase, liver form, PYRIDOXAL-5'-PHOSPHATE 著者 Su, C, Lyu, M, Zhang, Z, Yu, E.W. 登録日 2022-09-28 公開日 2023-05-10 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
8F8K	The structure of Rv2173 from M. tuberculosis with IPP bound 分子名称: (2E,6E)-farnesyl diphosphate synthase, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, ... 著者 Johnston, J.M, Allison, T.M, Titterington, J, Beasley, C.P.H. 登録日 2022-11-22 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms. To be Published
8F8F	The structure of Rv2173 from M. tuberculosis (APO form) 分子名称: (2E,6E)-farnesyl diphosphate synthase, GLYCEROL, MAGNESIUM ION 著者 Johnston, J.M, Allison, T.M, Titterington, J. 登録日 2022-11-22 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms. To be Published
8F8L	The structure of Rv2173 from M. tuberculosis with DMAP bound 分子名称: (2E,6E)-farnesyl diphosphate synthase, CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, ... 著者 Johnston, J.M, Allison, T.M, Titterington, J. 登録日 2022-11-22 公開日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of Rv2173 from M. tuberculosis in APO-, IPP-, and DMAP-bound forms. To be Published
5QPG	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000291a 分子名称: 3-(azepan-1-ylmethyl)-1~{H}-indole, ACETATE ION, Farnesyl diphosphate synthase, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published
5QPV	PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000416a 分子名称: (2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Petrick, J.K, Nelson, E.R, Muenzker, L, Krojer, T, Douangamath, A, Brandao-Neto, J, von Delft, F, Dekker, C, Jahnke, W. 登録日 2019-03-12 公開日 2020-04-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 PanDDA analysis group deposition - FPPS screened against the DSI Fragment Library To Be Published

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